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1 1 %%% contexte clinique%%%
2 2 @article{dewan2018estimating,
3   - title={Estimating the global incidence of traumatic brain injury},
4   - author={Dewan, Michael C and Rattani, Abbas and Gupta, Saksham and Baticulon, Ronnie E and Hung, Ya-Ching and Punchak, Maria and Agrawal, Amit and Adeleye, Amos O and Shrime, Mark G and Rubiano, Andr{\'e}s M and others},
5   - journal={Journal of neurosurgery},
6   - volume={130},
7   - number={4},
8   - pages={1080--1097},
9   - year={2018},
10   - publisher={American Association of Neurological Surgeons}
  3 + title = {Estimating the global incidence of traumatic brain injury},
  4 + author = {Dewan, Michael C and Rattani, Abbas and Gupta, Saksham and Baticulon, Ronnie E and Hung, Ya-Ching and Punchak, Maria and Agrawal, Amit and Adeleye, Amos O and Shrime, Mark G and Rubiano, Andr{\'e}s M and others},
  5 + year = 2018,
  6 + journal = {Journal of neurosurgery},
  7 + publisher = {American Association of Neurological Surgeons},
  8 + volume = 130,
  9 + number = 4,
  10 + pages = {1080--1097}
11 11 }
12   -
13 12 @article{ahmed2024epidemiology,
14   - title={Epidemiology, pathophysiology, and treatment strategies of concussions: a comprehensive review},
15   - author={Ahmed, Zubair and Chaudhary, Fihr and Fraix, Marcel P and Agrawal, Devendra K},
16   - journal={Fortune journal of health sciences},
17   - volume={7},
18   - number={2},
19   - pages={197},
20   - year={2024},
21   - publisher={NIH Public Access}
  13 + title = {Epidemiology, pathophysiology, and treatment strategies of concussions: a comprehensive review},
  14 + author = {Ahmed, Zubair and Chaudhary, Fihr and Fraix, Marcel P and Agrawal, Devendra K},
  15 + year = 2024,
  16 + journal = {Fortune journal of health sciences},
  17 + publisher = {NIH Public Access},
  18 + volume = 7,
  19 + number = 2,
  20 + pages = 197
22 21 }
23   -
24 22 @article{silverberg2020management,
25   - title={Management of concussion and mild traumatic brain injury: a synthesis of practice guidelines},
26   - author={Silverberg, Noah D and Iaccarino, Mary Alexis and Panenka, William J and Iverson, Grant L and McCulloch, Karen L and Dams-O’Connor, Kristen and Reed, Nick and McCrea, Michael and Cogan, Alison M and Graf, Min Jeong Park and others},
27   - journal={Archives of Physical Medicine and Rehabilitation},
28   - volume={101},
29   - number={2},
30   - pages={382--393},
31   - year={2020},
32   - publisher={Elsevier}
  23 + title = {Management of concussion and mild traumatic brain injury: a synthesis of practice guidelines},
  24 + author = {Silverberg, Noah D and Iaccarino, Mary Alexis and Panenka, William J and Iverson, Grant L and McCulloch, Karen L and Dams-O’Connor, Kristen and Reed, Nick and McCrea, Michael and Cogan, Alison M and Graf, Min Jeong Park and others},
  25 + year = 2020,
  26 + journal = {Archives of Physical Medicine and Rehabilitation},
  27 + publisher = {Elsevier},
  28 + volume = 101,
  29 + number = 2,
  30 + pages = {382--393}
33 31 }
34   -
35 32 @article{karthigeyan2021head,
36   - title={Head injury care in a low-and middle-income country tertiary trauma center: epidemiology, systemic lacunae, and possible leads},
37   - author={Karthigeyan, Madhivanan and Gupta, Sunil Kumar and Salunke, Pravin and Dhandapani, Sivashanmugam and Wankhede, Lomesh Shankarrao and Kumar, Anurodh and Singh, Apinderpreet and Sahoo, Sushanta Kumar and Tripathi, Manjul and Gendle, Chandrashekhar and others},
38   - journal={Acta neurochirurgica},
39   - volume={163},
40   - number={10},
41   - pages={2919--2930},
42   - year={2021},
43   - publisher={Springer}
  33 + title = {Head injury care in a low-and middle-income country tertiary trauma center: epidemiology, systemic lacunae, and possible leads},
  34 + author = {Karthigeyan, Madhivanan and Gupta, Sunil Kumar and Salunke, Pravin and Dhandapani, Sivashanmugam and Wankhede, Lomesh Shankarrao and Kumar, Anurodh and Singh, Apinderpreet and Sahoo, Sushanta Kumar and Tripathi, Manjul and Gendle, Chandrashekhar and others},
  35 + year = 2021,
  36 + journal = {Acta neurochirurgica},
  37 + publisher = {Springer},
  38 + volume = 163,
  39 + number = 10,
  40 + pages = {2919--2930}
44 41 }
45   -
46   -
47 42 %%% HSA%%%
48   -
49   -
50 43 @article{d205aneurysmal,
51   - title={Aneurysmal subarachnoid hemorrhage},
52   - author={D’Souza, Stanlies},
53   - journal={Journal of neurosurgical anesthesiology},
54   - volume={27},
55   - number={3},
56   - pages={222--240},
57   - year={2015},
58   - publisher={LWW}
  44 + title = {Aneurysmal subarachnoid hemorrhage},
  45 + author = {D’Souza, Stanlies},
  46 + year = 2015,
  47 + journal = {Journal of neurosurgical anesthesiology},
  48 + publisher = {LWW},
  49 + volume = 27,
  50 + number = 3,
  51 + pages = {222--240}
59 52 }
60   -
61   -
62 53 @article{cucciolini2023intracranial,
63   - title={Intracranial pressure for clinicians: It is not just a number},
64   - author={Cucciolini, Giada and Motroni, Virginia and Czosnyka, Marek},
65   - journal={Journal of Anesthesia, Analgesia and Critical Care},
66   - volume={3},
67   - number={1},
68   - pages={31},
69   - year={2023},
70   - publisher={Springer}
  54 + title = {Intracranial pressure for clinicians: It is not just a number},
  55 + author = {Cucciolini, Giada and Motroni, Virginia and Czosnyka, Marek},
  56 + year = 2023,
  57 + journal = {Journal of Anesthesia, Analgesia and Critical Care},
  58 + publisher = {Springer},
  59 + volume = 3,
  60 + number = 1,
  61 + pages = 31
71 62 }
72   -
73 63 @inproceedings{feng2011artifact,
74   - title={Artifact removal for intracranial pressure monitoring signals: a robust solution with signal decomposition},
75   - author={Feng, Mengling and Loy, Liang Yu and Zhang, Feng and Guan, Cuntai},
76   - booktitle={2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
77   - pages={797--801},
78   - year={2011},
79   - organization={IEEE}
  64 + title = {Artifact removal for intracranial pressure monitoring signals: a robust solution with signal decomposition},
  65 + author = {Feng, Mengling and Loy, Liang Yu and Zhang, Feng and Guan, Cuntai},
  66 + year = 2011,
  67 + booktitle = {2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
  68 + pages = {797--801},
  69 + organization = {IEEE}
80 70 }
81   -
82 71 @article{megjhani2023automatic,
83   - title={Automatic identification of intracranial pressure waveform during external ventricular drainage clamping: Segmentation via wavelet analysis},
84   - author={Megjhani, Murad and Terilli, Kalijah and Kwon, Soon Bin and Nametz, Daniel and Weinerman, Bennett and Velazquez, Angela and Ghoshal, Shivani and Roh, David and Agarwal, Sachin and Connolly, E Sander and others},
85   - journal={Physiological measurement},
86   - volume={44},
87   - number={6},
88   - pages={064002},
89   - year={2023},
90   - publisher={IOP Publishing}
  72 + title = {Automatic identification of intracranial pressure waveform during external ventricular drainage clamping: Segmentation via wavelet analysis},
  73 + author = {Megjhani, Murad and Terilli, Kalijah and Kwon, Soon Bin and Nametz, Daniel and Weinerman, Bennett and Velazquez, Angela and Ghoshal, Shivani and Roh, David and Agarwal, Sachin and Connolly, E Sander and others},
  74 + year = 2023,
  75 + journal = {Physiological measurement},
  76 + publisher = {IOP Publishing},
  77 + volume = 44,
  78 + number = 6,
  79 + pages = {064002}
91 80 }
92   -
93 81 %%% contexte clinique%%%
94   -
95 82 @article{tenovuo2021assessing,
96   - title={Assessing the severity of traumatic brain injury—time for a change?},
97   - author={Tenovuo, Olli and Diaz-Arrastia, Ramon and Goldstein, Lee E and Sharp, David J and Van Der Naalt, Joukje and Zasler, Nathan D},
98   - journal={Journal of clinical medicine},
99   - volume={10},
100   - number={1},
101   - pages={148},
102   - year={2021},
103   - publisher={MDPI}
  83 + title = {Assessing the severity of traumatic brain injury—time for a change?},
  84 + author = {Tenovuo, Olli and Diaz-Arrastia, Ramon and Goldstein, Lee E and Sharp, David J and Van Der Naalt, Joukje and Zasler, Nathan D},
  85 + year = 2021,
  86 + journal = {Journal of clinical medicine},
  87 + publisher = {MDPI},
  88 + volume = 10,
  89 + number = 1,
  90 + pages = 148
104 91 }
105   -
106 92 %%% HSA%%%
107   -
108 93 @article{ragaglini2024epidemiology,
109   - title={Epidemiology and treatment of atraumatic subarachnoid hemorrhage over 10 years in a population-based registry},
110   - author={Ragaglini, Chiara and Foschi, Matteo and De Santis, Federico and Molliconi, Anna Laura and Conversi, Francesco and Colangeli, Enrico and Ornello, Raffaele and Sacco, Simona},
111   - journal={European Stroke Journal},
112   - volume={9},
113   - number={1},
114   - pages={200--208},
115   - year={2024},
116   - publisher={SAGE Publications Sage UK: London, England}
  94 + title = {Epidemiology and treatment of atraumatic subarachnoid hemorrhage over 10 years in a population-based registry},
  95 + author = {Ragaglini, Chiara and Foschi, Matteo and De Santis, Federico and Molliconi, Anna Laura and Conversi, Francesco and Colangeli, Enrico and Ornello, Raffaele and Sacco, Simona},
  96 + year = 2024,
  97 + journal = {European Stroke Journal},
  98 + publisher = {SAGE Publications Sage UK: London, England},
  99 + volume = 9,
  100 + number = 1,
  101 + pages = {200--208}
117 102 }
118   -
119 103 @article{lv2024epidemiological,
120   - title={Epidemiological trends of subarachnoid hemorrhage at global, regional, and national level: a trend analysis study from 1990 to 2021},
121   - author={Lv, Bin and Lan, Jin-Xin and Si, Yan-Fang and Ren, Yi-Fan and Li, Ming-Yu and Guo, Fang-Fang and Tang, Ge and Bian, Yang and Wang, Xiao-Hui and Zhang, Rong-Ju and others},
122   - journal={Military Medical Research},
123   - volume={11},
124   - number={1},
125   - pages={46},
126   - year={2024},
127   - publisher={Springer}
  104 + title = {Epidemiological trends of subarachnoid hemorrhage at global, regional, and national level: a trend analysis study from 1990 to 2021},
  105 + author = {Lv, Bin and Lan, Jin-Xin and Si, Yan-Fang and Ren, Yi-Fan and Li, Ming-Yu and Guo, Fang-Fang and Tang, Ge and Bian, Yang and Wang, Xiao-Hui and Zhang, Rong-Ju and others},
  106 + year = 2024,
  107 + journal = {Military Medical Research},
  108 + publisher = {Springer},
  109 + volume = 11,
  110 + number = 1,
  111 + pages = 46
128 112 }
129   -
130 113 @article{sanicola2023pathophysiology,
131   - title={Pathophysiology, management, and therapeutics in subarachnoid hemorrhage and delayed cerebral ischemia: an overview},
132   - author={Sanicola, Henry W and Stewart, Caleb E and Luther, Patrick and Yabut, Kevin and Guthikonda, Bharat and Jordan, J Dedrick and Alexander, J Steven},
133   - journal={Pathophysiology},
134   - volume={30},
135   - number={3},
136   - pages={420--442},
137   - year={2023},
138   - publisher={MDPI}
  114 + title = {Pathophysiology, management, and therapeutics in subarachnoid hemorrhage and delayed cerebral ischemia: an overview},
  115 + author = {Sanicola, Henry W and Stewart, Caleb E and Luther, Patrick and Yabut, Kevin and Guthikonda, Bharat and Jordan, J Dedrick and Alexander, J Steven},
  116 + year = 2023,
  117 + journal = {Pathophysiology},
  118 + publisher = {MDPI},
  119 + volume = 30,
  120 + number = 3,
  121 + pages = {420--442}
139 122 }
140   -
141 123 @article{d2015aneurysmal,
142   - title={Aneurysmal subarachnoid hemorrhage},
143   - author={D’Souza, Stanlies},
144   - journal={Journal of neurosurgical anesthesiology},
145   - volume={27},
146   - number={3},
147   - pages={222--240},
148   - year={2015},
149   - publisher={LWW}
  124 + title = {Aneurysmal subarachnoid hemorrhage},
  125 + author = {D’Souza, Stanlies},
  126 + year = 2015,
  127 + journal = {Journal of neurosurgical anesthesiology},
  128 + publisher = {LWW},
  129 + volume = 27,
  130 + number = 3,
  131 + pages = {222--240}
150 132 }
151   -
152 133 @article{shim2023intracranial,
153   - title={Intracranial pressure monitoring for acute brain injured patients: when, how, what should we monitor},
154   - author={Shim, Youngbo and Kim, Jungook and Kim, Hye Seon and Oh, Jiwoong and Lee, Seungioo and Ha, Eun Jin},
155   - journal={Korean journal of neurotrauma},
156   - volume={19},
157   - number={2},
158   - pages={149},
159   - year={2023},
160   - publisher={Korean Neurotraumatology Society}
  134 + title = {Intracranial pressure monitoring for acute brain injured patients: when, how, what should we monitor},
  135 + author = {Shim, Youngbo and Kim, Jungook and Kim, Hye Seon and Oh, Jiwoong and Lee, Seungioo and Ha, Eun Jin},
  136 + year = 2023,
  137 + journal = {Korean journal of neurotrauma},
  138 + publisher = {Korean Neurotraumatology Society},
  139 + volume = 19,
  140 + number = 2,
  141 + pages = 149
161 142 }
162   -
163 143 %%% monitoring
164 144 @article{lundberg1960continuous,
165   - title={Continuous recording and control of ventricular fluid pressure in neurosurgical practice.},
166   - author={Lundberg, Nils},
167   - journal={Acta Psychiatr Neurol Scand},
168   - volume={36},
169   - pages={1--193},
170   - year={1960}
  145 + title = {Continuous recording and control of ventricular fluid pressure in neurosurgical practice.},
  146 + author = {Lundberg, Nils},
  147 + year = 1960,
  148 + journal = {Acta Psychiatr Neurol Scand},
  149 + volume = 36,
  150 + pages = {1--193}
171 151 }
172   -
173 152 @article{zoerle2024intracranial,
174   - title={Intracranial pressure monitoring in adult patients with traumatic brain injury: challenges and innovations},
175   - author={Zoerle, Tommaso and Beqiri, Erta and {\AA}kerlund, Cecilia AI and Gao, Guoyi and Heldt, Thomas and Hawryluk, Gregory WJ and Stocchetti, Nino},
176   - journal={The Lancet Neurology},
177   - volume={23},
178   - number={9},
179   - pages={938--950},
180   - year={2024},
181   - publisher={Elsevier}
  153 + title = {Intracranial pressure monitoring in adult patients with traumatic brain injury: challenges and innovations},
  154 + author = {Zoerle, Tommaso and Beqiri, Erta and {\AA}kerlund, Cecilia AI and Gao, Guoyi and Heldt, Thomas and Hawryluk, Gregory WJ and Stocchetti, Nino},
  155 + year = 2024,
  156 + journal = {The Lancet Neurology},
  157 + publisher = {Elsevier},
  158 + volume = 23,
  159 + number = 9,
  160 + pages = {938--950}
182 161 }
183   -
184 162 @article{pelah2023accuracy,
185   - title={Accuracy of intracranial pressure monitoring—single centre observational study and literature review},
186   - author={Pelah, Adam I and Zakrzewska, Agnieszka and Calviello, Leanne A and Forcht Dagi, Teodoro and Czosnyka, Zofia and Czosnyka, Marek},
187   - journal={Sensors},
188   - volume={23},
189   - number={7},
190   - pages={3397},
191   - year={2023},
192   - publisher={MDPI}
  163 + title = {Accuracy of intracranial pressure monitoring—single centre observational study and literature review},
  164 + author = {Pelah, Adam I and Zakrzewska, Agnieszka and Calviello, Leanne A and Forcht Dagi, Teodoro and Czosnyka, Zofia and Czosnyka, Marek},
  165 + year = 2023,
  166 + journal = {Sensors},
  167 + publisher = {MDPI},
  168 + volume = 23,
  169 + number = 7,
  170 + pages = 3397
193 171 }
194   -
195 172 @article{tavakoli2017complications,
196   - title={Complications of invasive intracranial pressure monitoring devices in neurocritical care},
197   - author={Tavakoli, Samon and Peitz, Geoffrey and Ares, William and Hafeez, Shaheryar and Grandhi, Ramesh},
198   - journal={Neurosurgical focus},
199   - volume={43},
200   - number={5},
201   - pages={E6},
202   - year={2017},
203   - publisher={American Association of Neurological Surgeons}
  173 + title = {Complications of invasive intracranial pressure monitoring devices in neurocritical care},
  174 + author = {Tavakoli, Samon and Peitz, Geoffrey and Ares, William and Hafeez, Shaheryar and Grandhi, Ramesh},
  175 + year = 2017,
  176 + journal = {Neurosurgical focus},
  177 + publisher = {American Association of Neurological Surgeons},
  178 + volume = 43,
  179 + number = 5,
  180 + pages = {E6}
204 181 }
205   -
206 182 @article{akbik2016roles,
207   - title={The roles of ventricular and parenchymal intracranial pressure monitoring},
208   - author={Akbik, Omar S and Carlson, Andrew P and Yonas, Howard},
209   - journal={Curr. Neurobiol},
210   - volume={7},
211   - pages={1--6},
212   - year={2016}
  183 + title = {The roles of ventricular and parenchymal intracranial pressure monitoring},
  184 + author = {Akbik, Omar S and Carlson, Andrew P and Yonas, Howard},
  185 + year = 2016,
  186 + journal = {Curr. Neurobiol},
  187 + volume = 7,
  188 + pages = {1--6}
213 189 }
214 190 %%%
215   -
216 191 @article{weed1929some,
217   - title={Some limitations of the Monro-Kellie hypothesis},
218   - author={Weed, Lewis H},
219   - journal={Archives of Surgery},
220   - volume={18},
221   - number={4},
222   - pages={1049--1068},
223   - year={1929},
224   - publisher={American Medical Association}
  192 + title = {Some limitations of the Monro-Kellie hypothesis},
  193 + author = {Weed, Lewis H},
  194 + year = 1929,
  195 + journal = {Archives of Surgery},
  196 + publisher = {American Medical Association},
  197 + volume = 18,
  198 + number = 4,
  199 + pages = {1049--1068}
225 200 }
226   -
227 201 @article{carney2017guidelines,
228   - title={Guidelines for the management of severe traumatic brain injury},
229   - author={Carney, Nancy and Totten, Annette M and O'Reilly, Cindy and Ullman, Jamie S and Hawryluk, Gregory WJ and Bell, Michael J and Bratton, Susan L and Chesnut, Randall and Harris, Odette A and Kissoon, Niranjan and others},
230   - journal={Neurosurgery},
231   - volume={80},
232   - number={1},
233   - pages={6--15},
234   - year={2017},
235   - publisher={LWW}
  202 + title = {Guidelines for the management of severe traumatic brain injury},
  203 + author = {Carney, Nancy and Totten, Annette M and O'Reilly, Cindy and Ullman, Jamie S and Hawryluk, Gregory WJ and Bell, Michael J and Bratton, Susan L and Chesnut, Randall and Harris, Odette A and Kissoon, Niranjan and others},
  204 + year = 2017,
  205 + journal = {Neurosurgery},
  206 + publisher = {LWW},
  207 + volume = 80,
  208 + number = 1,
  209 + pages = {6--15}
236 210 }
237   -
238 211 @article{cnossen2016variation,
239   - title={Variation in structure and process of care in traumatic brain injury: provider profiles of European neurotrauma centers participating in the CENTER-TBI study},
240   - author={Cnossen, Maryse C and Polinder, Suzanne and Lingsma, Hester F and Maas, Andrew IR and Menon, David and Steyerberg, Ewout W and CENTER-TBI Investigators and Participants},
241   - journal={Plos one},
242   - volume={11},
243   - number={8},
244   - pages={e0161367},
245   - year={2016},
246   - publisher={Public Library of Science San Francisco, CA USA}
  212 + title = {Variation in structure and process of care in traumatic brain injury: provider profiles of European neurotrauma centers participating in the CENTER-TBI study},
  213 + author = {Cnossen, Maryse C and Polinder, Suzanne and Lingsma, Hester F and Maas, Andrew IR and Menon, David and Steyerberg, Ewout W and CENTER-TBI Investigators and Participants},
  214 + year = 2016,
  215 + journal = {Plos one},
  216 + publisher = {Public Library of Science San Francisco, CA USA},
  217 + volume = 11,
  218 + number = 8,
  219 + pages = {e0161367}
247 220 }
248   -
249 221 @article{stein2023associations,
250   - title={Associations between intracranial pressure thresholds and multimodal monitoring in acute traumatic neural injury: a scoping review},
251   - author={Stein, Kevin Y and Amenta, Fiorella and Gomez, Alwyn and Froese, Logan and Sainbhi, Amanjyot Singh and Vakitbilir, Nuray and Marquez, Izabella and Zeiler, Frederick A},
252   - journal={Acta Neurochirurgica},
253   - volume={165},
254   - number={7},
255   - pages={1987--2000},
256   - year={2023},
257   - publisher={Springer}
  222 + title = {Associations between intracranial pressure thresholds and multimodal monitoring in acute traumatic neural injury: a scoping review},
  223 + author = {Stein, Kevin Y and Amenta, Fiorella and Gomez, Alwyn and Froese, Logan and Sainbhi, Amanjyot Singh and Vakitbilir, Nuray and Marquez, Izabella and Zeiler, Frederick A},
  224 + year = 2023,
  225 + journal = {Acta Neurochirurgica},
  226 + publisher = {Springer},
  227 + volume = 165,
  228 + number = 7,
  229 + pages = {1987--2000}
258 230 }
259   -
260 231 @article{aakerlund2020impact,
261   - title={Impact of duration and magnitude of raised intracranial pressure on outcome after severe traumatic brain injury: a CENTER-TBI high-resolution group study},
262   - author={{\AA}kerlund, Cecilia AI and Donnelly, Joseph and Zeiler, Frederick A and Helbok, Raimund and Holst, Anders and Cabeleira, Manuel and G{\"u}iza, Fabian and Meyfroidt, Geert and Czosnyka, Marek and Smielewski, Peter and others},
263   - journal={PloS one},
264   - volume={15},
265   - number={12},
266   - pages={e0243427},
267   - year={2020},
268   - publisher={Public Library of Science San Francisco, CA USA}
  232 + title = {Impact of duration and magnitude of raised intracranial pressure on outcome after severe traumatic brain injury: a CENTER-TBI high-resolution group study},
  233 + author = {{\AA}kerlund, Cecilia AI and Donnelly, Joseph and Zeiler, Frederick A and Helbok, Raimund and Holst, Anders and Cabeleira, Manuel and G{\"u}iza, Fabian and Meyfroidt, Geert and Czosnyka, Marek and Smielewski, Peter and others},
  234 + year = 2020,
  235 + journal = {PloS one},
  236 + publisher = {Public Library of Science San Francisco, CA USA},
  237 + volume = 15,
  238 + number = 12,
  239 + pages = {e0243427}
269 240 }
270   -
271 241 @article{schonenberg2023pressure,
272   - title={Pressure time dose as a representation of intracranial pressure burden and its dependency on intracranial pressure waveform morphology at different time intervals},
273   - author={Sch{\"o}nenberg-Tu, Anna-Li and Cysarz, Dirk and Petzold, Benjamin and Bl{\"u}mel, Carl Benjamin and Raak, Christa and Fricke, Oliver and Edelh{\"a}user, Friedrich and Scharbrodt, Wolfram},
274   - journal={Sensors},
275   - volume={23},
276   - number={19},
277   - pages={8051},
278   - year={2023},
279   - publisher={MDPI}
  242 + title = {Pressure time dose as a representation of intracranial pressure burden and its dependency on intracranial pressure waveform morphology at different time intervals},
  243 + author = {Sch{\"o}nenberg-Tu, Anna-Li and Cysarz, Dirk and Petzold, Benjamin and Bl{\"u}mel, Carl Benjamin and Raak, Christa and Fricke, Oliver and Edelh{\"a}user, Friedrich and Scharbrodt, Wolfram},
  244 + year = 2023,
  245 + journal = {Sensors},
  246 + publisher = {MDPI},
  247 + volume = 23,
  248 + number = 19,
  249 + pages = 8051
280 250 }
281   -
282 251 @article{czosnyka2007intracranial,
283   - title={Intracranial pressure: more than a number},
284   - author={Czosnyka, Marek and Smielewski, Peter and Timofeev, Ivan and Lavinio, Andrea and Guazzo, Eric and Hutchinson, Peter and Pickard, John D},
285   - journal={Neurosurgical focus},
286   - volume={22},
287   - number={5},
288   - pages={1--7},
289   - year={2007},
290   - publisher={American Association of Neurological Surgeons}
  252 + title = {Intracranial pressure: more than a number},
  253 + author = {Czosnyka, Marek and Smielewski, Peter and Timofeev, Ivan and Lavinio, Andrea and Guazzo, Eric and Hutchinson, Peter and Pickard, John D},
  254 + year = 2007,
  255 + journal = {Neurosurgical focus},
  256 + publisher = {American Association of Neurological Surgeons},
  257 + volume = 22,
  258 + number = 5,
  259 + pages = {1--7}
291 260 }
292   -
293 261 @article{dai2020intracranial,
294   - title={Intracranial pressure monitoring signals after traumatic brain injury: a narrative overview and conceptual data science framework},
295   - author={Dai, Honghao and Jia, Xiaodong and Pahren, Laura and Lee, Jay and Foreman, Brandon},
296   - journal={Frontiers in neurology},
297   - volume={11},
298   - pages={959},
299   - year={2020},
300   - publisher={Frontiers Media SA}
  262 + title = {Intracranial pressure monitoring signals after traumatic brain injury: a narrative overview and conceptual data science framework},
  263 + author = {Dai, Honghao and Jia, Xiaodong and Pahren, Laura and Lee, Jay and Foreman, Brandon},
  264 + year = 2020,
  265 + journal = {Frontiers in neurology},
  266 + publisher = {Frontiers Media SA},
  267 + volume = 11,
  268 + pages = 959
301 269 }
302   -
303 270 @article{lundberg1965continuous,
304   - title={Continuous recording of the ventricular-fluid pressure in patients with severe acute traumatic brain injury: a preliminary report},
305   - author={Lundberg, Nils and Troupp, Henry and Lorin, Henry},
306   - journal={Journal of neurosurgery},
307   - volume={22},
308   - number={6},
309   - pages={581--590},
310   - year={1965},
311   - publisher={Journal of Neurosurgery Publishing Group}
  271 + title = {Continuous recording of the ventricular-fluid pressure in patients with severe acute traumatic brain injury: a preliminary report},
  272 + author = {Lundberg, Nils and Troupp, Henry and Lorin, Henry},
  273 + year = 1965,
  274 + journal = {Journal of neurosurgery},
  275 + publisher = {Journal of Neurosurgery Publishing Group},
  276 + volume = 22,
  277 + number = 6,
  278 + pages = {581--590}
312 279 }
313   -
314 280 @article{rosner1984origin,
315   - title={Origin and evolution of plateau waves: experimental observations and a theoretical model},
316   - author={Rosner, Michael J and Becker, Donald P},
317   - journal={Journal of neurosurgery},
318   - volume={60},
319   - number={2},
320   - pages={312--324},
321   - year={1984},
322   - publisher={Journal of Neurosurgery Publishing Group}
  281 + title = {Origin and evolution of plateau waves: experimental observations and a theoretical model},
  282 + author = {Rosner, Michael J and Becker, Donald P},
  283 + year = 1984,
  284 + journal = {Journal of neurosurgery},
  285 + publisher = {Journal of Neurosurgery Publishing Group},
  286 + volume = 60,
  287 + number = 2,
  288 + pages = {312--324}
323 289 }
324   -
325 290 @article{castellani2009plateau,
326   - title={Plateau waves in head injured patients requiring neurocritical care},
327   - author={Castellani, Gianluca and Zweifel, Christian and Kim, Dong-Joo and Carrera, Emmanuel and Radolovich, Danila K and Smielewski, Piotr and Hutchinson, Peter J and Pickard, John D and Czosnyka, Marek},
328   - journal={Neurocritical care},
329   - volume={11},
330   - pages={143--150},
331   - year={2009},
332   - publisher={Springer}
  291 + title = {Plateau waves in head injured patients requiring neurocritical care},
  292 + author = {Castellani, Gianluca and Zweifel, Christian and Kim, Dong-Joo and Carrera, Emmanuel and Radolovich, Danila K and Smielewski, Piotr and Hutchinson, Peter J and Pickard, John D and Czosnyka, Marek},
  293 + year = 2009,
  294 + journal = {Neurocritical care},
  295 + publisher = {Springer},
  296 + volume = 11,
  297 + pages = {143--150}
333 298 }
334   -
335 299 %%% B-waves%%%
336 300 @article{martinez2019b,
337   - title={B waves: a systematic review of terminology, characteristics, and analysis methods},
338   - author={Martinez-Tejada, Isabel and Arum, Alexander and Wilhjelm, Jens E and Juhler, Marianne and Andresen, Morten},
339   - journal={Fluids and Barriers of the CNS},
340   - volume={16},
341   - pages={1--15},
342   - year={2019},
343   - publisher={Springer}
  301 + title = {B waves: a systematic review of terminology, characteristics, and analysis methods},
  302 + author = {Martinez-Tejada, Isabel and Arum, Alexander and Wilhjelm, Jens E and Juhler, Marianne and Andresen, Morten},
  303 + year = 2019,
  304 + journal = {Fluids and Barriers of the CNS},
  305 + publisher = {Springer},
  306 + volume = 16,
  307 + pages = {1--15}
344 308 }
345   -
346 309 @article{raftopoulos1992morphological,
347   - title={Morphological quantitative analysis of intracranial pressure waves in normal pressure hydrocephalus},
348   - author={Raftopoulos, Christian and Chaskis, Christo and Delecluse, Florence and Cantrainet, Francis and Bidauti, Luc and Brotchi, Jacques},
349   - journal={Neurological research},
350   - volume={14},
351   - number={5},
352   - pages={389--396},
353   - year={1992},
354   - publisher={Taylor \& Francis}
  310 + title = {Morphological quantitative analysis of intracranial pressure waves in normal pressure hydrocephalus},
  311 + author = {Raftopoulos, Christian and Chaskis, Christo and Delecluse, Florence and Cantrainet, Francis and Bidauti, Luc and Brotchi, Jacques},
  312 + year = 1992,
  313 + journal = {Neurological research},
  314 + publisher = {Taylor \& Francis},
  315 + volume = 14,
  316 + number = 5,
  317 + pages = {389--396}
355 318 }
356   -
357 319 @article{santamarta2016prediction,
358   - title={The prediction of shunt response in idiopathic normal-pressure hydrocephalus based on intracranial pressure monitoring and lumbar infusion},
359   - author={Santamarta, David and Gonz{\'a}lez-Mart{\'\i}nez, E and Fern{\'a}ndez, J and Mostaza, A},
360   - journal={Intracranial Pressure and Brain Monitoring XV},
361   - pages={267--274},
362   - year={2016},
363   - publisher={Springer}
  320 + title = {The prediction of shunt response in idiopathic normal-pressure hydrocephalus based on intracranial pressure monitoring and lumbar infusion},
  321 + author = {Santamarta, David and Gonz{\'a}lez-Mart{\'\i}nez, E and Fern{\'a}ndez, J and Mostaza, A},
  322 + year = 2016,
  323 + journal = {Intracranial Pressure and Brain Monitoring XV},
  324 + publisher = {Springer},
  325 + pages = {267--274}
364 326 }
365   -
366   -
367 327 @article{yokota1989overnight,
368   - title={Overnight Recordings of Intracranial Pressure and Electroencephalography in Neurosurgical Patients Part1: Intracranial Pressure Waves and Their Clinical Correlations},
369   - author={YOKOTA, Akira and MATSUOKA, Shigeaki and ISHIKAWA, Tadahiro and KOHSHI, Kiyotaka and KAJIWARA, Hidehiko},
370   - journal={Journal of UOEH},
371   - volume={11},
372   - number={4},
373   - pages={371--381},
374   - year={1989},
375   - publisher={The University of Occupational and Environmental Health, Japan}
  328 + title = {Overnight Recordings of Intracranial Pressure and Electroencephalography in Neurosurgical Patients Part1: Intracranial Pressure Waves and Their Clinical Correlations},
  329 + author = {YOKOTA, Akira and MATSUOKA, Shigeaki and ISHIKAWA, Tadahiro and KOHSHI, Kiyotaka and KAJIWARA, Hidehiko},
  330 + year = 1989,
  331 + journal = {Journal of UOEH},
  332 + publisher = {The University of Occupational and Environmental Health, Japan},
  333 + volume = 11,
  334 + number = 4,
  335 + pages = {371--381}
376 336 }
377   -
378 337 @book{kasprowicz2012association,
379   - title={Association between ICP pulse waveform morphology and ICP B waves},
380   - author={Kasprowicz, Magdalena and Bergsneider, Marvin and Czosnyka, Marek and Hu, Xiao},
381   - year={2012},
382   - publisher={Springer}
  338 + title = {Association between ICP pulse waveform morphology and ICP B waves},
  339 + author = {Kasprowicz, Magdalena and Bergsneider, Marvin and Czosnyka, Marek and Hu, Xiao},
  340 + year = 2012,
  341 + publisher = {Springer}
383 342 }
384   -
385 343 @article{riedel2021b,
386   - title={B-waves are present in patients without intracranial pressure disturbances},
387   - author={Riedel, Casper Schwartz and Martinez-Tejada, Isabel and Norager, Nicolas Hernandez and Kempfner, Lykke and Jennum, Poul and Juhler, Marianne},
388   - journal={Journal of Sleep Research},
389   - volume={30},
390   - number={4},
391   - pages={e13214},
392   - year={2021},
393   - publisher={Wiley Online Library}
  344 + title = {B-waves are present in patients without intracranial pressure disturbances},
  345 + author = {Riedel, Casper Schwartz and Martinez-Tejada, Isabel and Norager, Nicolas Hernandez and Kempfner, Lykke and Jennum, Poul and Juhler, Marianne},
  346 + year = 2021,
  347 + journal = {Journal of Sleep Research},
  348 + publisher = {Wiley Online Library},
  349 + volume = 30,
  350 + number = 4,
  351 + pages = {e13214}
394 352 }
395   -
396 353 @article{riedel2023transient,
397   - title={Transient intracranial pressure elevations (B waves) are associated with sleep apnea},
398   - author={Riedel, Casper Schwartz and Martinez-Tejada, Isabel and Andresen, Morten and Wilhjelm, Jens E and Jennum, Poul and Juhler, Marianne},
399   - journal={Fluids and Barriers of the CNS},
400   - volume={20},
401   - number={1},
402   - pages={69},
403   - year={2023},
404   - publisher={Springer}
  354 + title = {Transient intracranial pressure elevations (B waves) are associated with sleep apnea},
  355 + author = {Riedel, Casper Schwartz and Martinez-Tejada, Isabel and Andresen, Morten and Wilhjelm, Jens E and Jennum, Poul and Juhler, Marianne},
  356 + year = 2023,
  357 + journal = {Fluids and Barriers of the CNS},
  358 + publisher = {Springer},
  359 + volume = 20,
  360 + number = 1,
  361 + pages = 69
405 362 }
406   -
407 363 @article{spiegelberg2016b,
408   - title={B-waves revisited},
409   - author={Spiegelberg, Andreas and Preu{\ss}, Matthias and Kurtcuoglu, Vartan},
410   - journal={Interdisciplinary Neurosurgery},
411   - volume={6},
412   - pages={13--17},
413   - year={2016},
414   - publisher={Elsevier}
  364 + title = {B-waves revisited},
  365 + author = {Spiegelberg, Andreas and Preu{\ss}, Matthias and Kurtcuoglu, Vartan},
  366 + year = 2016,
  367 + journal = {Interdisciplinary Neurosurgery},
  368 + publisher = {Elsevier},
  369 + volume = 6,
  370 + pages = {13--17}
415 371 }
416   -
417 372 @article{beqiri2020influence,
418   - title={Influence of mild-moderate hypocapnia on intracranial pressure slow waves activity in TBI},
419   - author={Beqiri, Erta and Czosnyka, Marek and Lalou, Afroditi D and Zeiler, Frederick A and Fedriga, Marta and Steiner, Luzius A and Chieregato, Arturo and Smielewski, Peter},
420   - journal={Acta neurochirurgica},
421   - volume={162},
422   - pages={345--356},
423   - year={2020},
424   - publisher={Springer}
  373 + title = {Influence of mild-moderate hypocapnia on intracranial pressure slow waves activity in TBI},
  374 + author = {Beqiri, Erta and Czosnyka, Marek and Lalou, Afroditi D and Zeiler, Frederick A and Fedriga, Marta and Steiner, Luzius A and Chieregato, Arturo and Smielewski, Peter},
  375 + year = 2020,
  376 + journal = {Acta neurochirurgica},
  377 + publisher = {Springer},
  378 + volume = 162,
  379 + pages = {345--356}
425 380 }
426   -
427 381 @article{mautner1989b,
428   - title={B-waves in healthy persons},
429   - author={Mautner-Huppert, Doreen and Haberl, Roman L and Dirnagl, Ulrich and Villringer, Arno and Schmiedek, Peter and Einhaupl, Karl},
430   - journal={Neurological research},
431   - volume={11},
432   - number={4},
433   - pages={194--196},
434   - year={1989},
435   - publisher={Taylor \& Francis}
  382 + title = {B-waves in healthy persons},
  383 + author = {Mautner-Huppert, Doreen and Haberl, Roman L and Dirnagl, Ulrich and Villringer, Arno and Schmiedek, Peter and Einhaupl, Karl},
  384 + year = 1989,
  385 + journal = {Neurological research},
  386 + publisher = {Taylor \& Francis},
  387 + volume = 11,
  388 + number = 4,
  389 + pages = {194--196}
436 390 }
437   -
438 391 @article{newell2022physiological,
439   - title={Physiological mechanisms and significance of intracranial B waves},
440   - author={Newell, David W and Nedergaard, Maiken and Aaslid, Rune},
441   - journal={Frontiers in neurology},
442   - volume={13},
443   - pages={872701},
444   - year={2022},
445   - publisher={Frontiers Media SA}
  392 + title = {Physiological mechanisms and significance of intracranial B waves},
  393 + author = {Newell, David W and Nedergaard, Maiken and Aaslid, Rune},
  394 + year = 2022,
  395 + journal = {Frontiers in neurology},
  396 + publisher = {Frontiers Media SA},
  397 + volume = 13,
  398 + pages = 872701
446 399 }
447   -
448 400 @article{julien2006enigma,
449   - title={The enigma of Mayer waves: facts and models},
450   - author={Julien, Claude},
451   - journal={Cardiovascular research},
452   - volume={70},
453   - number={1},
454   - pages={12--21},
455   - year={2006},
456   - publisher={Elsevier Science}
  401 + title = {The enigma of Mayer waves: facts and models},
  402 + author = {Julien, Claude},
  403 + year = 2006,
  404 + journal = {Cardiovascular research},
  405 + publisher = {Elsevier Science},
  406 + volume = 70,
  407 + number = 1,
  408 + pages = {12--21}
457 409 }
458   -
459 410 @article{hickey2009intracranial,
460   - title={Intracranial pressure waveform analysis during rest and suctioning},
461   - author={Hickey, Joanne V and Olson, DaiWai M and Turner, Dennis A},
462   - journal={Biological research for nursing},
463   - volume={11},
464   - number={2},
465   - pages={174--186},
466   - year={2009},
467   - publisher={SAGE Publications Sage CA: Los Angeles, CA}
  411 + title = {Intracranial pressure waveform analysis during rest and suctioning},
  412 + author = {Hickey, Joanne V and Olson, DaiWai M and Turner, Dennis A},
  413 + year = 2009,
  414 + journal = {Biological research for nursing},
  415 + publisher = {SAGE Publications Sage CA: Los Angeles, CA},
  416 + volume = 11,
  417 + number = 2,
  418 + pages = {174--186}
468 419 }
469   -
470 420 @article{foltz1990csf,
471   - title={CSF pulsatility in hydrocephalus: respiratory effect on pulse wave slope as an indicator of intracranial compliance},
472   - author={Foltz, Eldon L and Blanks, Jeff P and Yonemura, Kenneth},
473   - journal={Neurological research},
474   - volume={12},
475   - number={2},
476   - pages={67--74},
477   - year={1990},
478   - publisher={Taylor \& Francis}
  421 + title = {CSF pulsatility in hydrocephalus: respiratory effect on pulse wave slope as an indicator of intracranial compliance},
  422 + author = {Foltz, Eldon L and Blanks, Jeff P and Yonemura, Kenneth},
  423 + year = 1990,
  424 + journal = {Neurological research},
  425 + publisher = {Taylor \& Francis},
  426 + volume = 12,
  427 + number = 2,
  428 + pages = {67--74}
479 429 }
480   -
481 430 @article{germon1994intracranial,
482   - title={Intracranial pressure monitoring in the 1990s},
483   - author={Germon, Karin},
484   - journal={Critical Care Nursing Quarterly},
485   - volume={17},
486   - number={1},
487   - pages={21--32},
488   - year={1994},
489   - publisher={LWW}
  431 + title = {Intracranial pressure monitoring in the 1990s},
  432 + author = {Germon, Karin},
  433 + year = 1994,
  434 + journal = {Critical Care Nursing Quarterly},
  435 + publisher = {LWW},
  436 + volume = 17,
  437 + number = 1,
  438 + pages = {21--32}
490 439 }
491   -
492 440 @article{czosnyka2020origin,
493   - title={Origin of intracranial pressure pulse waveform},
494   - author={Czosnyka, Marek and Czosnyka, Zofia},
495   - journal={Acta Neurochirurgica},
496   - volume={162},
497   - pages={1815--1817},
498   - year={2020},
499   - publisher={Springer}
  441 + title = {Origin of intracranial pressure pulse waveform},
  442 + author = {Czosnyka, Marek and Czosnyka, Zofia},
  443 + year = 2020,
  444 + journal = {Acta Neurochirurgica},
  445 + publisher = {Springer},
  446 + volume = 162,
  447 + pages = {1815--1817}
500 448 }
501   -
502 449 @article{unnerback2018icp,
503   - title={ICP curve morphology and intracranial flow-volume changes: a simultaneous ICP and cine phase contrast MRI study in humans},
504   - author={Unnerb{\"a}ck, M{\aa}rten and Ottesen, Johnny T and Reinstrup, Peter},
505   - journal={Acta neurochirurgica},
506   - volume={160},
507   - pages={219--224},
508   - year={2018},
509   - publisher={Springer}
  450 + title = {ICP curve morphology and intracranial flow-volume changes: a simultaneous ICP and cine phase contrast MRI study in humans},
  451 + author = {Unnerb{\"a}ck, M{\aa}rten and Ottesen, Johnny T and Reinstrup, Peter},
  452 + year = 2018,
  453 + journal = {Acta neurochirurgica},
  454 + publisher = {Springer},
  455 + volume = 160,
  456 + pages = {219--224}
510 457 }
511   -
512 458 @article{ziolkowski2021analysis,
513   - title={Analysis of relative changes in pulse shapes of intracranial pressure and cerebral blood flow velocity},
514   - author={Zi{\'o}{\l}kowski, Arkadiusz and Pude{\l}ko, Agata and Kazimierska, Agnieszka and Czosnyka, Zofia and Czosnyka, Marek and Kasprowicz, Magdalena},
515   - journal={Physiological Measurement},
516   - volume={42},
517   - number={12},
518   - pages={125004},
519   - year={2021},
520   - publisher={IOP Publishing}
  459 + title = {Analysis of relative changes in pulse shapes of intracranial pressure and cerebral blood flow velocity},
  460 + author = {Zi{\'o}{\l}kowski, Arkadiusz and Pude{\l}ko, Agata and Kazimierska, Agnieszka and Czosnyka, Zofia and Czosnyka, Marek and Kasprowicz, Magdalena},
  461 + year = 2021,
  462 + journal = {Physiological Measurement},
  463 + publisher = {IOP Publishing},
  464 + volume = 42,
  465 + number = 12,
  466 + pages = 125004
521 467 }
522   -
523 468 @article{ziolkowski2023peak,
524   - title={Peak appearance time in pulse waveforms of intracranial pressure and cerebral blood flow velocity},
525   - author={Zi{\'o}{\l}kowski, Arkadiusz and Pude{\l}ko, Agata and Kazimierska, Agnieszka and Uryga, Agnieszka and Czosnyka, Zofia and Kasprowicz, Magdalena and Czosnyka, Marek},
526   - journal={Frontiers in Physiology},
527   - volume={13},
528   - pages={1077966},
529   - year={2023},
530   - publisher={Frontiers Media SA}
  469 + title = {Peak appearance time in pulse waveforms of intracranial pressure and cerebral blood flow velocity},
  470 + author = {Zi{\'o}{\l}kowski, Arkadiusz and Pude{\l}ko, Agata and Kazimierska, Agnieszka and Uryga, Agnieszka and Czosnyka, Zofia and Kasprowicz, Magdalena and Czosnyka, Marek},
  471 + year = 2023,
  472 + journal = {Frontiers in Physiology},
  473 + publisher = {Frontiers Media SA},
  474 + volume = 13,
  475 + pages = 1077966
531 476 }
532   -
533 477 @article{carrera2010shapes,
534   - title={What shapes pulse amplitude of intracranial pressure?},
535   - author={Carrera, Emmanuel and Kim, Dong-Joo and Castellani, Gianluca and Zweifel, Christian and Czosnyka, Zofia and Kasprowicz, Magdalena and Smielewski, Peter and Pickard, John D and Czosnyka, Marek},
536   - journal={Journal of neurotrauma},
537   - volume={27},
538   - number={2},
539   - pages={317--324},
540   - year={2010},
541   - publisher={Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA}
  478 + title = {What shapes pulse amplitude of intracranial pressure?},
  479 + author = {Carrera, Emmanuel and Kim, Dong-Joo and Castellani, Gianluca and Zweifel, Christian and Czosnyka, Zofia and Kasprowicz, Magdalena and Smielewski, Peter and Pickard, John D and Czosnyka, Marek},
  480 + year = 2010,
  481 + journal = {Journal of neurotrauma},
  482 + publisher = {Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA},
  483 + volume = 27,
  484 + number = 2,
  485 + pages = {317--324}
542 486 }
543   -
544 487 @article{domogo2023mechanistic,
545   - title={Mechanistic-mathematical modeling of intracranial pressure (ICP) profiles over a single heart cycle. The fundament of the ICP curve form},
546   - author={Domogo, Andrei A and Reinstrup, Peter and Ottesen, Johnny T},
547   - journal={Journal of Theoretical Biology},
548   - volume={564},
549   - pages={111451},
550   - year={2023},
551   - publisher={Elsevier}
  488 + title = {Mechanistic-mathematical modeling of intracranial pressure (ICP) profiles over a single heart cycle. The fundament of the ICP curve form},
  489 + author = {Domogo, Andrei A and Reinstrup, Peter and Ottesen, Johnny T},
  490 + year = 2023,
  491 + journal = {Journal of Theoretical Biology},
  492 + publisher = {Elsevier},
  493 + volume = 564,
  494 + pages = 111451
552 495 }
553   -
554   -
555 496 %%% signal %%%
556   -
557   -
558 497 @article{ge2018theoretical,
559   - title={Theoretical analysis of empirical mode decomposition},
560   - author={Ge, Hengqing and Chen, Guibin and Yu, Haichun and Chen, Huabao and An, Fengping},
561   - journal={Symmetry},
562   - volume={10},
563   - number={11},
564   - pages={623},
565   - year={2018},
566   - publisher={MDPI}
  498 + title = {Theoretical analysis of empirical mode decomposition},
  499 + author = {Ge, Hengqing and Chen, Guibin and Yu, Haichun and Chen, Huabao and An, Fengping},
  500 + year = 2018,
  501 + journal = {Symmetry},
  502 + publisher = {MDPI},
  503 + volume = 10,
  504 + number = 11,
  505 + pages = 623
567 506 }
568   -
569 507 @article{barbosh2020empirical,
570   - title={Empirical mode decomposition and its variants: A review with applications in structural health monitoring},
571   - author={Barbosh, Mohamed and Singh, Premjeet and Sadhu, Ayan},
572   - journal={Smart Materials and Structures},
573   - volume={29},
574   - number={9},
575   - pages={093001},
576   - year={2020},
577   - publisher={IOP Publishing}
  508 + title = {Empirical mode decomposition and its variants: A review with applications in structural health monitoring},
  509 + author = {Barbosh, Mohamed and Singh, Premjeet and Sadhu, Ayan},
  510 + year = 2020,
  511 + journal = {Smart Materials and Structures},
  512 + publisher = {IOP Publishing},
  513 + volume = 29,
  514 + number = 9,
  515 + pages = {093001}
578 516 }
579   -
580 517 @article{chen2022seismic,
581   - title={Seismic time-frequency analysis via time-varying filtering based empirical mode decomposition method},
582   - author={Chen, Siyuan and Cao, Siyuan and Sun, Yaoguang and Lin, Ying and Gao, Jun},
583   - journal={Journal of Applied Geophysics},
584   - volume={204},
585   - pages={104731},
586   - year={2022},
587   - publisher={Elsevier}
  518 + title = {Seismic time-frequency analysis via time-varying filtering based empirical mode decomposition method},
  519 + author = {Chen, Siyuan and Cao, Siyuan and Sun, Yaoguang and Lin, Ying and Gao, Jun},
  520 + year = 2022,
  521 + journal = {Journal of Applied Geophysics},
  522 + publisher = {Elsevier},
  523 + volume = 204,
  524 + pages = 104731
588 525 }
589   -
590 526 @article{munoz2018localization,
591   - title={Localization of active brain sources from EEG signals using empirical mode decomposition: a comparative study},
592   - author={Mu{\~n}oz-Guti{\'e}rrez, Pablo Andr{\'e}s and Giraldo, Eduardo and Bueno-L{\'o}pez, Maximiliano and Molinas, Marta},
593   - journal={Frontiers in integrative neuroscience},
594   - volume={12},
595   - pages={55},
596   - year={2018},
597   - publisher={Frontiers Media SA}
  527 + title = {Localization of active brain sources from EEG signals using empirical mode decomposition: a comparative study},
  528 + author = {Mu{\~n}oz-Guti{\'e}rrez, Pablo Andr{\'e}s and Giraldo, Eduardo and Bueno-L{\'o}pez, Maximiliano and Molinas, Marta},
  529 + year = 2018,
  530 + journal = {Frontiers in integrative neuroscience},
  531 + publisher = {Frontiers Media SA},
  532 + volume = 12,
  533 + pages = 55
598 534 }
599   -
600 535 @incollection{martinez2021empirical,
601   - title={Empirical mode decomposition-based method for artefact removal in raw intracranial pressure signals},
602   - author={Martinez-Tejada, Isabel and Wilhjelm, Jens E and Juhler, Marianne and Andresen, Morten},
603   - booktitle={Intracranial Pressure and Neuromonitoring XVII},
604   - pages={201--205},
605   - year={2021},
606   - publisher={Springer}
  536 + title = {Empirical mode decomposition-based method for artefact removal in raw intracranial pressure signals},
  537 + author = {Martinez-Tejada, Isabel and Wilhjelm, Jens E and Juhler, Marianne and Andresen, Morten},
  538 + year = 2021,
  539 + booktitle = {Intracranial Pressure and Neuromonitoring XVII},
  540 + publisher = {Springer},
  541 + pages = {201--205}
607 542 }
608   -
609 543 @article{rilling2007one,
610   - title={One or two frequencies? The empirical mode decomposition answers},
611   - author={Rilling, Gabriel and Flandrin, Patrick},
612   - journal={IEEE transactions on signal processing},
613   - volume={56},
614   - number={1},
615   - pages={85--95},
616   - year={2007},
617   - publisher={IEEE}
  544 + title = {One or two frequencies? The empirical mode decomposition answers},
  545 + author = {Rilling, Gabriel and Flandrin, Patrick},
  546 + year = 2007,
  547 + journal = {IEEE transactions on signal processing},
  548 + publisher = {IEEE},
  549 + volume = 56,
  550 + number = 1,
  551 + pages = {85--95}
618 552 }
619   -
620 553 @inproceedings{xu2016study,
621   - title={Study on mode mixing problem of empirical mode decomposition},
622   - author={Xu, Guimin and Yang, Zhengxiang and Wang, Sha},
623   - booktitle={2016 Joint International Information Technology, Mechanical and Electronic Engineering Conference},
624   - pages={389--394},
625   - year={2016},
626   - organization={Atlantis Press}
  554 + title = {Study on mode mixing problem of empirical mode decomposition},
  555 + author = {Xu, Guimin and Yang, Zhengxiang and Wang, Sha},
  556 + year = 2016,
  557 + booktitle = {2016 Joint International Information Technology, Mechanical and Electronic Engineering Conference},
  558 + pages = {389--394},
  559 + organization = {Atlantis Press}
627 560 }
628   -
629 561 @article{huang2003confidence,
630   - title={A confidence limit for the empirical mode decomposition and Hilbert spectral analysis},
631   - author={Huang, Norden E and Wu, Man-Li C and Long, Steven R and Shen, Samuel SP and Qu, Wendong and Gloersen, Per and Fan, Kuang L},
632   - journal={Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences},
633   - volume={459},
634   - number={2037},
635   - pages={2317--2345},
636   - year={2003},
637   - publisher={The Royal Society}
  562 + title = {A confidence limit for the empirical mode decomposition and Hilbert spectral analysis},
  563 + author = {Huang, Norden E and Wu, Man-Li C and Long, Steven R and Shen, Samuel SP and Qu, Wendong and Gloersen, Per and Fan, Kuang L},
  564 + year = 2003,
  565 + journal = {Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences},
  566 + publisher = {The Royal Society},
  567 + volume = 459,
  568 + number = 2037,
  569 + pages = {2317--2345}
638 570 }
639   -
640 571 @article{zare2023end,
641   - title={End-effects mitigation in empirical mode decomposition using a new correlation-based expansion model},
642   - author={Zare, Mehdi and Nouri, Nowrouz Mohammad},
643   - journal={Mechanical Systems and Signal Processing},
644   - volume={194},
645   - pages={110205},
646   - year={2023},
647   - publisher={Elsevier}
  572 + title = {End-effects mitigation in empirical mode decomposition using a new correlation-based expansion model},
  573 + author = {Zare, Mehdi and Nouri, Nowrouz Mohammad},
  574 + year = 2023,
  575 + journal = {Mechanical Systems and Signal Processing},
  576 + publisher = {Elsevier},
  577 + volume = 194,
  578 + pages = 110205
648 579 }
649   -
650 580 @article{bates2021distribution,
651   - title={Distribution-free, risk-controlling prediction sets},
652   - author={Bates, Stephen and Angelopoulos, Anastasios and Lei, Lihua and Malik, Jitendra and Jordan, Michael},
653   - journal={Journal of the ACM (JACM)},
654   - volume={68},
655   - number={6},
656   - publisher={ACM New York, NY},
657   - pages={1--34},
658   - year={2021}
  581 + title = {Distribution-free, risk-controlling prediction sets},
  582 + author = {Bates, Stephen and Angelopoulos, Anastasios and Lei, Lihua and Malik, Jitendra and Jordan, Michael},
  583 + year = 2021,
  584 + journal = {Journal of the ACM (JACM)},
  585 + publisher = {ACM New York, NY},
  586 + volume = 68,
  587 + number = 6,
  588 + pages = {1--34}
659 589 }
660   -
661 590 @article{lin2009iterative,
662   - title={Iterative filtering as an alternative algorithm for empirical mode decomposition},
663   - author={Lin, Luan and Wang, Yang and Zhou, Haomin},
664   - journal={Advances in Adaptive Data Analysis},
665   - volume={1},
666   - number={04},
667   - pages={543--560},
668   - year={2009},
669   - publisher={World Scientific}
  591 + title = {Iterative filtering as an alternative algorithm for empirical mode decomposition},
  592 + author = {Lin, Luan and Wang, Yang and Zhou, Haomin},
  593 + year = 2009,
  594 + journal = {Advances in Adaptive Data Analysis},
  595 + publisher = {World Scientific},
  596 + volume = 1,
  597 + number = {04},
  598 + pages = {543--560}
670 599 }
671   -
672 600 @article{cicone2022multivariate,
673   - title={Multivariate fast iterative filtering for the decomposition of nonstationary signals},
674   - author={Cicone, Antonio and Pellegrino, Enza},
675   - journal={IEEE Transactions on Signal Processing},
676   - volume={70},
677   - pages={1521--1531},
678   - year={2022},
679   - publisher={IEEE}
  601 + title = {Multivariate fast iterative filtering for the decomposition of nonstationary signals},
  602 + author = {Cicone, Antonio and Pellegrino, Enza},
  603 + year = 2022,
  604 + journal = {IEEE Transactions on Signal Processing},
  605 + publisher = {IEEE},
  606 + volume = 70,
  607 + pages = {1521--1531}
680 608 }
681   -
682 609 @article{chen2023filter,
683   - title={Filter bank property of direct fast iterative filtering and its applications},
684   - author={Chen, Baojia and Li, Qiurui and Chen, Xueliang and Hai, Zhichao and Zhou, Bin and Chen, Fafa and Xiao, Wenrong and Xiao, Nengqi and Liu, Qiang and Fu, Wenlong and others},
685   - journal={Mechanical Systems and Signal Processing},
686   - volume={204},
687   - pages={110755},
688   - year={2023},
689   - publisher={Elsevier}
  610 + title = {Filter bank property of direct fast iterative filtering and its applications},
  611 + author = {Chen, Baojia and Li, Qiurui and Chen, Xueliang and Hai, Zhichao and Zhou, Bin and Chen, Fafa and Xiao, Wenrong and Xiao, Nengqi and Liu, Qiang and Fu, Wenlong and others},
  612 + year = 2023,
  613 + journal = {Mechanical Systems and Signal Processing},
  614 + publisher = {Elsevier},
  615 + volume = 204,
  616 + pages = 110755
690 617 }
691   -
692 618 @article{cicone2024new,
693   - title={New theoretical insights in the decomposition and time-frequency representation of nonstationary signals: the imfogram algorithm},
694   - author={Cicone, Antonio and Li, Wing Suet and Zhou, Haomin},
695   - journal={Applied and Computational Harmonic Analysis},
696   - volume={71},
697   - pages={101634},
698   - year={2024},
699   - publisher={Elsevier}
  619 + title = {New theoretical insights in the decomposition and time-frequency representation of nonstationary signals: the imfogram algorithm},
  620 + author = {Cicone, Antonio and Li, Wing Suet and Zhou, Haomin},
  621 + year = 2024,
  622 + journal = {Applied and Computational Harmonic Analysis},
  623 + publisher = {Elsevier},
  624 + volume = 71,
  625 + pages = 101634
700 626 }
701   -
702 627 @article{cicone2021numerical,
703   - title={Numerical analysis for iterative filtering with new efficient implementations based on FFT},
704   - author={Cicone, Antonio and Zhou, Haomin},
705   - journal={Numerische Mathematik},
706   - volume={147},
707   - pages={1--28},
708   - year={2021},
709   - publisher={Springer}
  628 + title = {Numerical analysis for iterative filtering with new efficient implementations based on FFT},
  629 + author = {Cicone, Antonio and Zhou, Haomin},
  630 + year = 2021,
  631 + journal = {Numerische Mathematik},
  632 + publisher = {Springer},
  633 + volume = 147,
  634 + pages = {1--28}
710 635 }
711   -
712 636 @article{cicone2020study,
713   - title={Study of boundary conditions in the iterative filtering method for the decomposition of nonstationary signals},
714   - author={Cicone, Antonio and Dell’Acqua, Pietro},
715   - journal={Journal of Computational and Applied Mathematics},
716   - volume={373},
717   - pages={112248},
718   - year={2020},
719   - publisher={Elsevier}
  637 + title = {Study of boundary conditions in the iterative filtering method for the decomposition of nonstationary signals},
  638 + author = {Cicone, Antonio and Dell’Acqua, Pietro},
  639 + year = 2020,
  640 + journal = {Journal of Computational and Applied Mathematics},
  641 + publisher = {Elsevier},
  642 + volume = 373,
  643 + pages = 112248
720 644 }
721   -
722 645 @article{huang1998empirical,
723   - title={The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis},
724   - author={Huang, Norden E and Shen, Zheng and Long, Steven R and Wu, Manli C and Shih, Hsing H and Zheng, Quanan and Yen, Nai-Chyuan and Tung, Chi Chao and Liu, Henry H},
725   - journal={Proceedings of the Royal Society of London. Series A: mathematical, physical and engineering sciences},
726   - volume={454},
727   - number={1971},
728   - pages={903--995},
729   - year={1998},
730   - publisher={The Royal Society}
  646 + title = {The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis},
  647 + author = {Huang, Norden E and Shen, Zheng and Long, Steven R and Wu, Manli C and Shih, Hsing H and Zheng, Quanan and Yen, Nai-Chyuan and Tung, Chi Chao and Liu, Henry H},
  648 + year = 1998,
  649 + journal = {Proceedings of the Royal Society of London. Series A: mathematical, physical and engineering sciences},
  650 + publisher = {The Royal Society},
  651 + volume = 454,
  652 + number = 1971,
  653 + pages = {903--995}
731 654 }
732   -
733 655 @article{de2022survey,
734   - title={A survey on Hilbert-Huang transform: Evolution, challenges and solutions},
735   - author={de Souza, Uender Barbosa and Escola, Jo{\~a}o Paulo Lemos and da Cunha Brito, Leonardo},
736   - journal={Digital Signal Processing},
737   - volume={120},
738   - pages={103292},
739   - year={2022},
740   - publisher={Elsevier}
  656 + title = {A survey on Hilbert-Huang transform: Evolution, challenges and solutions},
  657 + author = {de Souza, Uender Barbosa and Escola, Jo{\~a}o Paulo Lemos and da Cunha Brito, Leonardo},
  658 + year = 2022,
  659 + journal = {Digital Signal Processing},
  660 + publisher = {Elsevier},
  661 + volume = 120,
  662 + pages = 103292
741 663 }
742   -
743 664 @article{garcia2013spectral,
744   - title={Spectral analysis of intracranial pressure signals recorded during infusion studies in patients with hydrocephalus},
745   - author={Garc{\'\i}a, Mar{\'\i}a and Poza, Jes{\'u}s and Santamarta, David and Ab{\'a}solo, Daniel and Barrio, Patricia and Hornero, Roberto},
746   - journal={Medical Engineering \& Physics},
747   - volume={35},
748   - number={10},
749   - pages={1490--1498},
750   - year={2013},
751   - publisher={Elsevier}
  665 + title = {Spectral analysis of intracranial pressure signals recorded during infusion studies in patients with hydrocephalus},
  666 + author = {Garc{\'\i}a, Mar{\'\i}a and Poza, Jes{\'u}s and Santamarta, David and Ab{\'a}solo, Daniel and Barrio, Patricia and Hornero, Roberto},
  667 + year = 2013,
  668 + journal = {Medical Engineering \& Physics},
  669 + publisher = {Elsevier},
  670 + volume = 35,
  671 + number = 10,
  672 + pages = {1490--1498}
752 673 }
753   -
754 674 @article{meel2014between,
755   - title={Between-centre variability in transfer function analysis, a widely used method for linear quantification of the dynamic pressure--flow relation: The CARNet study},
756   - author={Meel-van den Abeelen, Aisha SS and Simpson, David M and Wang, Lotte JY and Slump, Cornelis H and Zhang, Rong and Tarumi, Takashi and Rickards, Caroline A and Payne, Stephen and Mitsis, Georgios D and Kostoglou, Kyriaki and others},
757   - journal={Medical engineering \& physics},
758   - volume={36},
759   - number={5},
760   - pages={620--627},
761   - year={2014},
762   - publisher={Elsevier}
  675 + title = {Between-centre variability in transfer function analysis, a widely used method for linear quantification of the dynamic pressure--flow relation: The CARNet study},
  676 + author = {Meel-van den Abeelen, Aisha SS and Simpson, David M and Wang, Lotte JY and Slump, Cornelis H and Zhang, Rong and Tarumi, Takashi and Rickards, Caroline A and Payne, Stephen and Mitsis, Georgios D and Kostoglou, Kyriaki and others},
  677 + year = 2014,
  678 + journal = {Medical engineering \& physics},
  679 + publisher = {Elsevier},
  680 + volume = 36,
  681 + number = 5,
  682 + pages = {620--627}
763 683 }
764   -
765 684 %%%compliance cérébrale%%%
766 685 @article{kim2009monitoring,
767   - title={The monitoring of relative changes in compartmental compliances of brain},
768   - author={Kim, Dong-Joo and Kasprowicz, Magdalena and Carrera, Emmanuel and Castellani, Gianluca and Zweifel, Christian and Lavinio, Andrea and Smielewski, Peter and Sutcliffe, Michael PF and Pickard, John D and Czosnyka, Marek},
769   - journal={Physiological measurement},
770   - volume={30},
771   - number={7},
772   - pages={647},
773   - year={2009},
774   - publisher={IOP Publishing}
  686 + title = {The monitoring of relative changes in compartmental compliances of brain},
  687 + author = {Kim, Dong-Joo and Kasprowicz, Magdalena and Carrera, Emmanuel and Castellani, Gianluca and Zweifel, Christian and Lavinio, Andrea and Smielewski, Peter and Sutcliffe, Michael PF and Pickard, John D and Czosnyka, Marek},
  688 + year = 2009,
  689 + journal = {Physiological measurement},
  690 + publisher = {IOP Publishing},
  691 + volume = 30,
  692 + number = 7,
  693 + pages = 647
775 694 }
776   -
777 695 @article{marmarou1975compartmental,
778   - title={Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system},
779   - author={Marmarou, Anthony and Shulman, Kenneth and Lamorgese, James},
780   - journal={Journal of neurosurgery},
781   - volume={43},
782   - number={5},
783   - pages={523--534},
784   - year={1975},
785   - publisher={Journal of Neurosurgery Publishing Group}
  696 + title = {Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system},
  697 + author = {Marmarou, Anthony and Shulman, Kenneth and Lamorgese, James},
  698 + year = 1975,
  699 + journal = {Journal of neurosurgery},
  700 + publisher = {Journal of Neurosurgery Publishing Group},
  701 + volume = 43,
  702 + number = 5,
  703 + pages = {523--534}
786 704 }
787   -
788 705 @article{miller1972concepts,
789   - title={Concepts of cerebral perfusion pressure and vascular compression during intracranial hypertension},
790   - author={Miller, J Douglas and Stanek, Albert and Langfitt, Thomas W},
791   - journal={Progress in brain research},
792   - volume={35},
793   - pages={411--432},
794   - year={1972},
795   - publisher={Elsevier}
  706 + title = {Concepts of cerebral perfusion pressure and vascular compression during intracranial hypertension},
  707 + author = {Miller, J Douglas and Stanek, Albert and Langfitt, Thomas W},
  708 + year = 1972,
  709 + journal = {Progress in brain research},
  710 + publisher = {Elsevier},
  711 + volume = 35,
  712 + pages = {411--432}
796 713 }
797   -
798 714 @article{ocamoto2021intracranial,
799   - title={Intracranial compliance concepts and assessment: a scoping review},
800   - author={Ocamoto, Gabriela Nagai and Russo, Thiago Luiz and Mendes Zambetta, Rafaella and Frigieri, Gustavo and Hayashi, Cintya Yukie and Brasil, S{\'e}rgio and Rabelo, Nicollas Nunes and Spavieri Junior, Deusdedit Lineu},
801   - journal={Frontiers in Neurology},
802   - volume={12},
803   - pages={756112},
804   - year={2021},
805   - publisher={Frontiers Media SA}
  715 + title = {Intracranial compliance concepts and assessment: a scoping review},
  716 + author = {Ocamoto, Gabriela Nagai and Russo, Thiago Luiz and Mendes Zambetta, Rafaella and Frigieri, Gustavo and Hayashi, Cintya Yukie and Brasil, S{\'e}rgio and Rabelo, Nicollas Nunes and Spavieri Junior, Deusdedit Lineu},
  717 + year = 2021,
  718 + journal = {Frontiers in Neurology},
  719 + publisher = {Frontiers Media SA},
  720 + volume = 12,
  721 + pages = 756112
806 722 }
807   -
808 723 @book{avezaat1984cerebrospinal,
809   - title={Cerebrospinal fluid pulse pressure and craniospinal dynamics: a theoretical, clinical and experimental study},
810   - author={Avezaat, Cees and van Eijndhoven, Johannes Hubertus Marcellianus},
811   - year={1984}
  724 + title = {Cerebrospinal fluid pulse pressure and craniospinal dynamics: a theoretical, clinical and experimental study},
  725 + author = {Avezaat, Cees and van Eijndhoven, Johannes Hubertus Marcellianus},
  726 + year = 1984
812 727 }
813   -
814 728 @article{gholampour2023intracranial,
815   - title={Intracranial compliance, resistance to CSF-outflow, and pressure-volume index in hydrocephalus patients: A systematic review and meta-analysis},
816   - author={Gholampour, Seifollah and Nguyen, Amber and Chaudry, Saad},
817   - journal={IRBM},
818   - volume={44},
819   - number={5},
820   - pages={100785},
821   - year={2023},
822   - publisher={Elsevier}
  729 + title = {Intracranial compliance, resistance to CSF-outflow, and pressure-volume index in hydrocephalus patients: A systematic review and meta-analysis},
  730 + author = {Gholampour, Seifollah and Nguyen, Amber and Chaudry, Saad},
  731 + year = 2023,
  732 + journal = {IRBM},
  733 + publisher = {Elsevier},
  734 + volume = 44,
  735 + number = 5,
  736 + pages = 100785
823 737 }
824   -
825 738 @article{calviello2018compensatory,
826   - title={Compensatory-reserve-weighted intracranial pressure and its association with outcome after traumatic brain injury},
827   - author={Calviello, L and Donnelly, J and Cardim, D and Robba, C and Zeiler, FA and Smielewski, Peter and Czosnyka, Marek},
828   - journal={Neurocritical care},
829   - volume={28},
830   - pages={212--220},
831   - year={2018},
832   - publisher={Springer}
  739 + title = {Compensatory-reserve-weighted intracranial pressure and its association with outcome after traumatic brain injury},
  740 + author = {Calviello, L and Donnelly, J and Cardim, D and Robba, C and Zeiler, FA and Smielewski, Peter and Czosnyka, Marek},
  741 + year = 2018,
  742 + journal = {Neurocritical care},
  743 + publisher = {Springer},
  744 + volume = 28,
  745 + pages = {212--220}
833 746 }
834   -
835 747 @article{shahsavari2011cerebrovascular,
836   - title={Cerebrovascular mechanical properties and slow waves of intracranial pressure in TBI patients},
837   - author={Shahsavari, Sima and McKelvey, Tomas and Ritzen, Catherine Eriksson and Rydenhag, Bertil},
838   - journal={IEEE transactions on biomedical engineering},
839   - volume={58},
840   - number={7},
841   - pages={2072--2082},
842   - year={2011},
843   - publisher={IEEE}
  748 + title = {Cerebrovascular mechanical properties and slow waves of intracranial pressure in TBI patients},
  749 + author = {Shahsavari, Sima and McKelvey, Tomas and Ritzen, Catherine Eriksson and Rydenhag, Bertil},
  750 + year = 2011,
  751 + journal = {IEEE transactions on biomedical engineering},
  752 + publisher = {IEEE},
  753 + volume = 58,
  754 + number = 7,
  755 + pages = {2072--2082}
844 756 }
845   -
846 757 @article{vallet2021assessment,
847   - title={Assessment of Pressure-Volume Index During Lumbar Infusion Study: What Is the Optimal Method?},
848   - author={Vallet, Alexandra and Gergel{\'e}, Laurent and Jouanneau, Emmanuel and Schmidt, Eric A and Manet, Romain},
849   - journal={Intracranial Pressure and Neuromonitoring XVII},
850   - pages={335--338},
851   - year={2021},
852   - publisher={Springer}
  758 + title = {Assessment of Pressure-Volume Index During Lumbar Infusion Study: What Is the Optimal Method?},
  759 + author = {Vallet, Alexandra and Gergel{\'e}, Laurent and Jouanneau, Emmanuel and Schmidt, Eric A and Manet, Romain},
  760 + year = 2021,
  761 + journal = {Intracranial Pressure and Neuromonitoring XVII},
  762 + publisher = {Springer},
  763 + pages = {335--338}
853 764 }
854   -
855 765 @article{kalisvaart2020update,
856   - title={An update to the Monro--Kellie doctrine to reflect tissue compliance after severe ischemic and hemorrhagic stroke},
857   - author={Kalisvaart, Anna CJ and Wilkinson, Cassandra M and Gu, Sherry and Kung, Tiffany FC and Yager, Jerome and Winship, Ian R and van Landeghem, Frank KH and Colbourne, Frederick},
858   - journal={Scientific reports},
859   - volume={10},
860   - number={1},
861   - pages={22013},
862   - year={2020},
863   - publisher={Nature Publishing Group UK London}
  766 + title = {An update to the Monro--Kellie doctrine to reflect tissue compliance after severe ischemic and hemorrhagic stroke},
  767 + author = {Kalisvaart, Anna CJ and Wilkinson, Cassandra M and Gu, Sherry and Kung, Tiffany FC and Yager, Jerome and Winship, Ian R and van Landeghem, Frank KH and Colbourne, Frederick},
  768 + year = 2020,
  769 + journal = {Scientific reports},
  770 + publisher = {Nature Publishing Group UK London},
  771 + volume = 10,
  772 + number = 1,
  773 + pages = 22013
864 774 }
865   -
866 775 @article{benson2023monro,
867   - title={The Monro-Kellie doctrine: a review and call for revision},
868   - author={Benson, JC and Madhavan, AA and Cutsforth-Gregory, JK and Johnson, DR and Carr, CM},
869   - journal={American Journal of Neuroradiology},
870   - volume={44},
871   - number={1},
872   - pages={2--6},
873   - year={2023},
874   - publisher={Am Soc Neuroradiology}
  776 + title = {The Monro-Kellie doctrine: a review and call for revision},
  777 + author = {Benson, JC and Madhavan, AA and Cutsforth-Gregory, JK and Johnson, DR and Carr, CM},
  778 + year = 2023,
  779 + journal = {American Journal of Neuroradiology},
  780 + publisher = {Am Soc Neuroradiology},
  781 + volume = 44,
  782 + number = 1,
  783 + pages = {2--6}
875 784 }
876   -
877 785 %%% INDICES SPECTRAUX %%%
878 786 @inproceedings{bray1986development,
879   - title={Development of a clinical monitoring system by means of ICP waveform analysis},
880   - author={Bray, RS and Sherwood, AM and Halter, JA and Robertson, Claudia and Grossman, RG},
881   - booktitle={Intracranial Pressure VI: Proceedings of the Sixth International Symposium on Intracranial Pressure Held in Glasgow, Scotland, June 9--13, 1985},
882   - pages={260--264},
883   - year={1986},
884   - organization={Springer}
  787 + title = {Development of a clinical monitoring system by means of ICP waveform analysis},
  788 + author = {Bray, RS and Sherwood, AM and Halter, JA and Robertson, Claudia and Grossman, RG},
  789 + year = 1986,
  790 + booktitle = {Intracranial Pressure VI: Proceedings of the Sixth International Symposium on Intracranial Pressure Held in Glasgow, Scotland, June 9--13, 1985},
  791 + pages = {260--264},
  792 + organization = {Springer}
885 793 }
886   -
887 794 @article{uryga_analysis_2023,
888   - title = {Analysis of intracranial pressure pulse waveform in traumatic brain injury patients: a {CENTER}-{TBI} study},
889   - volume = {139},
890   - copyright = {http://creativecommons.org/licenses/by-nc-nd/4.0/},
891   - issn = {0022-3085, 1933-0693},
892   - shorttitle = {Analysis of intracranial pressure pulse waveform in traumatic brain injury patients},
893   - url = {https://thejns.org/view/journals/j-neurosurg/139/1/article-p201.xml},
894   - doi = {10.3171/2022.10.JNS221523},
895   - language = {en},
896   - number = {1},
897   - urldate = {2024-12-03},
898   - journal = {Journal of Neurosurgery},
899   - author = {Uryga, Agnieszka and Ziółkowski, Arkadiusz and Kazimierska, Agnieszka and Pudełko, Agata and Mataczyński, Cyprian and Lang, Erhard W. and Czosnyka, Marek and Kasprowicz, Magdalena and Anke, Audny and Beer, Ronny and Bellander, Bo-Michael and Beqiri, Erta and Buki, Andras and Cabeleira, Manuel and Carbonara, Marco and Chieregato, Arturo and Citerio, Giuseppe and Clusmann, Hans and Czeiter, Endre and Czosnyka, Marek and Depreitere, Bart and Ercole, Ari and Frisvold, Shirin and Helbok, Raimund and Jankowski, Stefan and Kondziella, Danile and Koskinen, Lars-Owe and Kowark, Ana and Menon, David K. and Meyfroidt, Geert and Moeller, Kirsten and Nelson, David and Piippo-Karjalainen, Anna and Radoi, Andreea and Ragauskas, Arminas and Raj, Rahul and Rhodes, Jonathan and Rocka, Saulius and Rossaint, Rolf and Sahuquillo, Juan and Sakowitz, Oliver and Smielewski, Peter and Stocchetti, Nino and Sundström, Nina and Takala, Riikka and Tamosuitis, Tomas and Tenovuo, Olli and Unterberg, Andreas and Vajkoczy, Peter and Vargiolu, Alessia and Vilcinis, Rimantas and Wolf, Stefan and Younsi, Alexander and Zeiler, Frederick A.},
900   - month = jul,
901   - year = {2023},
902   - pages = {201--211},
903   - file = {Uryga et al. - 2023 - Analysis of intracranial pressure pulse waveform i.pdf:C\:\\Users\\DoL\\Zotero\\storage\\47NCVETS\\Uryga et al. - 2023 - Analysis of intracranial pressure pulse waveform i.pdf:application/pdf},
  795 + title = {Analysis of intracranial pressure pulse waveform in traumatic brain injury patients: a {CENTER}-{TBI} study},
  796 + shorttitle = {Analysis of intracranial pressure pulse waveform in traumatic brain injury patients},
  797 + author = {Uryga, Agnieszka and Ziółkowski, Arkadiusz and Kazimierska, Agnieszka and Pudełko, Agata and Mataczyński, Cyprian and Lang, Erhard W. and Czosnyka, Marek and Kasprowicz, Magdalena and Anke, Audny and Beer, Ronny and Bellander, Bo-Michael and Beqiri, Erta and Buki, Andras and Cabeleira, Manuel and Carbonara, Marco and Chieregato, Arturo and Citerio, Giuseppe and Clusmann, Hans and Czeiter, Endre and Czosnyka, Marek and Depreitere, Bart and Ercole, Ari and Frisvold, Shirin and Helbok, Raimund and Jankowski, Stefan and Kondziella, Danile and Koskinen, Lars-Owe and Kowark, Ana and Menon, David K. and Meyfroidt, Geert and Moeller, Kirsten and Nelson, David and Piippo-Karjalainen, Anna and Radoi, Andreea and Ragauskas, Arminas and Raj, Rahul and Rhodes, Jonathan and Rocka, Saulius and Rossaint, Rolf and Sahuquillo, Juan and Sakowitz, Oliver and Smielewski, Peter and Stocchetti, Nino and Sundström, Nina and Takala, Riikka and Tamosuitis, Tomas and Tenovuo, Olli and Unterberg, Andreas and Vajkoczy, Peter and Vargiolu, Alessia and Vilcinis, Rimantas and Wolf, Stefan and Younsi, Alexander and Zeiler, Frederick A.},
  798 + year = 2023,
  799 + month = jul,
  800 + journal = {Journal of Neurosurgery},
  801 + volume = 139,
  802 + number = 1,
  803 + pages = {201--211},
  804 + doi = {10.3171/2022.10.JNS221523},
  805 + issn = {0022-3085, 1933-0693},
  806 + url = {https://thejns.org/view/journals/j-neurosurg/139/1/article-p201.xml},
  807 + urldate = {2024-12-03},
  808 + copyright = {http://creativecommons.org/licenses/by-nc-nd/4.0/},
  809 + language = {en},
  810 + file = {Uryga et al. - 2023 - Analysis of intracranial pressure pulse waveform i.pdf:C\:\\Users\\DoL\\Zotero\\storage\\47NCVETS\\Uryga et al. - 2023 - Analysis of intracranial pressure pulse waveform i.pdf:application/pdf}
904 811 }
905   -
906 812 @article{robertson_clinical_1989,
907   - title = {Clinical experience with a continuous monitor of intracranial compliance},
908   - volume = {71},
909   - issn = {0022-3085},
910   - url = {https://thejns.org/view/journals/j-neurosurg/71/5/article-p673.xml},
911   - doi = {10.3171/jns.1989.71.5.0673},
912   - language = {en},
913   - number = {5},
914   - urldate = {2024-12-03},
915   - journal = {Journal of Neurosurgery},
916   - author = {Robertson, Claudia S. and Narayan, Raj K. and Contant, Charles F. and Grossman, Robert G. and Gokaslan, Ziya L. and Pahwa, Rajesh and Caram, Pedro and Bray, Robert S. and Sherwood, Arthur M.},
917   - month = nov,
918   - year = {1989},
919   - pages = {673--680},
920   - file = {Robertson et al. - 1989 - Clinical experience with a continuous monitor of i.pdf:C\:\\Users\\DoL\\Zotero\\storage\\6AZAKGYK\\Robertson et al. - 1989 - Clinical experience with a continuous monitor of i.pdf:application/pdf},
  813 + title = {Clinical experience with a continuous monitor of intracranial compliance},
  814 + author = {Robertson, Claudia S. and Narayan, Raj K. and Contant, Charles F. and Grossman, Robert G. and Gokaslan, Ziya L. and Pahwa, Rajesh and Caram, Pedro and Bray, Robert S. and Sherwood, Arthur M.},
  815 + year = 1989,
  816 + month = nov,
  817 + journal = {Journal of Neurosurgery},
  818 + volume = 71,
  819 + number = 5,
  820 + pages = {673--680},
  821 + doi = {10.3171/jns.1989.71.5.0673},
  822 + issn = {0022-3085},
  823 + url = {https://thejns.org/view/journals/j-neurosurg/71/5/article-p673.xml},
  824 + urldate = {2024-12-03},
  825 + language = {en},
  826 + file = {Robertson et al. - 1989 - Clinical experience with a continuous monitor of i.pdf:C\:\\Users\\DoL\\Zotero\\storage\\6AZAKGYK\\Robertson et al. - 1989 - Clinical experience with a continuous monitor of i.pdf:application/pdf}
921 827 }
922   -
923 828 @article{contant_intracranial_1995,
924   - title = {Intracranial pressure waveform indices in transient and refractory intracranial hypertension},
925   - language = {en},
926   - year = {1995},
927   - journal = {Journal of Neuroscience methods},
928   - author = {Contant, Charles F and Robertson, Claudia S and Crouch, Jeffery and Gopinath, Shankar P and Narayan, Raj K and Grossman, Robert G},
929   - file = {Contant et al. - Intracranial pressure waveform indices in transien.pdf:C\:\\Users\\DoL\\Zotero\\storage\\RQIALFSH\\Contant et al. - Intracranial pressure waveform indices in transien.pdf:application/pdf},
  829 + title = {Intracranial pressure waveform indices in transient and refractory intracranial hypertension},
  830 + author = {Contant, Charles F and Robertson, Claudia S and Crouch, Jeffery and Gopinath, Shankar P and Narayan, Raj K and Grossman, Robert G},
  831 + year = 1995,
  832 + journal = {Journal of Neuroscience methods},
  833 + language = {en},
  834 + file = {Contant et al. - Intracranial pressure waveform indices in transien.pdf:C\:\\Users\\DoL\\Zotero\\storage\\RQIALFSH\\Contant et al. - Intracranial pressure waveform indices in transien.pdf:application/pdf}
930 835 }
931   -
932 836 @article{takizawa_changes_nodate,
933   - title = {Changes in the cerebrospinal fluid pulse wave spectrum associated with raised intracranial pressure},
934   - volume = {20},
935   - number = {3},
936   - journal = {Neurosurgery},
937   - year = {1987},
938   - author = {Takizawa, Hideo and Gabra-Sanders, Thea and Miller, Douglas J.},
939   - pages = {355--361},
940   - file = {_.pdf:C\:\\Users\\DoL\\Zotero\\storage\\JACQKDZI\\_.pdf:application/pdf},
  837 + title = {Changes in the cerebrospinal fluid pulse wave spectrum associated with raised intracranial pressure},
  838 + author = {Takizawa, Hideo and Gabra-Sanders, Thea and Miller, Douglas J.},
  839 + year = 1987,
  840 + journal = {Neurosurgery},
  841 + volume = 20,
  842 + number = 3,
  843 + pages = {355--361},
  844 + file = {_.pdf:C\:\\Users\\DoL\\Zotero\\storage\\JACQKDZI\\_.pdf:application/pdf}
941 845 }
942   -
943   -
944 846 @article{zakrzewska_intracranial_2021,
945   - title = {Intracranial pulse pressure waveform analysis using the higher harmonics centroid},
946   - volume = {163},
947   - issn = {0001-6268, 0942-0940},
948   - url = {https://link.springer.com/10.1007/s00701-021-04958-1},
949   - doi = {10.1007/s00701-021-04958-1},
950   - language = {en},
951   - number = {12},
952   - urldate = {2024-12-12},
953   - journal = {Acta Neurochirurgica},
954   - author = {Zakrzewska, Agnieszka P. and Placek, Michał M. and Czosnyka, Marek and Kasprowicz, Magdalena and Lang, Erhard W.},
955   - month = dec,
956   - year = {2021},
957   - pages = {3249--3258},
958   - file = {Zakrzewska et al. - 2021 - Intracranial pulse pressure waveform analysis usin.pdf:C\:\\Users\\DoL\\Zotero\\storage\\FBDCSBL9\\Zakrzewska et al. - 2021 - Intracranial pulse pressure waveform analysis usin.pdf:application/pdf},
  847 + title = {Intracranial pulse pressure waveform analysis using the higher harmonics centroid},
  848 + author = {Zakrzewska, Agnieszka P. and Placek, Michał M. and Czosnyka, Marek and Kasprowicz, Magdalena and Lang, Erhard W.},
  849 + year = 2021,
  850 + month = dec,
  851 + journal = {Acta Neurochirurgica},
  852 + volume = 163,
  853 + number = 12,
  854 + pages = {3249--3258},
  855 + doi = {10.1007/s00701-021-04958-1},
  856 + issn = {0001-6268, 0942-0940},
  857 + url = {https://link.springer.com/10.1007/s00701-021-04958-1},
  858 + urldate = {2024-12-12},
  859 + language = {en},
  860 + file = {Zakrzewska et al. - 2021 - Intracranial pulse pressure waveform analysis usin.pdf:C\:\\Users\\DoL\\Zotero\\storage\\FBDCSBL9\\Zakrzewska et al. - 2021 - Intracranial pulse pressure waveform analysis usin.pdf:application/pdf}
959 861 }
960   -
961 862 %%% AMPLITUDE %%%
962   -
963 863 @article{szewczykowski1977fast,
964   - title={A fast method of estimating the elastance of the intracranial system: a practical application in neurosurgery},
965   - author={Szewczykowski, Jerzy and Kunicki, Adam and Dytko, Pawel and Korsak-liwka, Jolanta and others},
966   - journal={Journal of neurosurgery},
967   - volume={47},
968   - number={1},
969   - pages={19--26},
970   - year={1977},
971   - publisher={Journal of Neurosurgery Publishing Group}
  864 + title = {A fast method of estimating the elastance of the intracranial system: a practical application in neurosurgery},
  865 + author = {Szewczykowski, Jerzy and Kunicki, Adam and Dytko, Pawel and Korsak-liwka, Jolanta and others},
  866 + year = 1977,
  867 + journal = {Journal of neurosurgery},
  868 + publisher = {Journal of Neurosurgery Publishing Group},
  869 + volume = 47,
  870 + number = 1,
  871 + pages = {19--26}
972 872 }
973   -
974 873 @article{holm2008frequency,
975   - title={The frequency domain versus time domain methods for processing of intracranial pressure (ICP) signals},
976   - author={Holm, Sverre and Eide, Per Kristian},
977   - journal={Medical engineering \& physics},
978   - volume={30},
979   - number={2},
980   - pages={164--170},
981   - year={2008},
982   - publisher={Elsevier}
  874 + title = {The frequency domain versus time domain methods for processing of intracranial pressure (ICP) signals},
  875 + author = {Holm, Sverre and Eide, Per Kristian},
  876 + year = 2008,
  877 + journal = {Medical engineering \& physics},
  878 + publisher = {Elsevier},
  879 + volume = 30,
  880 + number = 2,
  881 + pages = {164--170}
983 882 }
984   -
985 883 @inproceedings{bishop2018multi,
986   - title={Multi-scale peak and trough detection optimised for periodic and quasi-periodic neuroscience data},
987   - author={Bishop, Steven M and Ercole, Ari},
988   - booktitle={Intracranial Pressure \& Neuromonitoring XVI},
989   - pages={189--195},
990   - year={2018},
991   - organization={Springer}
  884 + title = {Multi-scale peak and trough detection optimised for periodic and quasi-periodic neuroscience data},
  885 + author = {Bishop, Steven M and Ercole, Ari},
  886 + year = 2018,
  887 + booktitle = {Intracranial Pressure \& Neuromonitoring XVI},
  888 + pages = {189--195},
  889 + organization = {Springer}
992 890 }
993   -
994 891 @inproceedings{czosnyka1988system,
995   - title={A System for Intracranial Pressure Processing and Interpretation in Intensive Care},
996   - author={Czosnyka, M and Zaworski, W and Wollk-Laniewski, P and Batorski, L},
997   - booktitle={Advances in Biomedical Measurement},
998   - pages={101--110},
999   - year={1988},
1000   - organization={Springer}
  892 + title = {A System for Intracranial Pressure Processing and Interpretation in Intensive Care},
  893 + author = {Czosnyka, M and Zaworski, W and Wollk-Laniewski, P and Batorski, L},
  894 + year = 1988,
  895 + booktitle = {Advances in Biomedical Measurement},
  896 + pages = {101--110},
  897 + organization = {Springer}
1001 898 }
1002   -
1003 899 @article{eide2016correlation,
1004   - title={The correlation between pulsatile intracranial pressure and indices of intracranial pressure-volume reserve capacity: results from ventricular infusion testing},
1005   - author={Eide, Per Kristian},
1006   - journal={Journal of neurosurgery},
1007   - volume={125},
1008   - number={6},
1009   - pages={1493--1503},
1010   - year={2016},
1011   - publisher={American Association of Neurological Surgeons}
  900 + title = {The correlation between pulsatile intracranial pressure and indices of intracranial pressure-volume reserve capacity: results from ventricular infusion testing},
  901 + author = {Eide, Per Kristian},
  902 + year = 2016,
  903 + journal = {Journal of neurosurgery},
  904 + publisher = {American Association of Neurological Surgeons},
  905 + volume = 125,
  906 + number = 6,
  907 + pages = {1493--1503}
1012 908 }
1013   -
1014 909 @article{zhu2023spindle,
1015   - title={Spindle wave in intracranial pressure signal analysis for patients with traumatic brain injury: A single-center prospective observational cohort study},
1016   - author={Zhu, Jun and Shan, Yingchi and Li, Yihua and Liu, Jiaqi and Wu, Xiang and Gao, Guoyi},
1017   - journal={Frontiers in Physiology},
1018   - volume={13},
1019   - pages={1043328},
1020   - year={2023},
1021   - publisher={Frontiers Media SA}
  910 + title = {Spindle wave in intracranial pressure signal analysis for patients with traumatic brain injury: A single-center prospective observational cohort study},
  911 + author = {Zhu, Jun and Shan, Yingchi and Li, Yihua and Liu, Jiaqi and Wu, Xiang and Gao, Guoyi},
  912 + year = 2023,
  913 + journal = {Frontiers in Physiology},
  914 + publisher = {Frontiers Media SA},
  915 + volume = 13,
  916 + pages = 1043328
1022 917 }
1023   -
1024 918 @article{czosnyka2004monitoring,
1025   - title={Monitoring and interpretation of intracranial pressure},
1026   - author={Czosnyka, Marek and Pickard, John D},
1027   - journal={Journal of Neurology, Neurosurgery \& Psychiatry},
1028   - volume={75},
1029   - number={6},
1030   - pages={813--821},
1031   - year={2004},
1032   - publisher={BMJ Publishing Group Ltd}
  919 + title = {Monitoring and interpretation of intracranial pressure},
  920 + author = {Czosnyka, Marek and Pickard, John D},
  921 + year = 2004,
  922 + journal = {Journal of Neurology, Neurosurgery \& Psychiatry},
  923 + publisher = {BMJ Publishing Group Ltd},
  924 + volume = 75,
  925 + number = 6,
  926 + pages = {813--821}
1033 927 }
1034   -
1035 928 @article{donnelly2020observations,
1036   - title={Observations on the cerebral effects of refractory intracranial hypertension after severe traumatic brain injury},
1037   - author={Donnelly, Joseph and Smielewski, Peter and Adams, Hadie and Zeiler, Frederick A and Cardim, Danilo and Liu, Xiuyun and Fedriga, Marta and Hutchinson, Peter and Menon, David K and Czosnyka, Marek},
1038   - journal={Neurocritical care},
1039   - volume={32},
1040   - pages={437--447},
1041   - year={2020},
1042   - publisher={Springer}
  929 + title = {Observations on the cerebral effects of refractory intracranial hypertension after severe traumatic brain injury},
  930 + author = {Donnelly, Joseph and Smielewski, Peter and Adams, Hadie and Zeiler, Frederick A and Cardim, Danilo and Liu, Xiuyun and Fedriga, Marta and Hutchinson, Peter and Menon, David K and Czosnyka, Marek},
  931 + year = 2020,
  932 + journal = {Neurocritical care},
  933 + publisher = {Springer},
  934 + volume = 32,
  935 + pages = {437--447}
1043 936 }
1044   -
1045 937 @inproceedings{pineda2018assessing,
1046   - title={Assessing cerebral hemodynamic stability after brain injury},
1047   - author={Pineda, Bianca and Kosinski, Colin and Kim, Nam and Danish, Shabbar and Craelius, William},
1048   - booktitle={Intracranial Pressure \& Neuromonitoring XVI},
1049   - pages={297--301},
1050   - year={2018},
1051   - organization={Springer}
  938 + title = {Assessing cerebral hemodynamic stability after brain injury},
  939 + author = {Pineda, Bianca and Kosinski, Colin and Kim, Nam and Danish, Shabbar and Craelius, William},
  940 + year = 2018,
  941 + booktitle = {Intracranial Pressure \& Neuromonitoring XVI},
  942 + pages = {297--301},
  943 + organization = {Springer}
1052 944 }
1053   -
1054 945 @article{islam2024continuous,
1055   - title={Continuous monitoring methods of cerebral compliance and compensatory reserve: a scoping review of human literature},
1056   - author={Islam, Abrar and Froese, Logan and Bergmann, Tobias and Gomez, Alwyn and Sainbhi, Amanjyot Singh and Vakitbilir, Nuray and Stein, Kevin Y and Marquez, Izabella and Ibrahim, Younis and Zeiler, Frederick A},
1057   - journal={Physiological Measurement},
1058   - year={2024}
  946 + title = {Continuous monitoring methods of cerebral compliance and compensatory reserve: a scoping review of human literature},
  947 + author = {Islam, Abrar and Froese, Logan and Bergmann, Tobias and Gomez, Alwyn and Sainbhi, Amanjyot Singh and Vakitbilir, Nuray and Stein, Kevin Y and Marquez, Izabella and Ibrahim, Younis and Zeiler, Frederick A},
  948 + year = 2024,
  949 + journal = {Physiological Measurement}
1059 950 }
1060   -
1061 951 @article{zeiler2018impaired,
1062   - title={Impaired cerebral compensatory reserve is associated with admission imaging characteristics of diffuse insult in traumatic brain injury},
1063   - author={Zeiler, Frederick A and Kim, Dong-Joo and Cabeleira, Manuel and Calviello, Leanne and Smielewski, Peter and Czosnyka, Marek},
1064   - journal={Acta neurochirurgica},
1065   - volume={160},
1066   - pages={2277--2287},
1067   - year={2018},
1068   - publisher={Springer}
  952 + title = {Impaired cerebral compensatory reserve is associated with admission imaging characteristics of diffuse insult in traumatic brain injury},
  953 + author = {Zeiler, Frederick A and Kim, Dong-Joo and Cabeleira, Manuel and Calviello, Leanne and Smielewski, Peter and Czosnyka, Marek},
  954 + year = 2018,
  955 + journal = {Acta neurochirurgica},
  956 + publisher = {Springer},
  957 + volume = 160,
  958 + pages = {2277--2287}
1069 959 }
1070   -
1071 960 @inproceedings{czosnyka2005concept,
1072   - title={Concept of “true ICP” in monitoring and prognostication in head trauma},
1073   - author={Czosnyka, M and Steiner, L and Balestreri, M and Schmidt, E and Smielewski, P and Hutchinson, PJ and Pickard, JD},
1074   - booktitle={Intracranial Pressure and Brain Monitoring XII},
1075   - pages={341--344},
1076   - year={2005},
1077   - organization={Springer}
  961 + title = {Concept of “true ICP” in monitoring and prognostication in head trauma},
  962 + author = {Czosnyka, M and Steiner, L and Balestreri, M and Schmidt, E and Smielewski, P and Hutchinson, PJ and Pickard, JD},
  963 + year = 2005,
  964 + booktitle = {Intracranial Pressure and Brain Monitoring XII},
  965 + pages = {341--344},
  966 + organization = {Springer}
1078 967 }
1079   -
1080 968 @inproceedings{czosnyka2012modeling,
1081   - title={Modeling of CSF dynamics: legacy of Professor Anthony Marmarou},
1082   - author={Czosnyka, Marek and Czosnyka, Zofia and Agarwal-Harding, Kiran J and Pickard, John D},
1083   - booktitle={Hydrocephalus: Selected Papers from the International Workshop in Crete, 2010},
1084   - pages={9--14},
1085   - year={2012},
1086   - organization={Springer}
  969 + title = {Modeling of CSF dynamics: legacy of Professor Anthony Marmarou},
  970 + author = {Czosnyka, Marek and Czosnyka, Zofia and Agarwal-Harding, Kiran J and Pickard, John D},
  971 + year = 2012,
  972 + booktitle = {Hydrocephalus: Selected Papers from the International Workshop in Crete, 2010},
  973 + pages = {9--14},
  974 + organization = {Springer}
1087 975 }
1088   -
1089 976 @article{wagshul2011pulsating,
1090   - title={The pulsating brain: a review of experimental and clinical studies of intracranial pulsatility},
1091   - author={Wagshul, Mark E and Eide, Per K and Madsen, Joseph R},
1092   - journal={Fluids and Barriers of the CNS},
1093   - volume={8},
1094   - pages={1--23},
1095   - year={2011},
1096   - publisher={Springer}
  977 + title = {The pulsating brain: a review of experimental and clinical studies of intracranial pulsatility},
  978 + author = {Wagshul, Mark E and Eide, Per K and Madsen, Joseph R},
  979 + year = 2011,
  980 + journal = {Fluids and Barriers of the CNS},
  981 + publisher = {Springer},
  982 + volume = 8,
  983 + pages = {1--23}
1097 984 }
1098   -
1099 985 @article{eide2011randomized,
1100   - title={A randomized and blinded single-center trial comparing the effect of intracranial pressure and intracranial pressure wave amplitude-guided intensive care management on early clinical state and 12-month outcome in patients with aneurysmal subarachnoid hemorrhage},
1101   - author={Eide, Per Kristian and Bentsen, Gunnar and Sorteberg, Angelika G and Marthinsen, P{\aa}l Bache and Stubhaug, Audun and Sorteberg, Wilhelm},
1102   - journal={Neurosurgery},
1103   - volume={69},
1104   - number={5},
1105   - pages={1105--1115},
1106   - year={2011},
1107   - publisher={LWW}
  986 + title = {A randomized and blinded single-center trial comparing the effect of intracranial pressure and intracranial pressure wave amplitude-guided intensive care management on early clinical state and 12-month outcome in patients with aneurysmal subarachnoid hemorrhage},
  987 + author = {Eide, Per Kristian and Bentsen, Gunnar and Sorteberg, Angelika G and Marthinsen, P{\aa}l Bache and Stubhaug, Audun and Sorteberg, Wilhelm},
  988 + year = 2011,
  989 + journal = {Neurosurgery},
  990 + publisher = {LWW},
  991 + volume = 69,
  992 + number = 5,
  993 + pages = {1105--1115}
1108 994 }
1109   -
1110 995 @article{eide2013intracranial,
1111   - title={An intracranial pressure-derived index monitored simultaneously from two separate sensors in patients with cerebral bleeds: comparison of findings},
1112   - author={Eide, Per Kristian and Sorteberg, Wilhelm},
1113   - journal={BioMedical Engineering OnLine},
1114   - volume={12},
1115   - pages={1--13},
1116   - year={2013},
1117   - publisher={Springer}
  996 + title = {An intracranial pressure-derived index monitored simultaneously from two separate sensors in patients with cerebral bleeds: comparison of findings},
  997 + author = {Eide, Per Kristian and Sorteberg, Wilhelm},
  998 + year = 2013,
  999 + journal = {BioMedical Engineering OnLine},
  1000 + publisher = {Springer},
  1001 + volume = 12,
  1002 + pages = {1--13}
1118 1003 }
1119   -
1120 1004 @article{spiegelberg2020raq,
1121   - title={RAQ: a novel surrogate for the craniospinal pressure--volume relationship},
1122   - author={Spiegelberg, Andreas and Krause, Matthias and Meixensberger, Juergen and Kurtcuoglu, Vartan},
1123   - journal={Physiological measurement},
1124   - volume={41},
1125   - number={9},
1126   - pages={094002},
1127   - year={2020},
1128   - publisher={IOP Publishing}
  1005 + title = {RAQ: a novel surrogate for the craniospinal pressure--volume relationship},
  1006 + author = {Spiegelberg, Andreas and Krause, Matthias and Meixensberger, Juergen and Kurtcuoglu, Vartan},
  1007 + year = 2020,
  1008 + journal = {Physiological measurement},
  1009 + publisher = {IOP Publishing},
  1010 + volume = 41,
  1011 + number = 9,
  1012 + pages = {094002}
1129 1013 }
1130   -
1131 1014 @article{kalaiarasan2024novel,
1132   - title={A Novel Methodology for Intracranial Pressure Subpeak Identification Enabling Morphological Feature Analysis},
1133   - author={Kalaiarasan, Varun Vinayak and Miller, Marcella and Han, Xu and Foreman, Brandon and Jia, Xiaodong},
1134   - journal={IEEE Transactions on Biomedical Engineering},
1135   - year={2024},
1136   - publisher={IEEE}
  1015 + title = {A Novel Methodology for Intracranial Pressure Subpeak Identification Enabling Morphological Feature Analysis},
  1016 + author = {Kalaiarasan, Varun Vinayak and Miller, Marcella and Han, Xu and Foreman, Brandon and Jia, Xiaodong},
  1017 + year = 2024,
  1018 + journal = {IEEE Transactions on Biomedical Engineering},
  1019 + publisher = {IEEE}
1137 1020 }
1138   -
1139 1021 %%% P2/P1%%%
1140 1022 @article{lee2015morphological,
1141   - title={Morphological feature extraction from a continuous intracranial pressure pulse via a peak clustering algorithm},
1142   - author={Lee, Hack-Jin and Jeong, Eun-Jin and Kim, Hakseung and Czosnyka, Marek and Kim, Dong-Joo},
1143   - journal={IEEE Transactions on Biomedical Engineering},
1144   - volume={63},
1145   - number={10},
1146   - pages={2169--2176},
1147   - year={2015},
1148   - publisher={IEEE}
  1023 + title = {Morphological feature extraction from a continuous intracranial pressure pulse via a peak clustering algorithm},
  1024 + author = {Lee, Hack-Jin and Jeong, Eun-Jin and Kim, Hakseung and Czosnyka, Marek and Kim, Dong-Joo},
  1025 + year = 2015,
  1026 + journal = {IEEE Transactions on Biomedical Engineering},
  1027 + publisher = {IEEE},
  1028 + volume = 63,
  1029 + number = 10,
  1030 + pages = {2169--2176}
1149 1031 }
1150   -
1151 1032 @article{hu2008morphological,
1152   - title={Morphological clustering and analysis of continuous intracranial pressure},
1153   - author={Hu, Xiao and Xu, Peng and Scalzo, Fabien and Vespa, Paul and Bergsneider, Marvin},
1154   - journal={IEEE Transactions on Biomedical Engineering},
1155   - volume={56},
1156   - number={3},
1157   - pages={696--705},
1158   - year={2008},
1159   - publisher={IEEE}
  1033 + title = {Morphological clustering and analysis of continuous intracranial pressure},
  1034 + author = {Hu, Xiao and Xu, Peng and Scalzo, Fabien and Vespa, Paul and Bergsneider, Marvin},
  1035 + year = 2008,
  1036 + journal = {IEEE Transactions on Biomedical Engineering},
  1037 + publisher = {IEEE},
  1038 + volume = 56,
  1039 + number = 3,
  1040 + pages = {696--705}
1160 1041 }
1161   -
1162 1042 @article{hu2010intracranial,
1163   - title={Intracranial pressure pulse morphological features improved detection of decreased cerebral blood flow},
1164   - author={Hu, Xiao and Glenn, Thomas and Scalzo, Fabien and Bergsneider, Marvin and Sarkiss, Chris and Martin, Neil and Vespa, Paul},
1165   - journal={Physiological measurement},
1166   - volume={31},
1167   - number={5},
1168   - pages={679},
1169   - year={2010},
1170   - publisher={IOP Publishing}
  1043 + title = {Intracranial pressure pulse morphological features improved detection of decreased cerebral blood flow},
  1044 + author = {Hu, Xiao and Glenn, Thomas and Scalzo, Fabien and Bergsneider, Marvin and Sarkiss, Chris and Martin, Neil and Vespa, Paul},
  1045 + year = 2010,
  1046 + journal = {Physiological measurement},
  1047 + publisher = {IOP Publishing},
  1048 + volume = 31,
  1049 + number = 5,
  1050 + pages = 679
1171 1051 }
1172   -
1173 1052 @article{scalzo2012bayesian,
1174   - title={Bayesian tracking of intracranial pressure signal morphology},
1175   - author={Scalzo, Fabien and Asgari, Shadnaz and Kim, Sunghan and Bergsneider, Marvin and Hu, Xiao},
1176   - journal={Artificial intelligence in medicine},
1177   - volume={54},
1178   - number={2},
1179   - pages={115--123},
1180   - year={2012},
1181   - publisher={Elsevier}
  1053 + title = {Bayesian tracking of intracranial pressure signal morphology},
  1054 + author = {Scalzo, Fabien and Asgari, Shadnaz and Kim, Sunghan and Bergsneider, Marvin and Hu, Xiao},
  1055 + year = 2012,
  1056 + journal = {Artificial intelligence in medicine},
  1057 + publisher = {Elsevier},
  1058 + volume = 54,
  1059 + number = 2,
  1060 + pages = {115--123}
1182 1061 }
1183   -
1184 1062 @article{rashidinejad2020patient,
1185   - title={Patient-adaptable intracranial pressure morphology analysis using a probabilistic model-based approach},
1186   - author={Rashidinejad, Paria and Hu, Xiao and Russell, Stuart},
1187   - journal={Physiological measurement},
1188   - volume={41},
1189   - number={10},
1190   - pages={104003},
1191   - year={2020},
1192   - publisher={IOP Publishing}
  1063 + title = {Patient-adaptable intracranial pressure morphology analysis using a probabilistic model-based approach},
  1064 + author = {Rashidinejad, Paria and Hu, Xiao and Russell, Stuart},
  1065 + year = 2020,
  1066 + journal = {Physiological measurement},
  1067 + publisher = {IOP Publishing},
  1068 + volume = 41,
  1069 + number = 10,
  1070 + pages = 104003
1193 1071 }
1194   -
1195 1072 @article{mataczynski2021end,
1196   - title={End-to-end automatic morphological classification of intracranial pressure pulse waveforms using deep learning},
1197   - author={Mataczy{\'n}ski, Cyprian and Kazimierska, Agnieszka and Uryga, Agnieszka and Burzy{\'n}ska, Ma{\l}gorzata and Rusiecki, Andrzej and Kasprowicz, Magdalena},
1198   - journal={IEEE Journal of Biomedical and Health Informatics},
1199   - volume={26},
1200   - number={2},
1201   - pages={494--504},
1202   - year={2021},
1203   - publisher={IEEE}
  1073 + title = {End-to-end automatic morphological classification of intracranial pressure pulse waveforms using deep learning},
  1074 + author = {Mataczy{\'n}ski, Cyprian and Kazimierska, Agnieszka and Uryga, Agnieszka and Burzy{\'n}ska, Ma{\l}gorzata and Rusiecki, Andrzej and Kasprowicz, Magdalena},
  1075 + year = 2021,
  1076 + journal = {IEEE Journal of Biomedical and Health Informatics},
  1077 + publisher = {IEEE},
  1078 + volume = 26,
  1079 + number = 2,
  1080 + pages = {494--504}
1204 1081 }
1205   -
1206 1082 @article{nucci2016intracranial,
1207   - title={Intracranial pressure wave morphological classification: automated analysis and clinical validation},
1208   - author={Nucci, Carlotta Ginevra and De Bonis, Pasquale and Mangiola, Annunziato and Santini, Pietro and Sciandrone, Marco and Risi, Arnaldo and Anile, Carmelo},
1209   - journal={Acta neurochirurgica},
1210   - volume={158},
1211   - pages={581--588},
1212   - year={2016},
1213   - publisher={Springer}
  1083 + title = {Intracranial pressure wave morphological classification: automated analysis and clinical validation},
  1084 + author = {Nucci, Carlotta Ginevra and De Bonis, Pasquale and Mangiola, Annunziato and Santini, Pietro and Sciandrone, Marco and Risi, Arnaldo and Anile, Carmelo},
  1085 + year = 2016,
  1086 + journal = {Acta neurochirurgica},
  1087 + publisher = {Springer},
  1088 + volume = 158,
  1089 + pages = {581--588}
1214 1090 }
1215   -
1216 1091 @article{kazimierska2023relationship,
1217   - title={Relationship between the shape of intracranial pressure pulse waveform and computed tomography characteristics in patients after traumatic brain injury},
1218   - author={Kazimierska, Agnieszka and Uryga, Agnieszka and Mataczy{\'n}ski, Cyprian and Czosnyka, Marek and Lang, Erhard W and Kasprowicz, Magdalena},
1219   - journal={Critical Care},
1220   - volume={27},
1221   - number={1},
1222   - pages={447},
1223   - year={2023},
1224   - publisher={Springer}
  1092 + title = {Relationship between the shape of intracranial pressure pulse waveform and computed tomography characteristics in patients after traumatic brain injury},
  1093 + author = {Kazimierska, Agnieszka and Uryga, Agnieszka and Mataczy{\'n}ski, Cyprian and Czosnyka, Marek and Lang, Erhard W and Kasprowicz, Magdalena},
  1094 + year = 2023,
  1095 + journal = {Critical Care},
  1096 + publisher = {Springer},
  1097 + volume = 27,
  1098 + number = 1,
  1099 + pages = 447
1225 1100 }
1226   -
1227 1101 %%% PIC et Doppler %%%
1228   -
1229 1102 @article{ract2007transcranial,
1230   - title={Transcranial Doppler ultrasound goal-directed therapy for the early management of severe traumatic brain injury},
1231   - author={Ract, Catherine and Le Moigno, Sophie and Bruder, Nicolas and Vigu{\'e}, Bernard},
1232   - journal={Intensive care medicine},
1233   - volume={33},
1234   - pages={645--651},
1235   - year={2007},
1236   - publisher={Springer}
  1103 + title = {Transcranial Doppler ultrasound goal-directed therapy for the early management of severe traumatic brain injury},
  1104 + author = {Ract, Catherine and Le Moigno, Sophie and Bruder, Nicolas and Vigu{\'e}, Bernard},
  1105 + year = 2007,
  1106 + journal = {Intensive care medicine},
  1107 + publisher = {Springer},
  1108 + volume = 33,
  1109 + pages = {645--651}
1237 1110 }
1238   -
1239 1111 @article{baska2024transcranial,
1240   - title={Transcranial sonography: practical use in the intensive care unit},
1241   - author={Baska, Aleksandra and Sporysz-Janiec, Krystian and Figura, Monika and Andruszkiewicz, Pawe{\l} and Zawadka, Mateusz},
1242   - journal={Anaesthesiology Intensive Therapy},
1243   - volume={56},
1244   - number={5},
1245   - pages={267--276},
1246   - year={2024},
1247   - publisher={Termedia}
  1112 + title = {Transcranial sonography: practical use in the intensive care unit},
  1113 + author = {Baska, Aleksandra and Sporysz-Janiec, Krystian and Figura, Monika and Andruszkiewicz, Pawe{\l} and Zawadka, Mateusz},
  1114 + year = 2024,
  1115 + journal = {Anaesthesiology Intensive Therapy},
  1116 + publisher = {Termedia},
  1117 + volume = 56,
  1118 + number = 5,
  1119 + pages = {267--276}
1248 1120 }
1249   -
1250 1121 @article{martinez2024non,
1251   - title={Non-invasive methods for intracranial pressure monitoring in traumatic brain injury using transcranial doppler: a scoping review},
1252   - author={Mart{\'\i}nez-Palacios, Karol and V{\'a}squez-Garc{\'\i}a, Sebasti{\'a}n and Fariyike, Olubunmi A and Robba, Chiara and Rubiano, Andr{\'e}s M},
1253   - journal={Journal of neurotrauma},
1254   - volume={41},
1255   - number={11-12},
1256   - pages={1282--1298},
1257   - year={2024},
1258   - publisher={Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…}
  1122 + title = {Non-invasive methods for intracranial pressure monitoring in traumatic brain injury using transcranial doppler: a scoping review},
  1123 + author = {Mart{\'\i}nez-Palacios, Karol and V{\'a}squez-Garc{\'\i}a, Sebasti{\'a}n and Fariyike, Olubunmi A and Robba, Chiara and Rubiano, Andr{\'e}s M},
  1124 + year = 2024,
  1125 + journal = {Journal of neurotrauma},
  1126 + publisher = {Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…},
  1127 + volume = 41,
  1128 + number = {11-12},
  1129 + pages = {1282--1298}
1259 1130 }
1260   -
1261 1131 @article{dokponou2023transcranial,
1262   - title={Transcranial doppler in the non-invasive estimation of intracranial pressure in traumatic brain injury compared to other non-invasive methods in lower-middle income countries: Systematic review and meta-analysis},
1263   - author={Dokponou, Yao Christian Hugues and Badirou, Omar Boladji Ad{\'e}bayo and Agada, Kp{\`e}gnon Nicaise and Dossou, M{\`e}hom{\`e} Wilfried and Lawson, Lat{\'e} Dzidoula and Ossaga, Madjoue Ars{\`e}ne D{\'e}sir{\'e} and Nyalundja, Arsene Daniel and de Paule Adjiou, Dognon Kossi Fran{\c{c}}ois and Lassissi, Katib Ulrich and Houndodjade, Sena Midas Credo and others},
1264   - journal={Journal of Clinical Neuroscience},
1265   - volume={113},
1266   - pages={70--76},
1267   - year={2023},
1268   - publisher={Elsevier}
  1132 + title = {Transcranial doppler in the non-invasive estimation of intracranial pressure in traumatic brain injury compared to other non-invasive methods in lower-middle income countries: Systematic review and meta-analysis},
  1133 + author = {Dokponou, Yao Christian Hugues and Badirou, Omar Boladji Ad{\'e}bayo and Agada, Kp{\`e}gnon Nicaise and Dossou, M{\`e}hom{\`e} Wilfried and Lawson, Lat{\'e} Dzidoula and Ossaga, Madjoue Ars{\`e}ne D{\'e}sir{\'e} and Nyalundja, Arsene Daniel and de Paule Adjiou, Dognon Kossi Fran{\c{c}}ois and Lassissi, Katib Ulrich and Houndodjade, Sena Midas Credo and others},
  1134 + year = 2023,
  1135 + journal = {Journal of Clinical Neuroscience},
  1136 + publisher = {Elsevier},
  1137 + volume = 113,
  1138 + pages = {70--76}
1269 1139 }
1270   -
1271 1140 @article{kartal2024define,
1272   - title={How to define and meet blood pressure targets after traumatic brain injury: a narrative review},
1273   - author={Kartal, Ahmet and Robba, Chiara and Helmy, Adel and Wolf, Stefan and Aries, Marcel JH},
1274   - journal={Neurocritical Care},
1275   - volume={41},
1276   - number={2},
1277   - pages={369--385},
1278   - year={2024},
1279   - publisher={Springer}
  1141 + title = {How to define and meet blood pressure targets after traumatic brain injury: a narrative review},
  1142 + author = {Kartal, Ahmet and Robba, Chiara and Helmy, Adel and Wolf, Stefan and Aries, Marcel JH},
  1143 + year = 2024,
  1144 + journal = {Neurocritical Care},
  1145 + publisher = {Springer},
  1146 + volume = 41,
  1147 + number = 2,
  1148 + pages = {369--385}
1280 1149 }
1281   -
1282 1150 @article{vu2024monitoring,
1283   - title={Monitoring of cerebral blood flow autoregulation: physiologic basis, measurement, and clinical implications},
1284   - author={Vu, Eric L and Brown, Charles H and Brady, Kenneth M and Hogue, Charles W},
1285   - journal={British journal of anaesthesia},
1286   - volume={132},
1287   - number={6},
1288   - pages={1260--1273},
1289   - year={2024},
1290   - publisher={Elsevier}
  1151 + title = {Monitoring of cerebral blood flow autoregulation: physiologic basis, measurement, and clinical implications},
  1152 + author = {Vu, Eric L and Brown, Charles H and Brady, Kenneth M and Hogue, Charles W},
  1153 + year = 2024,
  1154 + journal = {British journal of anaesthesia},
  1155 + publisher = {Elsevier},
  1156 + volume = 132,
  1157 + number = 6,
  1158 + pages = {1260--1273}
1291 1159 }
1292   -
1293 1160 @article{czosnyka2022pro,
1294   - title={Pro-Con debate: the clinical (ir) relevance of the lower limit of cerebral autoregulation for anesthesiologists},
1295   - author={Czosnyka, Marek and Santarius, Thomas and Donnelly, Joseph and van den Dool, Rokus EC and Weiland, Nicolaas H Sperna},
1296   - journal={Anesthesia \& Analgesia},
1297   - volume={135},
1298   - number={4},
1299   - pages={734--743},
1300   - year={2022},
1301   - publisher={LWW}
  1161 + title = {Pro-Con debate: the clinical (ir) relevance of the lower limit of cerebral autoregulation for anesthesiologists},
  1162 + author = {Czosnyka, Marek and Santarius, Thomas and Donnelly, Joseph and van den Dool, Rokus EC and Weiland, Nicolaas H Sperna},
  1163 + year = 2022,
  1164 + journal = {Anesthesia \& Analgesia},
  1165 + publisher = {LWW},
  1166 + volume = 135,
  1167 + number = 4,
  1168 + pages = {734--743}
1302 1169 }
1303   -
1304 1170 %%% Autorégulation %%%
1305   -
1306 1171 @article{powers1985cerebral,
1307   - title={Cerebral blood flow and cerebral metabolic rate of oxygen requirements for cerebral function and viability in humans},
1308   - author={Powers, William J and Grubb Jr, Robert L and Darriet, Danielle and Raichle, Marcus E},
1309   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1310   - volume={5},
1311   - number={4},
1312   - pages={600--608},
1313   - year={1985},
1314   - publisher={SAGE Publications Sage UK: London, England}
  1172 + title = {Cerebral blood flow and cerebral metabolic rate of oxygen requirements for cerebral function and viability in humans},
  1173 + author = {Powers, William J and Grubb Jr, Robert L and Darriet, Danielle and Raichle, Marcus E},
  1174 + year = 1985,
  1175 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1176 + publisher = {SAGE Publications Sage UK: London, England},
  1177 + volume = 5,
  1178 + number = 4,
  1179 + pages = {600--608}
1315 1180 }
1316   -
1317 1181 @article{williams1989reference,
1318   - title={Reference values for resting blood flow to organs of man},
1319   - author={Williams, LR and Leggett, RW},
1320   - journal={Clinical Physics and Physiological Measurement},
1321   - volume={10},
1322   - number={3},
1323   - pages={187},
1324   - year={1989},
1325   - publisher={IOP Publishing}
  1182 + title = {Reference values for resting blood flow to organs of man},
  1183 + author = {Williams, LR and Leggett, RW},
  1184 + year = 1989,
  1185 + journal = {Clinical Physics and Physiological Measurement},
  1186 + publisher = {IOP Publishing},
  1187 + volume = 10,
  1188 + number = 3,
  1189 + pages = 187
1326 1190 }
1327   -
1328 1191 @article{gomez2025individualized,
1329   - title={Individualized autoregulation-guided arterial blood pressure management in neurocritical care},
1330   - author={Gomez, Jonathan R and Bhende, Bhagyashri U and Mathur, Rohan and Gonzalez, L Fernando and Shah, Vishank A},
1331   - journal={Neurotherapeutics},
1332   - pages={e00526},
1333   - year={2025},
1334   - publisher={Elsevier}
  1192 + title = {Individualized autoregulation-guided arterial blood pressure management in neurocritical care},
  1193 + author = {Gomez, Jonathan R and Bhende, Bhagyashri U and Mathur, Rohan and Gonzalez, L Fernando and Shah, Vishank A},
  1194 + year = 2025,
  1195 + journal = {Neurotherapeutics},
  1196 + publisher = {Elsevier},
  1197 + pages = {e00526}
1335 1198 }
1336   -
1337 1199 @article{rivera2017cerebral,
1338   - title={Cerebral autoregulation-oriented therapy at the bedside},
1339   - author={Rivera-Lara, Lucia and Zorrilla-Vaca, Andres and Geocadin, Romergryko G and Healy, Ryan J and Ziai, Wendy and Mirski, Marek A},
1340   - journal={Anesthesiology},
1341   - volume={126},
1342   - number={6},
1343   - pages={1187--1199},
1344   - year={2017},
1345   - publisher={Wolters Kluwer}
  1200 + title = {Cerebral autoregulation-oriented therapy at the bedside},
  1201 + author = {Rivera-Lara, Lucia and Zorrilla-Vaca, Andres and Geocadin, Romergryko G and Healy, Ryan J and Ziai, Wendy and Mirski, Marek A},
  1202 + year = 2017,
  1203 + journal = {Anesthesiology},
  1204 + publisher = {Wolters Kluwer},
  1205 + volume = 126,
  1206 + number = 6,
  1207 + pages = {1187--1199}
1346 1208 }
1347   -
1348 1209 @article{willie2014integrative,
1349   - title={Integrative regulation of human brain blood flow},
1350   - author={Willie, Christopher K and Tzeng, Yu-Chieh and Fisher, Joseph A and Ainslie, Philip N},
1351   - journal={The Journal of physiology},
1352   - volume={592},
1353   - number={5},
1354   - pages={841--859},
1355   - year={2014},
1356   - publisher={Wiley Online Library}
  1210 + title = {Integrative regulation of human brain blood flow},
  1211 + author = {Willie, Christopher K and Tzeng, Yu-Chieh and Fisher, Joseph A and Ainslie, Philip N},
  1212 + year = 2014,
  1213 + journal = {The Journal of physiology},
  1214 + publisher = {Wiley Online Library},
  1215 + volume = 592,
  1216 + number = 5,
  1217 + pages = {841--859}
1357 1218 }
1358   -
1359 1219 @article{dietvorst2024development,
1360   - title={Development of a piglet model for cerebrovascular autoregulation assessment with altered PaCO2},
1361   - author={Dietvorst, Sofie and Desloovere, Veerle and Meyfroidt, Geert and Depreitere, Bart},
1362   - journal={Brain and Spine},
1363   - volume={4},
1364   - pages={102833},
1365   - year={2024},
1366   - publisher={Elsevier}
  1220 + title = {Development of a piglet model for cerebrovascular autoregulation assessment with altered PaCO2},
  1221 + author = {Dietvorst, Sofie and Desloovere, Veerle and Meyfroidt, Geert and Depreitere, Bart},
  1222 + year = 2024,
  1223 + journal = {Brain and Spine},
  1224 + publisher = {Elsevier},
  1225 + volume = 4,
  1226 + pages = 102833
1367 1227 }
1368   -
1369 1228 @article{jackson2016arteriolar,
1370   - title={Arteriolar oxygen reactivity: where is the sensor and what is the mechanism of action?},
1371   - author={Jackson, William F},
1372   - journal={The Journal of Physiology},
1373   - volume={594},
1374   - number={18},
1375   - pages={5055--5077},
1376   - year={2016},
1377   - publisher={Wiley Online Library}
  1229 + title = {Arteriolar oxygen reactivity: where is the sensor and what is the mechanism of action?},
  1230 + author = {Jackson, William F},
  1231 + year = 2016,
  1232 + journal = {The Journal of Physiology},
  1233 + publisher = {Wiley Online Library},
  1234 + volume = 594,
  1235 + number = 18,
  1236 + pages = {5055--5077}
1378 1237 }
1379   -
1380 1238 @article{beaudin2017human,
1381   - title={Human cerebral blood flow control during hypoxia: focus on chronic pulmonary obstructive disease and obstructive sleep apnea},
1382   - author={Beaudin, Andrew E and Hartmann, Sara E and Pun, Matiram and Poulin, Marc J},
1383   - journal={Journal of Applied Physiology},
1384   - volume={123},
1385   - number={5},
1386   - pages={1350--1361},
1387   - year={2017},
1388   - publisher={American Physiological Society Bethesda, MD}
  1239 + title = {Human cerebral blood flow control during hypoxia: focus on chronic pulmonary obstructive disease and obstructive sleep apnea},
  1240 + author = {Beaudin, Andrew E and Hartmann, Sara E and Pun, Matiram and Poulin, Marc J},
  1241 + year = 2017,
  1242 + journal = {Journal of Applied Physiology},
  1243 + publisher = {American Physiological Society Bethesda, MD},
  1244 + volume = 123,
  1245 + number = 5,
  1246 + pages = {1350--1361}
1389 1247 }
1390   -
1391 1248 @article{ashby2021endothelial,
1392   - title={Endothelial control of cerebral blood flow},
1393   - author={Ashby, Julianne W and Mack, Julia J},
1394   - journal={The American Journal of Pathology},
1395   - volume={191},
1396   - number={11},
1397   - pages={1906--1916},
1398   - year={2021},
1399   - publisher={Elsevier}
  1249 + title = {Endothelial control of cerebral blood flow},
  1250 + author = {Ashby, Julianne W and Mack, Julia J},
  1251 + year = 2021,
  1252 + journal = {The American Journal of Pathology},
  1253 + publisher = {Elsevier},
  1254 + volume = 191,
  1255 + number = 11,
  1256 + pages = {1906--1916}
1400 1257 }
1401   -
1402 1258 @article{phillips2016neurovascular,
1403   - title={Neurovascular coupling in humans: physiology, methodological advances and clinical implications},
1404   - author={Phillips, Aaron A and Chan, Franco HN and Zheng, Mei Mu Zi and Krassioukov, Andrei V and Ainslie, Philip N},
1405   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1406   - volume={36},
1407   - number={4},
1408   - pages={647--664},
1409   - year={2016},
1410   - publisher={SAGE Publications Sage UK: London, England}
  1259 + title = {Neurovascular coupling in humans: physiology, methodological advances and clinical implications},
  1260 + author = {Phillips, Aaron A and Chan, Franco HN and Zheng, Mei Mu Zi and Krassioukov, Andrei V and Ainslie, Philip N},
  1261 + year = 2016,
  1262 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1263 + publisher = {SAGE Publications Sage UK: London, England},
  1264 + volume = 36,
  1265 + number = 4,
  1266 + pages = {647--664}
1411 1267 }
1412   -
1413 1268 @article{hamner2014relative,
1414   - title={Relative contributions of sympathetic, cholinergic, and myogenic mechanisms to cerebral autoregulation},
1415   - author={Hamner, JW and Tan, Can Ozan},
1416   - journal={Stroke},
1417   - volume={45},
1418   - number={6},
1419   - pages={1771--1777},
1420   - year={2014},
1421   - publisher={Lippincott Williams \& Wilkins Hagerstown, MD}
  1269 + title = {Relative contributions of sympathetic, cholinergic, and myogenic mechanisms to cerebral autoregulation},
  1270 + author = {Hamner, JW and Tan, Can Ozan},
  1271 + year = 2014,
  1272 + journal = {Stroke},
  1273 + publisher = {Lippincott Williams \& Wilkins Hagerstown, MD},
  1274 + volume = 45,
  1275 + number = 6,
  1276 + pages = {1771--1777}
1422 1277 }
1423   -
1424   -
1425 1278 @article{halpern1984mechanical,
1426   - title={Mechanical behavior of pressurized in vitro prearteriolar vessels determined with a video system},
1427   - author={Halpern, William and Osol, George and Coy, George S},
1428   - journal={Annals of biomedical engineering},
1429   - volume={12},
1430   - pages={463--479},
1431   - year={1984},
1432   - publisher={Springer}
  1279 + title = {Mechanical behavior of pressurized in vitro prearteriolar vessels determined with a video system},
  1280 + author = {Halpern, William and Osol, George and Coy, George S},
  1281 + year = 1984,
  1282 + journal = {Annals of biomedical engineering},
  1283 + publisher = {Springer},
  1284 + volume = 12,
  1285 + pages = {463--479}
1433 1286 }
1434   -
1435 1287 @article{lidington2018cerebral,
1436   - title={Cerebral artery myogenic reactivity: the next frontier in developing effective interventions for subarachnoid hemorrhage},
1437   - author={Lidington, Darcy and Kroetsch, Jeffrey T and Bolz, Steffen-Sebastian},
1438   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1439   - volume={38},
1440   - number={1},
1441   - pages={17--37},
1442   - year={2018},
1443   - publisher={SAGE Publications Sage UK: London, England}
  1288 + title = {Cerebral artery myogenic reactivity: the next frontier in developing effective interventions for subarachnoid hemorrhage},
  1289 + author = {Lidington, Darcy and Kroetsch, Jeffrey T and Bolz, Steffen-Sebastian},
  1290 + year = 2018,
  1291 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1292 + publisher = {SAGE Publications Sage UK: London, England},
  1293 + volume = 38,
  1294 + number = 1,
  1295 + pages = {17--37}
1444 1296 }
1445   -
1446 1297 @article{jackson2021calcium,
1447   - title={Calcium-dependent ion channels and the regulation of arteriolar myogenic tone},
1448   - author={Jackson, William F},
1449   - journal={Frontiers in physiology},
1450   - volume={12},
1451   - pages={770450},
1452   - year={2021},
1453   - publisher={Frontiers Media SA}
  1298 + title = {Calcium-dependent ion channels and the regulation of arteriolar myogenic tone},
  1299 + author = {Jackson, William F},
  1300 + year = 2021,
  1301 + journal = {Frontiers in physiology},
  1302 + publisher = {Frontiers Media SA},
  1303 + volume = 12,
  1304 + pages = 770450
1454 1305 }
1455   -
1456 1306 @article{claassen2016transfer,
1457   - title={Transfer function analysis of dynamic cerebral autoregulation: a white paper from the International Cerebral Autoregulation Research Network},
1458   - author={Claassen, Jurgen AHR and Meel-van den Abeelen, Aisha SS and Simpson, David M and Panerai, Ronney B and International Cerebral Autoregulation Research Network (CARNet)},
1459   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1460   - volume={36},
1461   - number={4},
1462   - pages={665--680},
1463   - year={2016},
1464   - publisher={SAGE Publications Sage UK: London, England}
  1307 + title = {Transfer function analysis of dynamic cerebral autoregulation: a white paper from the International Cerebral Autoregulation Research Network},
  1308 + author = {Claassen, Jurgen AHR and Meel-van den Abeelen, Aisha SS and Simpson, David M and Panerai, Ronney B and International Cerebral Autoregulation Research Network (CARNet)},
  1309 + year = 2016,
  1310 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1311 + publisher = {SAGE Publications Sage UK: London, England},
  1312 + volume = 36,
  1313 + number = 4,
  1314 + pages = {665--680}
1465 1315 }
1466   -
1467 1316 @article{panerai2023transfer,
1468   - title={Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update},
1469   - author={Panerai, Ronney B and Brassard, Patrice and Burma, Joel S and Castro, Pedro and Claassen, Jurgen AHR and van Lieshout, Johannes J and Liu, Jia and Lucas, Samuel JE and Minhas, Jatinder S and Mitsis, Georgios D and others},
1470   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1471   - volume={43},
1472   - number={1},
1473   - pages={3--25},
1474   - year={2023},
1475   - publisher={SAGE Publications Sage UK: London, England}
  1317 + title = {Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update},
  1318 + author = {Panerai, Ronney B and Brassard, Patrice and Burma, Joel S and Castro, Pedro and Claassen, Jurgen AHR and van Lieshout, Johannes J and Liu, Jia and Lucas, Samuel JE and Minhas, Jatinder S and Mitsis, Georgios D and others},
  1319 + year = 2023,
  1320 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1321 + publisher = {SAGE Publications Sage UK: London, England},
  1322 + volume = 43,
  1323 + number = 1,
  1324 + pages = {3--25}
1476 1325 }
1477   -
1478 1326 @article{howells2025vasomotion,
1479   - title={Vasomotion and Cerebral Blood Flow in Patients With Traumatic Brain Injury and Subarachnoid Hemorrhage: Cerebrovascular Autoregulation Versus Autonomic Control},
1480   - author={Howells, Timothy and H{\aa}nell, Anders and Svedung Wettervik, Teodor and Enblad, Per},
1481   - journal={Journal of Neurotrauma},
1482   - volume={42},
1483   - number={7-8},
1484   - pages={700--713},
1485   - year={2025},
1486   - publisher={Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…}
  1327 + title = {Vasomotion and Cerebral Blood Flow in Patients With Traumatic Brain Injury and Subarachnoid Hemorrhage: Cerebrovascular Autoregulation Versus Autonomic Control},
  1328 + author = {Howells, Timothy and H{\aa}nell, Anders and Svedung Wettervik, Teodor and Enblad, Per},
  1329 + year = 2025,
  1330 + journal = {Journal of Neurotrauma},
  1331 + publisher = {Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…},
  1332 + volume = 42,
  1333 + number = {7-8},
  1334 + pages = {700--713}
1487 1335 }
1488   -
1489 1336 @article{paulson1990cerebral,
1490   - title={Cerebral autoregulation},
1491   - author={Paulson, OB and Strandgaard, S and Edvinsson, L},
1492   - journal={Cerebrovascular and brain metabolism reviews},
1493   - volume={2},
1494   - number={2},
1495   - pages={161--192},
1496   - year={1990}
  1337 + title = {Cerebral autoregulation},
  1338 + author = {Paulson, OB and Strandgaard, S and Edvinsson, L},
  1339 + year = 1990,
  1340 + journal = {Cerebrovascular and brain metabolism reviews},
  1341 + volume = 2,
  1342 + number = 2,
  1343 + pages = {161--192}
1497 1344 }
1498   -
1499   -
1500 1345 @article{sorrentino2011critical,
1501   - title={Critical thresholds for transcranial Doppler indices of cerebral autoregulation in traumatic brain injury},
1502   - author={Sorrentino, Enrico and Budohoski, Karol P and Kasprowicz, Magdalena and Smielewski, Peter and Matta, Basil and Pickard, John D and Czosnyka, Marek},
1503   - journal={Neurocritical care},
1504   - volume={14},
1505   - pages={188--193},
1506   - year={2011},
1507   - publisher={Springer}
  1346 + title = {Critical thresholds for transcranial Doppler indices of cerebral autoregulation in traumatic brain injury},
  1347 + author = {Sorrentino, Enrico and Budohoski, Karol P and Kasprowicz, Magdalena and Smielewski, Peter and Matta, Basil and Pickard, John D and Czosnyka, Marek},
  1348 + year = 2011,
  1349 + journal = {Neurocritical care},
  1350 + publisher = {Springer},
  1351 + volume = 14,
  1352 + pages = {188--193}
1508 1353 }
1509   -
1510 1354 @article{czosnyka1996monitoring,
1511   - title={Monitoring of cerebral autoregulation in head-injured patients},
1512   - author={Czosnyka, Marek and Smielewski, Piotr and Kirkpatrick, Peter and Menon, David K and Pickard, John D},
1513   - journal={Stroke},
1514   - volume={27},
1515   - number={10},
1516   - pages={1829--1834},
1517   - year={1996},
1518   - publisher={Lippincott Williams \& Wilkins}
  1355 + title = {Monitoring of cerebral autoregulation in head-injured patients},
  1356 + author = {Czosnyka, Marek and Smielewski, Piotr and Kirkpatrick, Peter and Menon, David K and Pickard, John D},
  1357 + year = 1996,
  1358 + journal = {Stroke},
  1359 + publisher = {Lippincott Williams \& Wilkins},
  1360 + volume = 27,
  1361 + number = 10,
  1362 + pages = {1829--1834}
1519 1363 }
1520   -
1521 1364 @article{lang2002continuous,
1522   - title={Continuous monitoring of cerebrovascular autoregulation: a validation study},
1523   - author={Lang, EW and Mehdorn, HM and Dorsch, NWC and Czosnyka, Marek},
1524   - journal={Journal of Neurology, Neurosurgery \& Psychiatry},
1525   - volume={72},
1526   - number={5},
1527   - pages={583--586},
1528   - year={2002},
1529   - publisher={BMJ Publishing Group Ltd}
  1365 + title = {Continuous monitoring of cerebrovascular autoregulation: a validation study},
  1366 + author = {Lang, EW and Mehdorn, HM and Dorsch, NWC and Czosnyka, Marek},
  1367 + year = 2002,
  1368 + journal = {Journal of Neurology, Neurosurgery \& Psychiatry},
  1369 + publisher = {BMJ Publishing Group Ltd},
  1370 + volume = 72,
  1371 + number = 5,
  1372 + pages = {583--586}
1530 1373 }
1531   -
1532 1374 @article{schmidt2003symmetry,
1533   - title={Symmetry of cerebral hemodynamic indices derived from bilateral transcranial Doppler},
1534   - author={Schmidt, Eric A and Piechnik, Stefan K and Smielewski, Piotr and Raabe, Andreas and Matta, Basil F and Czosnyka, Marek},
1535   - journal={Journal of Neuroimaging},
1536   - volume={13},
1537   - number={3},
1538   - pages={248--254},
1539   - year={2003},
1540   - publisher={Wiley Online Library}
  1375 + title = {Symmetry of cerebral hemodynamic indices derived from bilateral transcranial Doppler},
  1376 + author = {Schmidt, Eric A and Piechnik, Stefan K and Smielewski, Piotr and Raabe, Andreas and Matta, Basil F and Czosnyka, Marek},
  1377 + year = 2003,
  1378 + journal = {Journal of Neuroimaging},
  1379 + publisher = {Wiley Online Library},
  1380 + volume = 13,
  1381 + number = 3,
  1382 + pages = {248--254}
1541 1383 }
1542   -
1543 1384 @article{olsen2022reliability,
1544   - title={Reliability and validity of the mean flow index (Mx) for assessing cerebral autoregulation in humans: a systematic review of the methodology},
1545   - author={Olsen, Markus Harboe and Riberholt, Christian Gunge and Mehlsen, Jesper and Berg, Ronan MG and M{\o}ller, Kirsten},
1546   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1547   - volume={42},
1548   - number={1},
1549   - pages={27--38},
1550   - year={2022},
1551   - publisher={SAGE Publications Sage UK: London, England}
  1385 + title = {Reliability and validity of the mean flow index (Mx) for assessing cerebral autoregulation in humans: a systematic review of the methodology},
  1386 + author = {Olsen, Markus Harboe and Riberholt, Christian Gunge and Mehlsen, Jesper and Berg, Ronan MG and M{\o}ller, Kirsten},
  1387 + year = 2022,
  1388 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1389 + publisher = {SAGE Publications Sage UK: London, England},
  1390 + volume = 42,
  1391 + number = 1,
  1392 + pages = {27--38}
1552 1393 }
1553   -
1554 1394 @article{budohoski2012monitoring,
1555   - title={Monitoring cerebral autoregulation after head injury. Which component of transcranial Doppler flow velocity is optimal?},
1556   - author={Budohoski, Karol P and Reinhard, Matthias and Aries, Marcel JH and Czosnyka, Zofia and Smielewski, Peter and Pickard, John D and Kirkpatrick, Peter J and Czosnyka, Marek},
1557   - journal={Neurocritical care},
1558   - volume={17},
1559   - pages={211--218},
1560   - year={2012},
1561   - publisher={Springer}
  1395 + title = {Monitoring cerebral autoregulation after head injury. Which component of transcranial Doppler flow velocity is optimal?},
  1396 + author = {Budohoski, Karol P and Reinhard, Matthias and Aries, Marcel JH and Czosnyka, Zofia and Smielewski, Peter and Pickard, John D and Kirkpatrick, Peter J and Czosnyka, Marek},
  1397 + year = 2012,
  1398 + journal = {Neurocritical care},
  1399 + publisher = {Springer},
  1400 + volume = 17,
  1401 + pages = {211--218}
1562 1402 }
1563   -
1564 1403 @article{schmidt2016autoregulation,
1565   - title={Autoregulation monitoring and outcome prediction in neurocritical care patients: Does one index fit all?},
1566   - author={Schmidt, Bernhard and Reinhard, Matthias and Lezaic, Vesna and McLeod, Damian D and Weinhold, Marco and Mattes, Heinz and Klingelh{\"o}fer, J{\"u}rgen},
1567   - journal={Journal of clinical monitoring and computing},
1568   - volume={30},
1569   - pages={367--375},
1570   - year={2016},
1571   - publisher={Springer}
  1404 + title = {Autoregulation monitoring and outcome prediction in neurocritical care patients: Does one index fit all?},
  1405 + author = {Schmidt, Bernhard and Reinhard, Matthias and Lezaic, Vesna and McLeod, Damian D and Weinhold, Marco and Mattes, Heinz and Klingelh{\"o}fer, J{\"u}rgen},
  1406 + year = 2016,
  1407 + journal = {Journal of clinical monitoring and computing},
  1408 + publisher = {Springer},
  1409 + volume = 30,
  1410 + pages = {367--375}
1572 1411 }
1573   -
1574 1412 @article{kostoglou2024time,
1575   - title={Time-domain methods for quantifying dynamic cerebral blood flow autoregulation: Review and recommendations. A white paper from the Cerebrovascular Research Network (CARNet)},
1576   - author={Kostoglou, Kyriaki and Bello-Robles, Felipe and Brassard, Patrice and Chacon, Max and Claassen, Jurgen AHR and Czosnyka, Marek and Elting, Jan-Willem and Hu, Kun and Labrecque, Lawrence and Liu, Jia and others},
1577   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1578   - volume={44},
1579   - number={9},
1580   - pages={1480--1514},
1581   - year={2024},
1582   - publisher={SAGE Publications Sage UK: London, England}
  1413 + title = {Time-domain methods for quantifying dynamic cerebral blood flow autoregulation: Review and recommendations. A white paper from the Cerebrovascular Research Network (CARNet)},
  1414 + author = {Kostoglou, Kyriaki and Bello-Robles, Felipe and Brassard, Patrice and Chacon, Max and Claassen, Jurgen AHR and Czosnyka, Marek and Elting, Jan-Willem and Hu, Kun and Labrecque, Lawrence and Liu, Jia and others},
  1415 + year = 2024,
  1416 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1417 + publisher = {SAGE Publications Sage UK: London, England},
  1418 + volume = 44,
  1419 + number = 9,
  1420 + pages = {1480--1514}
1583 1421 }
1584   -
1585 1422 @article{czosnyka1997continuous,
1586   - title={Continuous assessment of the cerebral vasomotor reactivity in head injury},
1587   - author={Czosnyka, Marek and Smielewski, Piotr and Kirkpatrick, Peter and Laing, Rodney J and Menon, David and Pickard, John D},
1588   - journal={Neurosurgery},
1589   - volume={41},
1590   - number={1},
1591   - pages={11--19},
1592   - year={1997},
1593   - publisher={LWW}
  1423 + title = {Continuous assessment of the cerebral vasomotor reactivity in head injury},
  1424 + author = {Czosnyka, Marek and Smielewski, Piotr and Kirkpatrick, Peter and Laing, Rodney J and Menon, David and Pickard, John D},
  1425 + year = 1997,
  1426 + journal = {Neurosurgery},
  1427 + publisher = {LWW},
  1428 + volume = 41,
  1429 + number = 1,
  1430 + pages = {11--19}
1594 1431 }
1595   -
1596 1432 @article{tsigaras2023pressure,
1597   - title={The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management},
1598   - author={Tsigaras, Zac A and Weeden, Mark and McNamara, Robert and Jeffcote, Toby and Udy, Andrew A and Anstey, James and Plummer, Mark and Bellapart, Judith and Chow, Andrew and Delaney, Anthony and others},
1599   - journal={Critical Care and Resuscitation},
1600   - volume={25},
1601   - number={4},
1602   - pages={229--236},
1603   - year={2023},
1604   - publisher={Elsevier}
  1433 + title = {The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management},
  1434 + author = {Tsigaras, Zac A and Weeden, Mark and McNamara, Robert and Jeffcote, Toby and Udy, Andrew A and Anstey, James and Plummer, Mark and Bellapart, Judith and Chow, Andrew and Delaney, Anthony and others},
  1435 + year = 2023,
  1436 + journal = {Critical Care and Resuscitation},
  1437 + publisher = {Elsevier},
  1438 + volume = 25,
  1439 + number = 4,
  1440 + pages = {229--236}
1605 1441 }
1606   -
1607 1442 @article{svedung2023autoregulatory,
1608   - title={Autoregulatory management in traumatic brain injury: the role of absolute pressure reactivity index values and optimal cerebral perfusion pressure curve shape},
1609   - author={Svedung Wettervik, Teodor and H{\aa}nell, Anders and Howells, Timothy and Lew{\'e}n, Anders and Enblad, Per},
1610   - journal={Journal of Neurotrauma},
1611   - volume={40},
1612   - number={21-22},
1613   - pages={2341--2352},
1614   - year={2023},
1615   - publisher={Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…}
  1443 + title = {Autoregulatory management in traumatic brain injury: the role of absolute pressure reactivity index values and optimal cerebral perfusion pressure curve shape},
  1444 + author = {Svedung Wettervik, Teodor and H{\aa}nell, Anders and Howells, Timothy and Lew{\'e}n, Anders and Enblad, Per},
  1445 + year = 2023,
  1446 + journal = {Journal of Neurotrauma},
  1447 + publisher = {Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…},
  1448 + volume = 40,
  1449 + number = {21-22},
  1450 + pages = {2341--2352}
1616 1451 }
1617   -
1618 1452 @inproceedings{trukhan2022effect,
1619   - title={Effect of pressure reactivity index calculation settings on the range of the optimal cerebral perfusion pressure},
1620   - author={Trukhan, Valeriia and Horakova, Lenka and Skola, Josef and Rozanek, Martin},
1621   - booktitle={2022 E-Health and Bioengineering Conference (EHB)},
1622   - pages={1--4},
1623   - year={2022},
1624   - organization={IEEE}
  1453 + title = {Effect of pressure reactivity index calculation settings on the range of the optimal cerebral perfusion pressure},
  1454 + author = {Trukhan, Valeriia and Horakova, Lenka and Skola, Josef and Rozanek, Martin},
  1455 + year = 2022,
  1456 + booktitle = {2022 E-Health and Bioengineering Conference (EHB)},
  1457 + pages = {1--4},
  1458 + organization = {IEEE}
1625 1459 }
1626   -
1627 1460 @article{burma2024systematic,
1628   - title={A systematic review, meta-analysis and meta-regression amalgamating the driven approaches used to quantify dynamic cerebral autoregulation},
1629   - author={Burma, Joel S and Roy, Marc-Antoine and Kennedy, Courtney M and Labrecque, Lawrence and Brassard, Patrice and Smirl, Jonathan D},
1630   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1631   - volume={44},
1632   - number={8},
1633   - pages={1271--1297},
1634   - year={2024},
1635   - publisher={SAGE Publications Sage UK: London, England}
  1461 + title = {A systematic review, meta-analysis and meta-regression amalgamating the driven approaches used to quantify dynamic cerebral autoregulation},
  1462 + author = {Burma, Joel S and Roy, Marc-Antoine and Kennedy, Courtney M and Labrecque, Lawrence and Brassard, Patrice and Smirl, Jonathan D},
  1463 + year = 2024,
  1464 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1465 + publisher = {SAGE Publications Sage UK: London, England},
  1466 + volume = 44,
  1467 + number = 8,
  1468 + pages = {1271--1297}
1636 1469 }
1637   -
1638 1470 @article{burma2021recording,
1639   - title={What recording duration is required to provide physiologically valid and reliable dynamic cerebral autoregulation transfer functional analysis estimates?},
1640   - author={Burma, Joel S and Miutz, Lauren N and Newel, Kailey T and Labrecque, Lawrence and Drapeau, Audrey and Brassard, Patrice and Copeland, Paige and Macaulay, Alannah and Smirl, Jonathan D},
1641   - journal={Physiological Measurement},
1642   - volume={42},
1643   - number={4},
1644   - pages={044002},
1645   - year={2021},
1646   - publisher={IOP Publishing}
  1471 + title = {What recording duration is required to provide physiologically valid and reliable dynamic cerebral autoregulation transfer functional analysis estimates?},
  1472 + author = {Burma, Joel S and Miutz, Lauren N and Newel, Kailey T and Labrecque, Lawrence and Drapeau, Audrey and Brassard, Patrice and Copeland, Paige and Macaulay, Alannah and Smirl, Jonathan D},
  1473 + year = 2021,
  1474 + journal = {Physiological Measurement},
  1475 + publisher = {IOP Publishing},
  1476 + volume = 42,
  1477 + number = 4,
  1478 + pages = {044002}
1647 1479 }
1648   -
1649 1480 @article{needham2017cerebral,
1650   - title={Cerebral perfusion pressure targets individualized to pressure-reactivity index in moderate to severe traumatic brain injury: a systematic review},
1651   - author={Needham, Edward and McFadyen, Charles and Newcombe, Virginia and Synnot, Anneliese J and Czosnyka, Marek and Menon, David},
1652   - journal={Journal of neurotrauma},
1653   - volume={34},
1654   - number={5},
1655   - pages={963--970},
1656   - year={2017},
1657   - publisher={Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA}
  1481 + title = {Cerebral perfusion pressure targets individualized to pressure-reactivity index in moderate to severe traumatic brain injury: a systematic review},
  1482 + author = {Needham, Edward and McFadyen, Charles and Newcombe, Virginia and Synnot, Anneliese J and Czosnyka, Marek and Menon, David},
  1483 + year = 2017,
  1484 + journal = {Journal of neurotrauma},
  1485 + publisher = {Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA},
  1486 + volume = 34,
  1487 + number = 5,
  1488 + pages = {963--970}
1658 1489 }
1659   -
1660 1490 @article{depreitere2021cerebrovascular,
1661   - title={Cerebrovascular autoregulation monitoring in the management of adult severe traumatic brain injury: a Delphi consensus of clinicians},
1662   - author={Depreitere, B and Citerio, G and Smith, M and Adelson, P David and Aries, MJ and Bleck, TP and Bouzat, Pierre and Chesnut, R and De Sloovere, V and Diringer, M and others},
1663   - journal={Neurocritical care},
1664   - volume={34},
1665   - pages={731--738},
1666   - year={2021},
1667   - publisher={Springer}
  1491 + title = {Cerebrovascular autoregulation monitoring in the management of adult severe traumatic brain injury: a Delphi consensus of clinicians},
  1492 + author = {Depreitere, B and Citerio, G and Smith, M and Adelson, P David and Aries, MJ and Bleck, TP and Bouzat, Pierre and Chesnut, R and De Sloovere, V and Diringer, M and others},
  1493 + year = 2021,
  1494 + journal = {Neurocritical care},
  1495 + publisher = {Springer},
  1496 + volume = 34,
  1497 + pages = {731--738}
1668 1498 }
1669   -
1670 1499 @book{beqiri2021optimal,
1671   - title={Optimal cerebral perfusion pressure assessed with a multi-window weighted approach adapted for prospective use: a validation study},
1672   - author={Beqiri, Erta and Ercole, Ari and Aries, Marcel J and Cabeleira, Manuel and Czigler, Andras and Liberti, Annalisa and Tas, Jeanette and Donnelly, Joseph and Liu, Xiuyun and Fedriga, Marta and others},
1673   - year={2021},
1674   - publisher={Springer}
  1500 + title = {Optimal cerebral perfusion pressure assessed with a multi-window weighted approach adapted for prospective use: a validation study},
  1501 + author = {Beqiri, Erta and Ercole, Ari and Aries, Marcel J and Cabeleira, Manuel and Czigler, Andras and Liberti, Annalisa and Tas, Jeanette and Donnelly, Joseph and Liu, Xiuyun and Fedriga, Marta and others},
  1502 + year = 2021,
  1503 + publisher = {Springer}
1675 1504 }
1676   -
1677 1505 @article{aries2012continuous,
1678   - title={Continuous monitoring of cerebrovascular reactivity using pulse waveform of intracranial pressure},
1679   - author={Aries, Marcel JH and Czosnyka, Marek and Budohoski, Karol P and Kolias, Angelos G and Radolovich, Danila K and Lavinio, Andrea and Pickard, John D and Smielewski, Peter},
1680   - journal={Neurocritical care},
1681   - volume={17},
1682   - pages={67--76},
1683   - year={2012},
1684   - publisher={Springer}
  1506 + title = {Continuous monitoring of cerebrovascular reactivity using pulse waveform of intracranial pressure},
  1507 + author = {Aries, Marcel JH and Czosnyka, Marek and Budohoski, Karol P and Kolias, Angelos G and Radolovich, Danila K and Lavinio, Andrea and Pickard, John D and Smielewski, Peter},
  1508 + year = 2012,
  1509 + journal = {Neurocritical care},
  1510 + publisher = {Springer},
  1511 + volume = 17,
  1512 + pages = {67--76}
1685 1513 }
1686   -
1687 1514 @article{donnelly2017individualizing,
1688   - title={Individualizing thresholds of cerebral perfusion pressure using estimated limits of autoregulation},
1689   - author={Donnelly, Joseph and Czosnyka, Marek and Adams, Hadie and Robba, Chiara and Steiner, Luzius A and Cardim, Danilo and Cabella, Brenno and Liu, Xiuyun and Ercole, Ari and Hutchinson, Peter John and others},
1690   - journal={Critical care medicine},
1691   - volume={45},
1692   - number={9},
1693   - pages={1464--1471},
1694   - year={2017},
1695   - publisher={LWW}
  1515 + title = {Individualizing thresholds of cerebral perfusion pressure using estimated limits of autoregulation},
  1516 + author = {Donnelly, Joseph and Czosnyka, Marek and Adams, Hadie and Robba, Chiara and Steiner, Luzius A and Cardim, Danilo and Cabella, Brenno and Liu, Xiuyun and Ercole, Ari and Hutchinson, Peter John and others},
  1517 + year = 2017,
  1518 + journal = {Critical care medicine},
  1519 + publisher = {LWW},
  1520 + volume = 45,
  1521 + number = 9,
  1522 + pages = {1464--1471}
1696 1523 }
1697   -
1698 1524 @article{kramer2019continuous,
1699   - title={Continuous assessment of “optimal” cerebral perfusion pressure in traumatic brain injury: a cohort study of feasibility, reliability, and relation to outcome},
1700   - author={Kramer, Andreas H and Couillard, Philippe L and Zygun, David A and Aries, Marcel J and Gallagher, Clare N},
1701   - journal={Neurocritical care},
1702   - volume={30},
1703   - pages={51--61},
1704   - year={2019},
1705   - publisher={Springer}
  1525 + title = {Continuous assessment of “optimal” cerebral perfusion pressure in traumatic brain injury: a cohort study of feasibility, reliability, and relation to outcome},
  1526 + author = {Kramer, Andreas H and Couillard, Philippe L and Zygun, David A and Aries, Marcel J and Gallagher, Clare N},
  1527 + year = 2019,
  1528 + journal = {Neurocritical care},
  1529 + publisher = {Springer},
  1530 + volume = 30,
  1531 + pages = {51--61}
1706 1532 }
1707   -
1708 1533 @article{bogli2025cerebral,
1709   - title={Cerebral perfusion pressure targets after traumatic brain injury: a reappraisal},
1710   - author={B{\"o}gli, Stefan Yu and Olakorede, Ihsane and Beqiri, Erta and Chen, Xuhang and Lavinio, Andrea and Hutchinson, Peter and Smielewski, Peter},
1711   - journal={Critical Care},
1712   - volume={29},
1713   - number={1},
1714   - pages={1--14},
1715   - year={2025},
1716   - publisher={Springer}
  1534 + title = {Cerebral perfusion pressure targets after traumatic brain injury: a reappraisal},
  1535 + author = {B{\"o}gli, Stefan Yu and Olakorede, Ihsane and Beqiri, Erta and Chen, Xuhang and Lavinio, Andrea and Hutchinson, Peter and Smielewski, Peter},
  1536 + year = 2025,
  1537 + journal = {Critical Care},
  1538 + publisher = {Springer},
  1539 + volume = 29,
  1540 + number = 1,
  1541 + pages = {1--14}
1717 1542 }
1718   -
1719 1543 @article{tas2021targeting,
1720   - title={Targeting autoregulation-guided cerebral perfusion pressure after traumatic brain injury (COGiTATE): a feasibility randomized controlled clinical trial},
1721   - author={Tas, Jeanette and Beqiri, Erta and van Kaam, Ruud C and Czosnyka, Marek and Donnelly, Joseph and Haeren, Roel H and van der Horst, Iwan CC and Hutchinson, Peter J and van Kuijk, Sander MJ and Liberti, Analisa L and others},
1722   - journal={Journal of neurotrauma},
1723   - volume={38},
1724   - number={20},
1725   - pages={2790--2800},
1726   - year={2021},
1727   - publisher={Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…}
  1544 + title = {Targeting autoregulation-guided cerebral perfusion pressure after traumatic brain injury (COGiTATE): a feasibility randomized controlled clinical trial},
  1545 + author = {Tas, Jeanette and Beqiri, Erta and van Kaam, Ruud C and Czosnyka, Marek and Donnelly, Joseph and Haeren, Roel H and van der Horst, Iwan CC and Hutchinson, Peter J and van Kuijk, Sander MJ and Liberti, Analisa L and others},
  1546 + year = 2021,
  1547 + journal = {Journal of neurotrauma},
  1548 + publisher = {Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…},
  1549 + volume = 38,
  1550 + number = 20,
  1551 + pages = {2790--2800}
1728 1552 }
1729   -
1730 1553 @article{liu2017cerebrovascular,
1731   - title={Cerebrovascular pressure reactivity monitoring using wavelet analysis in traumatic brain injury patients: a retrospective study},
1732   - author={Liu, Xiuyun and Donnelly, Joseph and Czosnyka, Marek and Aries, Marcel JH and Brady, Ken and Cardim, Danilo and Robba, Chiara and Cabeleira, Manuel and Kim, Dong-Joo and Haubrich, Christina and others},
1733   - journal={PLoS medicine},
1734   - volume={14},
1735   - number={7},
1736   - pages={e1002348},
1737   - year={2017},
1738   - publisher={Public Library of Science San Francisco, CA USA}
  1554 + title = {Cerebrovascular pressure reactivity monitoring using wavelet analysis in traumatic brain injury patients: a retrospective study},
  1555 + author = {Liu, Xiuyun and Donnelly, Joseph and Czosnyka, Marek and Aries, Marcel JH and Brady, Ken and Cardim, Danilo and Robba, Chiara and Cabeleira, Manuel and Kim, Dong-Joo and Haubrich, Christina and others},
  1556 + year = 2017,
  1557 + journal = {PLoS medicine},
  1558 + publisher = {Public Library of Science San Francisco, CA USA},
  1559 + volume = 14,
  1560 + number = 7,
  1561 + pages = {e1002348}
1739 1562 }
1740   -
1741 1563 @article{lenell2024cerebrovascular,
1742   - title={Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury},
1743   - author={Lenell, Samuel and Wettervik, Teodor Svedung and Howells, Timothy and H{\aa}nell, Anders and Lew{\'e}n, Anders and Enblad, Per},
1744   - journal={Acta Neurochirurgica},
1745   - volume={166},
1746   - number={1},
1747   - pages={62},
1748   - year={2024},
1749   - publisher={Springer}
  1564 + title = {Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury},
  1565 + author = {Lenell, Samuel and Wettervik, Teodor Svedung and Howells, Timothy and H{\aa}nell, Anders and Lew{\'e}n, Anders and Enblad, Per},
  1566 + year = 2024,
  1567 + journal = {Acta Neurochirurgica},
  1568 + publisher = {Springer},
  1569 + volume = 166,
  1570 + number = 1,
  1571 + pages = 62
1750 1572 }
1751   -
1752 1573 @article{svedung2024should,
1753   - title={Should Patients with Traumatic Brain Injury with Significant Contusions be Treated with Different Neurointensive Care Targets?},
1754   - author={Svedung Wettervik, Teodor and H{\aa}nell, Anders and Lew{\'e}n, Anders and Enblad, Per},
1755   - journal={Neurocritical Care},
1756   - volume={41},
1757   - number={2},
1758   - pages={511--522},
1759   - year={2024},
1760   - publisher={Springer}
  1574 + title = {Should Patients with Traumatic Brain Injury with Significant Contusions be Treated with Different Neurointensive Care Targets?},
  1575 + author = {Svedung Wettervik, Teodor and H{\aa}nell, Anders and Lew{\'e}n, Anders and Enblad, Per},
  1576 + year = 2024,
  1577 + journal = {Neurocritical Care},
  1578 + publisher = {Springer},
  1579 + volume = 41,
  1580 + number = 2,
  1581 + pages = {511--522}
1761 1582 }
1762   -
1763 1583 @article{hong2024critical,
1764   - title={Critical thresholds of long-pressure reactivity index and impact of intracranial pressure monitoring methods in traumatic brain injury},
1765   - author={Hong, Erik and Froese, Logan and Pont{\'e}n, Emeli and Fletcher-Sandersj{\"o}{\"o}, Alexander and Tatter, Charles and Hammarlund, Emma and {\AA}kerlund, Cecilia AI and Tjerkaski, Jonathan and Alpkvist, Peter and Bartek Jr, Jiri and others},
1766   - journal={Critical Care},
1767   - volume={28},
1768   - number={1},
1769   - pages={256},
1770   - year={2024},
1771   - publisher={Springer}
  1584 + title = {Critical thresholds of long-pressure reactivity index and impact of intracranial pressure monitoring methods in traumatic brain injury},
  1585 + author = {Hong, Erik and Froese, Logan and Pont{\'e}n, Emeli and Fletcher-Sandersj{\"o}{\"o}, Alexander and Tatter, Charles and Hammarlund, Emma and {\AA}kerlund, Cecilia AI and Tjerkaski, Jonathan and Alpkvist, Peter and Bartek Jr, Jiri and others},
  1586 + year = 2024,
  1587 + journal = {Critical Care},
  1588 + publisher = {Springer},
  1589 + volume = 28,
  1590 + number = 1,
  1591 + pages = 256
1772 1592 }
1773   -
1774 1593 @article{riemann2020low,
1775   - title={Low-resolution pressure reactivity index and its derived optimal cerebral perfusion pressure in adult traumatic brain injury: a CENTER-TBI study},
1776   - author={Riemann, Lennart and Beqiri, Erta and Smielewski, Peter and Czosnyka, Marek and Stocchetti, Nino and Sakowitz, Oliver and Zweckberger, Klaus and Unterberg, Andreas and Younsi, Alexander},
1777   - journal={Critical care},
1778   - volume={24},
1779   - pages={1--12},
1780   - year={2020},
1781   - publisher={Springer}
  1594 + title = {Low-resolution pressure reactivity index and its derived optimal cerebral perfusion pressure in adult traumatic brain injury: a CENTER-TBI study},
  1595 + author = {Riemann, Lennart and Beqiri, Erta and Smielewski, Peter and Czosnyka, Marek and Stocchetti, Nino and Sakowitz, Oliver and Zweckberger, Klaus and Unterberg, Andreas and Younsi, Alexander},
  1596 + year = 2020,
  1597 + journal = {Critical care},
  1598 + publisher = {Springer},
  1599 + volume = 24,
  1600 + pages = {1--12}
1782 1601 }
1783   -
1784 1602 @article{zeiler2018validation,
1785   - title={Validation of intracranial pressure-derived cerebrovascular reactivity indices against the lower limit of autoregulation, part II: experimental model of arterial hypotension},
1786   - author={Zeiler, Frederick A and Lee, Jennifer K and Smielewski, Peter and Czosnyka, Marek and Brady, Ken},
1787   - journal={Journal of neurotrauma},
1788   - volume={35},
1789   - number={23},
1790   - pages={2812--2819},
1791   - year={2018},
1792   - publisher={Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…}
  1603 + title = {Validation of intracranial pressure-derived cerebrovascular reactivity indices against the lower limit of autoregulation, part II: experimental model of arterial hypotension},
  1604 + author = {Zeiler, Frederick A and Lee, Jennifer K and Smielewski, Peter and Czosnyka, Marek and Brady, Ken},
  1605 + year = 2018,
  1606 + journal = {Journal of neurotrauma},
  1607 + publisher = {Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New~…},
  1608 + volume = 35,
  1609 + number = 23,
  1610 + pages = {2812--2819}
1793 1611 }
1794   -
1795 1612 @article{hassett2023assessment,
1796   - title={Assessment of cerebral autoregulation using invasive and noninvasive methods of intracranial pressure monitoring},
1797   - author={Hassett, Catherine E and Uysal, S Pinar and Butler, Robert and Moore, Nina Z and Cardim, Danilo and Gomes, Joao A},
1798   - journal={Neurocritical Care},
1799   - volume={38},
1800   - number={3},
1801   - pages={591--599},
1802   - year={2023},
1803   - publisher={Springer}
  1613 + title = {Assessment of cerebral autoregulation using invasive and noninvasive methods of intracranial pressure monitoring},
  1614 + author = {Hassett, Catherine E and Uysal, S Pinar and Butler, Robert and Moore, Nina Z and Cardim, Danilo and Gomes, Joao A},
  1615 + year = 2023,
  1616 + journal = {Neurocritical Care},
  1617 + publisher = {Springer},
  1618 + volume = 38,
  1619 + number = 3,
  1620 + pages = {591--599}
1804 1621 }
1805   -
1806 1622 @article{ayasse2023cerebral,
1807   - title={Cerebral autoregulation: every step counts},
1808   - author={Ayasse, Timoth{\'e}e and Duranteau, Jacques and Harrois, Anatole and Pochard, Jonas},
1809   - journal={Critical Care},
1810   - volume={27},
1811   - number={1},
1812   - pages={311},
1813   - year={2023},
1814   - publisher={Springer}
  1623 + title = {Cerebral autoregulation: every step counts},
  1624 + author = {Ayasse, Timoth{\'e}e and Duranteau, Jacques and Harrois, Anatole and Pochard, Jonas},
  1625 + year = 2023,
  1626 + journal = {Critical Care},
  1627 + publisher = {Springer},
  1628 + volume = 27,
  1629 + number = 1,
  1630 + pages = 311
1815 1631 }
1816   -
1817 1632 @article{plourde2024variations,
1818   - title={Variations in autoregulation-based optimal cerebral perfusion pressure determination using two Integrated Neuromonitoring Platforms in a trauma patient},
1819   - author={Plourde, Guillaume and Carrier, François Martin and Bijlenga, Philippe and Quintard, Hervé},
1820   - journal={Neurocritical Care},
1821   - volume={41},
1822   - pages={386-392},
1823   - year={2024},
1824   - publisher={Springer},
  1633 + title = {Variations in autoregulation-based optimal cerebral perfusion pressure determination using two Integrated Neuromonitoring Platforms in a trauma patient},
  1634 + author = {Plourde, Guillaume and Carrier, François Martin and Bijlenga, Philippe and Quintard, Hervé},
  1635 + year = 2024,
  1636 + journal = {Neurocritical Care},
  1637 + publisher = {Springer},
  1638 + volume = 41,
  1639 + pages = {386--392}
1825 1640 }
1826   -
1827 1641 @article{kostoglou2024awhite,
1828   -author = {Kyriaki Kostoglou and Felipe Bello-Robles and Patrice Brassard and Max Chacon and Jurgen AHR Claassen and Marek Czosnyka and Jan-Willem Elting and Kun Hu and Lawrence Labrecque and Jia Liu and Vasilis Z Marmarelis and Stephen J Payne and Dae Cheol Shin and David Simpson and Jonathan Smirl and Ronney B Panerai and Georgios D Mitsis},
1829   -title ={Time-domain methods for quantifying dynamic cerebral blood flow autoregulation: Review and recommendations. A white paper from the Cerebrovascular Research Network (CARNet)},
1830   -journal = {Journal of Cerebral Blood Flow \& Metabolism},
1831   -volume = {44},
1832   -number = {9},
1833   -pages = {1480-1514},
1834   -year = {2024},
1835   -}
1836   -
  1642 + title = {Time-domain methods for quantifying dynamic cerebral blood flow autoregulation: Review and recommendations. A white paper from the Cerebrovascular Research Network (CARNet)},
  1643 + author = {Kyriaki Kostoglou and Felipe Bello-Robles and Patrice Brassard and Max Chacon and Jurgen AHR Claassen and Marek Czosnyka and Jan-Willem Elting and Kun Hu and Lawrence Labrecque and Jia Liu and Vasilis Z Marmarelis and Stephen J Payne and Dae Cheol Shin and David Simpson and Jonathan Smirl and Ronney B Panerai and Georgios D Mitsis},
  1644 + year = 2024,
  1645 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1646 + volume = 44,
  1647 + number = 9,
  1648 + pages = {1480--1514}
  1649 +}
1837 1650 @article{lo2008multimodal,
1838   - title={Multimodal pressure-flow analysis: Application of Hilbert Huang transform in cerebral blood flow regulation},
1839   - author={Lo, Men-Tzung and Hu, Kun and Liu, Yanhui and Peng, C-K and Novak, Vera},
1840   - journal={EURASIP journal on advances in signal processing},
1841   - volume={2008},
1842   - pages={1--15},
1843   - year={2008},
1844   - publisher={Springer}
  1651 + title = {Multimodal pressure-flow analysis: Application of Hilbert Huang transform in cerebral blood flow regulation},
  1652 + author = {Lo, Men-Tzung and Hu, Kun and Liu, Yanhui and Peng, C-K and Novak, Vera},
  1653 + year = 2008,
  1654 + journal = {EURASIP journal on advances in signal processing},
  1655 + publisher = {Springer},
  1656 + volume = 2008,
  1657 + pages = {1--15}
1845 1658 }
1846   -
1847 1659 @article{claassen2021regulation,
1848   - title={Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation},
1849   - author={Claassen, Jurgen AHR and Thijssen, Dick HJ and Panerai, Ronney B and Faraci, Frank M},
1850   - journal={Physiological reviews},
1851   - volume={101},
1852   - number={4},
1853   - pages={1487--1559},
1854   - year={2021},
1855   - publisher={American Physiological Society Rockville, MD}
  1660 + title = {Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation},
  1661 + author = {Claassen, Jurgen AHR and Thijssen, Dick HJ and Panerai, Ronney B and Faraci, Frank M},
  1662 + year = 2021,
  1663 + journal = {Physiological reviews},
  1664 + publisher = {American Physiological Society Rockville, MD},
  1665 + volume = 101,
  1666 + number = 4,
  1667 + pages = {1487--1559}
1856 1668 }
1857   -
1858 1669 @article{deimantavicius2022feasibility,
1859   - title={Feasibility of the optimal cerebral perfusion pressure value identification without a delay that is too long},
1860   - author={Deimantavicius, Mantas and Chaleckas, Edvinas and Boere, Katherine and Putnynaite, Vilma and Tamosuitis, Tomas and Tamasauskas, Arimantas and Kavaliauskas, Mindaugas and Rocka, Saulius and Preiksaitis, Aidanas and Vosylius, Saulius and others},
1861   - journal={Scientific Reports},
1862   - volume={12},
1863   - number={1},
1864   - pages={17724},
1865   - year={2022},
1866   - publisher={Nature Publishing Group UK London}
  1670 + title = {Feasibility of the optimal cerebral perfusion pressure value identification without a delay that is too long},
  1671 + author = {Deimantavicius, Mantas and Chaleckas, Edvinas and Boere, Katherine and Putnynaite, Vilma and Tamosuitis, Tomas and Tamasauskas, Arimantas and Kavaliauskas, Mindaugas and Rocka, Saulius and Preiksaitis, Aidanas and Vosylius, Saulius and others},
  1672 + year = 2022,
  1673 + journal = {Scientific Reports},
  1674 + publisher = {Nature Publishing Group UK London},
  1675 + volume = 12,
  1676 + number = 1,
  1677 + pages = 17724
1867 1678 }
1868   -
1869   -@article{olsen2022reliability,
1870   - title={Reliability of cerebral autoregulation using different measures of perfusion pressure in patients with subarachnoid hemorrhage},
1871   - author={Olsen, Markus Harboe and Capion, Tenna and Riberholt, Christian Gunge and Bache, S{\o}ren and Berg, Ronan MG and M{\o}ller, Kirsten},
1872   - journal={Physiological Reports},
1873   - volume={10},
1874   - number={6},
1875   - pages={e15203},
1876   - year={2022},
1877   - publisher={Wiley Online Library}
1878   -}
1879   -
1880 1679 @article{heutz2023dynamic,
1881   - title={Dynamic cerebral autoregulation in Alzheimer’s disease and mild cognitive impairment: A systematic review},
1882   - author={Heutz, Rachel and Claassen, Jurgen and Feiner, Sanne and Davies, Aaron and Gurung, Dewakar and Panerai, Ronney B and Heus, Rianne de and Beishon, Lucy C},
1883   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1884   - volume={43},
1885   - number={8},
1886   - pages={1223--1236},
1887   - year={2023},
1888   - publisher={SAGE Publications Sage UK: London, England}
  1680 + title = {Dynamic cerebral autoregulation in Alzheimer’s disease and mild cognitive impairment: A systematic review},
  1681 + author = {Heutz, Rachel and Claassen, Jurgen and Feiner, Sanne and Davies, Aaron and Gurung, Dewakar and Panerai, Ronney B and Heus, Rianne de and Beishon, Lucy C},
  1682 + year = 2023,
  1683 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1684 + publisher = {SAGE Publications Sage UK: London, England},
  1685 + volume = 43,
  1686 + number = 8,
  1687 + pages = {1223--1236}
1889 1688 }
1890   -
1891   -@article{panerai2023transfer,
1892   - title={Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update},
1893   - author={Panerai, Ronney B and Brassard, Patrice and Burma, Joel S and Castro, Pedro and Claassen, Jurgen AHR and van Lieshout, Johannes J and Liu, Jia and Lucas, Samuel JE and Minhas, Jatinder S and Mitsis, Georgios D and others},
1894   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1895   - volume={43},
1896   - number={1},
1897   - pages={3--25},
1898   - year={2023},
1899   - publisher={SAGE Publications Sage UK: London, England}
1900   -}
1901   -
1902   -@article{panerai2023transfer,
1903   - title={Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update},
1904   - author={Panerai, Ronney B and Brassard, Patrice and Burma, Joel S and Castro, Pedro and Claassen, Jurgen AHR and van Lieshout, Johannes J and Liu, Jia and Lucas, Samuel JE and Minhas, Jatinder S and Mitsis, Georgios D and others},
1905   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1906   - volume={43},
1907   - number={1},
1908   - pages={3--25},
1909   - year={2023},
1910   - publisher={SAGE Publications Sage UK: London, England}
1911   -}
1912   -
1913 1689 @article{liu2015comparison,
1914   - title={Comparison of frequency and time domain methods of assessment of cerebral autoregulation in traumatic brain injury},
1915   - author={Liu, Xiuyun and Czosnyka, Marek and Donnelly, Joseph and Budohoski, Karol P and Varsos, Georgios V and Nasr, Nathalie and Brady, Ken M and Reinhard, Matthias and Hutchinson, Peter J and Smielewski, Peter},
1916   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1917   - volume={35},
1918   - number={2},
1919   - pages={248--256},
1920   - year={2015},
1921   - publisher={SAGE Publications Sage UK: London, England}
  1690 + title = {Comparison of frequency and time domain methods of assessment of cerebral autoregulation in traumatic brain injury},
  1691 + author = {Liu, Xiuyun and Czosnyka, Marek and Donnelly, Joseph and Budohoski, Karol P and Varsos, Georgios V and Nasr, Nathalie and Brady, Ken M and Reinhard, Matthias and Hutchinson, Peter J and Smielewski, Peter},
  1692 + year = 2015,
  1693 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1694 + publisher = {SAGE Publications Sage UK: London, England},
  1695 + volume = 35,
  1696 + number = 2,
  1697 + pages = {248--256}
1922 1698 }
1923   -
1924 1699 %%% ref EC2%%%
1925 1700 @article{kazimierska2021compliance,
1926   - title={Compliance of the cerebrospinal space: comparison of three methods},
1927   - author={Kazimierska, Agnieszka and Kasprowicz, Magdalena and Czosnyka, Marek and Placek, Micha{\l} M and Baledent, Olivier and Smielewski, Peter and Czosnyka, Zofia},
1928   - journal={Acta neurochirurgica},
1929   - volume={163},
1930   - pages={1979--1989},
1931   - year={2021},
1932   - publisher={Springer}
  1701 + title = {Compliance of the cerebrospinal space: comparison of three methods},
  1702 + author = {Kazimierska, Agnieszka and Kasprowicz, Magdalena and Czosnyka, Marek and Placek, Micha{\l} M and Baledent, Olivier and Smielewski, Peter and Czosnyka, Zofia},
  1703 + year = 2021,
  1704 + journal = {Acta neurochirurgica},
  1705 + publisher = {Springer},
  1706 + volume = 163,
  1707 + pages = {1979--1989}
1933 1708 }
1934   -
1935 1709 @article{intharakham2019assessment,
1936   - title={Assessment of cerebral autoregulation in stroke: a systematic review and meta-analysis of studies at rest},
1937   - author={Intharakham, Kannakorn and Beishon, Lucy and Panerai, Ronney B and Haunton, Victoria J and Robinson, Thompson G},
1938   - journal={Journal of Cerebral Blood Flow \& Metabolism},
1939   - volume={39},
1940   - number={11},
1941   - pages={2105--2116},
1942   - year={2019},
1943   - publisher={SAGE Publications Sage UK: London, England}
  1710 + title = {Assessment of cerebral autoregulation in stroke: a systematic review and meta-analysis of studies at rest},
  1711 + author = {Intharakham, Kannakorn and Beishon, Lucy and Panerai, Ronney B and Haunton, Victoria J and Robinson, Thompson G},
  1712 + year = 2019,
  1713 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1714 + publisher = {SAGE Publications Sage UK: London, England},
  1715 + volume = 39,
  1716 + number = 11,
  1717 + pages = {2105--2116}
1944 1718 }
1945   -
1946 1719 @article{vitt2023multimodal,
1947   - title={Multimodal and autoregulation monitoring in the neurointensive care unit},
1948   - author={Vitt, Jeffrey R and Loper, Nicholas E and Mainali, Shraddha},
1949   - journal={Frontiers in neurology},
1950   - volume={14},
1951   - pages={1155986},
1952   - year={2023},
1953   - publisher={Frontiers Media SA}
  1720 + title = {Multimodal and autoregulation monitoring in the neurointensive care unit},
  1721 + author = {Vitt, Jeffrey R and Loper, Nicholas E and Mainali, Shraddha},
  1722 + year = 2023,
  1723 + journal = {Frontiers in neurology},
  1724 + publisher = {Frontiers Media SA},
  1725 + volume = 14,
  1726 + pages = 1155986
1954 1727 }
1955   -
1956 1728 @article{eide2007association,
1957   - title={Association among intracranial compliance, intracranial pulse pressure amplitude and intracranial pressure in patients with intracranial bleeds},
1958   - author={Eide, PK and Sorteberg, W},
1959   - journal={Neurological research},
1960   - volume={29},
1961   - number={8},
1962   - pages={798--802},
1963   - year={2007},
1964   - publisher={Taylor \& Francis}
  1729 + title = {Association among intracranial compliance, intracranial pulse pressure amplitude and intracranial pressure in patients with intracranial bleeds},
  1730 + author = {Eide, PK and Sorteberg, W},
  1731 + year = 2007,
  1732 + journal = {Neurological research},
  1733 + publisher = {Taylor \& Francis},
  1734 + volume = 29,
  1735 + number = 8,
  1736 + pages = {798--802}
1965 1737 }
1966   -
1967 1738 @article{magnaes1976body,
1968   - title={Body position and cerebrospinal fluid pressure: Part 1: Clinical studies on the effect of rapid postural changes},
1969   - author={Magn{\ae}s, Bj{\o}rn},
1970   - journal={Journal of neurosurgery},
1971   - volume={44},
1972   - number={6},
1973   - pages={687--697},
1974   - year={1976},
1975   - publisher={Journal of Neurosurgery Publishing Group}
  1739 + title = {Body position and cerebrospinal fluid pressure: Part 1: Clinical studies on the effect of rapid postural changes},
  1740 + author = {Magn{\ae}s, Bj{\o}rn},
  1741 + year = 1976,
  1742 + journal = {Journal of neurosurgery},
  1743 + publisher = {Journal of Neurosurgery Publishing Group},
  1744 + volume = 44,
  1745 + number = 6,
  1746 + pages = {687--697}
1976 1747 }
1977   -
1978 1748 @article{gergele2021postural,
1979   - title={Postural regulation of intracranial pressure: a critical review of the literature},
1980   - author={Gergel{\'e}, Laurent and Manet, Romain},
1981   - journal={Intracranial Pressure and Neuromonitoring XVII},
1982   - pages={339--342},
1983   - year={2021},
1984   - publisher={Springer}
  1749 + title = {Postural regulation of intracranial pressure: a critical review of the literature},
  1750 + author = {Gergel{\'e}, Laurent and Manet, Romain},
  1751 + year = 2021,
  1752 + journal = {Intracranial Pressure and Neuromonitoring XVII},
  1753 + publisher = {Springer},
  1754 + pages = {339--342}
1985 1755 }
1986   -
1987 1756 @article{koster2012snakemake,
1988   - title={Snakemake—a scalable bioinformatics workflow engine},
1989   - author={K{\"o}ster, Johannes and Rahmann, Sven},
1990   - journal={Bioinformatics},
1991   - volume={28},
1992   - number={19},
1993   - pages={2520--2522},
1994   - year={2012},
1995   - publisher={Oxford University Press}
  1757 + title = {Snakemake—a scalable bioinformatics workflow engine},
  1758 + author = {K{\"o}ster, Johannes and Rahmann, Sven},
  1759 + year = 2012,
  1760 + journal = {Bioinformatics},
  1761 + publisher = {Oxford University Press},
  1762 + volume = 28,
  1763 + number = 19,
  1764 + pages = {2520--2522}
1996 1765 }
1997   -
1998 1766 @article{tiwari2021analysis,
1999   - title={Analysis of heart rate variability and implication of different factors on heart rate variability},
2000   - author={Tiwari, Reena and Kumar, Ravindra and Malik, Sujata and Raj, Tilak and Kumar, Punit},
2001   - journal={Current cardiology reviews},
2002   - volume={17},
2003   - number={5},
2004   - year={2021},
2005   - publisher={Bentham Science Publishers}
  1767 + title = {Analysis of heart rate variability and implication of different factors on heart rate variability},
  1768 + author = {Tiwari, Reena and Kumar, Ravindra and Malik, Sujata and Raj, Tilak and Kumar, Punit},
  1769 + year = 2021,
  1770 + journal = {Current cardiology reviews},
  1771 + publisher = {Bentham Science Publishers},
  1772 + volume = 17,
  1773 + number = 5
2006 1774 }
2007   -
2008 1775 @article{pose2023permutation,
2009   - title={Permutation Entropy Analysis to Intracranial Hypertension from a Porcine Model},
2010   - author={Pose, Fernando and Ciarrocchi, Nicolas and Videla, Carlos and Redelico, Francisco O},
2011   - journal={Entropy},
2012   - volume={25},
2013   - number={2},
2014   - pages={267},
2015   - year={2023},
2016   - publisher={MDPI}
  1776 + title = {Permutation Entropy Analysis to Intracranial Hypertension from a Porcine Model},
  1777 + author = {Pose, Fernando and Ciarrocchi, Nicolas and Videla, Carlos and Redelico, Francisco O},
  1778 + year = 2023,
  1779 + journal = {Entropy},
  1780 + publisher = {MDPI},
  1781 + volume = 25,
  1782 + number = 2,
  1783 + pages = 267
2017 1784 }
2018   -
2019 1785 @article{pessa2021ordpy,
2020   - title={ordpy: A Python package for data analysis with permutation entropy and ordinal network methods},
2021   - author={Pessa, Arthur AB and Ribeiro, Haroldo V},
2022   - journal={Chaos: An Interdisciplinary Journal of Nonlinear Science},
2023   - volume={31},
2024   - number={6},
2025   - year={2021},
2026   - publisher={AIP Publishing}
  1786 + title = {ordpy: A Python package for data analysis with permutation entropy and ordinal network methods},
  1787 + author = {Pessa, Arthur AB and Ribeiro, Haroldo V},
  1788 + year = 2021,
  1789 + journal = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  1790 + publisher = {AIP Publishing},
  1791 + volume = 31,
  1792 + number = 6
2027 1793 }
2028   -
2029 1794 @inproceedings{bach2008bolasso,
2030   - title={Bolasso: model consistent lasso estimation through the bootstrap},
2031   - author={Bach, Francis R},
2032   - booktitle={Proceedings of the 25th international conference on Machine learning},
2033   - pages={33--40},
2034   - year={2008}
  1795 + title = {Bolasso: model consistent lasso estimation through the bootstrap},
  1796 + author = {Bach, Francis R},
  1797 + year = 2008,
  1798 + booktitle = {Proceedings of the 25th international conference on Machine learning},
  1799 + pages = {33--40}
2035 1800 }
2036   -
2037 1801 @article{pedregosa2011scikit,
2038   - title={Scikit-learn: Machine learning in Python},
2039   - author={Pedregosa, Fabian and Varoquaux, Ga{\"e}l and Gramfort, Alexandre and Michel, Vincent and Thirion, Bertrand and Grisel, Olivier and Blondel, Mathieu and Prettenhofer, Peter and Weiss, Ron and Dubourg, Vincent and others},
2040   - journal={the Journal of machine Learning research},
2041   - volume={12},
2042   - pages={2825--2830},
2043   - year={2011},
2044   - publisher={JMLR. org}
  1802 + title = {Scikit-learn: Machine learning in Python},
  1803 + author = {Pedregosa, Fabian and Varoquaux, Ga{\"e}l and Gramfort, Alexandre and Michel, Vincent and Thirion, Bertrand and Grisel, Olivier and Blondel, Mathieu and Prettenhofer, Peter and Weiss, Ron and Dubourg, Vincent and others},
  1804 + year = 2011,
  1805 + journal = {the Journal of machine Learning research},
  1806 + publisher = {JMLR. org},
  1807 + volume = 12,
  1808 + pages = {2825--2830}
2045 1809 }
2046   -
2047 1810 @article{alperin2005quantifying,
2048   - title={Quantifying the effect of posture on intracranial physiology in humans by MRI flow studies},
2049   - author={Alperin, Noam and Lee, Sang H and Sivaramakrishnan, Anusha and Hushek, Stephen G},
2050   - journal={Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine},
2051   - volume={22},
2052   - number={5},
2053   - pages={591--596},
2054   - year={2005},
2055   - publisher={Wiley Online Library}
  1811 + title = {Quantifying the effect of posture on intracranial physiology in humans by MRI flow studies},
  1812 + author = {Alperin, Noam and Lee, Sang H and Sivaramakrishnan, Anusha and Hushek, Stephen G},
  1813 + year = 2005,
  1814 + journal = {Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine},
  1815 + publisher = {Wiley Online Library},
  1816 + volume = 22,
  1817 + number = 5,
  1818 + pages = {591--596}
2056 1819 }
2057   -
2058 1820 @article{czosnyka1996significance,
2059   - title={Significance of intracranial pressure waveform analysis after head injury},
2060   - author={Czosnyka, M and Guazzo, E and Whitehouse, M and Smielewski, P and Czosnyka, Z and Kirkpatrick, P and Piechnik, S and Pickard, JD},
2061   - journal={Acta neurochirurgica},
2062   - volume={138},
2063   - pages={531--542},
2064   - year={1996},
2065   - publisher={Springer}
2066   -}
2067   -
  1821 + title = {Significance of intracranial pressure waveform analysis after head injury},
  1822 + author = {Czosnyka, M and Guazzo, E and Whitehouse, M and Smielewski, P and Czosnyka, Z and Kirkpatrick, P and Piechnik, S and Pickard, JD},
  1823 + year = 1996,
  1824 + journal = {Acta neurochirurgica},
  1825 + publisher = {Springer},
  1826 + volume = 138,
  1827 + pages = {531--542}
  1828 +}
2068 1829 @article{norager2020changes,
2069   - title={Changes in intracranial pressure and pulse wave amplitude during postural shifts},
2070   - author={Norager, Nicolas Hernandez and Olsen, Markus Harboe and Riedel, Casper Schwartz and Juhler, Marianne},
2071   - journal={Acta Neurochirurgica},
2072   - volume={162},
2073   - pages={2983--2989},
2074   - year={2020},
2075   - publisher={Springer}
  1830 + title = {Changes in intracranial pressure and pulse wave amplitude during postural shifts},
  1831 + author = {Norager, Nicolas Hernandez and Olsen, Markus Harboe and Riedel, Casper Schwartz and Juhler, Marianne},
  1832 + year = 2020,
  1833 + journal = {Acta Neurochirurgica},
  1834 + publisher = {Springer},
  1835 + volume = 162,
  1836 + pages = {2983--2989}
2076 1837 }
2077   -
2078 1838 @article{schneider1993influence,
2079   - title={Influence of body position on jugular venous oxygen saturation, intracranial pressure and cerebral perfusion pressure},
2080   - author={Schneider, G-H and v Helden, A and Franke, R and Lanksch, WR and Unterberg, A},
2081   - journal={Monitoring of Cerebral Blood Flow and Metabolism in Intensive Care},
2082   - pages={107--112},
2083   - year={1993},
2084   - publisher={Springer}
  1839 + title = {Influence of body position on jugular venous oxygen saturation, intracranial pressure and cerebral perfusion pressure},
  1840 + author = {Schneider, G-H and v Helden, A and Franke, R and Lanksch, WR and Unterberg, A},
  1841 + year = 1993,
  1842 + journal = {Monitoring of Cerebral Blood Flow and Metabolism in Intensive Care},
  1843 + publisher = {Springer},
  1844 + pages = {107--112}
2085 1845 }
2086 1846 @article{fan2004effect,
2087   - title={Effect of backrest position on intracranial pressure and cerebral perfusion pressure in individuals with brain injury: a systematic review},
2088   - author={Fan, Jun-Yu},
2089   - journal={Journal of Neuroscience Nursing},
2090   - volume={36},
2091   - number={5},
2092   - pages={278--288},
2093   - year={2004},
2094   - publisher={LWW}
  1847 + title = {Effect of backrest position on intracranial pressure and cerebral perfusion pressure in individuals with brain injury: a systematic review},
  1848 + author = {Fan, Jun-Yu},
  1849 + year = 2004,
  1850 + journal = {Journal of Neuroscience Nursing},
  1851 + publisher = {LWW},
  1852 + volume = 36,
  1853 + number = 5,
  1854 + pages = {278--288}
2095 1855 }
2096   -
2097 1856 @article{schmid1999changes,
2098   - title={Changes in cross-sectional measurements of the spinal canal and intervertebral foramina as a function of body position: in vivo studies on an open-configuration MR system.},
2099   - author={Schmid, Marius R and Stucki, Gerold and Duewell, S and Wildermuth, S and Romanowski, B and Hodler, J},
2100   - journal={AJR. American journal of roentgenology},
2101   - volume={172},
2102   - number={4},
2103   - pages={1095--1102},
2104   - year={1999},
2105   - publisher={Am Roentgen Ray Soc}
  1857 + title = {Changes in cross-sectional measurements of the spinal canal and intervertebral foramina as a function of body position: in vivo studies on an open-configuration MR system.},
  1858 + author = {Schmid, Marius R and Stucki, Gerold and Duewell, S and Wildermuth, S and Romanowski, B and Hodler, J},
  1859 + year = 1999,
  1860 + journal = {AJR. American journal of roentgenology},
  1861 + publisher = {Am Roentgen Ray Soc},
  1862 + volume = 172,
  1863 + number = 4,
  1864 + pages = {1095--1102}
2106 1865 }
2107   -
2108 1866 @article{d2021effect,
2109   - title={Effect of position on intracranial pressure and compliance: a cross-sectional study including 101 patients},
2110   - author={D’Antona, Linda and Craven, Claudia Louise and Bremner, Fion and Matharu, Manjit Singh and Thorne, Lewis and Watkins, Laurence Dale and Toma, Ahmed Kassem},
2111   - journal={Journal of Neurosurgery},
2112   - volume={136},
2113   - number={6},
2114   - pages={1781--1789},
2115   - year={2021},
2116   - publisher={American Association of Neurological Surgeons}
  1867 + title = {Effect of position on intracranial pressure and compliance: a cross-sectional study including 101 patients},
  1868 + author = {D’Antona, Linda and Craven, Claudia Louise and Bremner, Fion and Matharu, Manjit Singh and Thorne, Lewis and Watkins, Laurence Dale and Toma, Ahmed Kassem},
  1869 + year = 2021,
  1870 + journal = {Journal of Neurosurgery},
  1871 + publisher = {American Association of Neurological Surgeons},
  1872 + volume = 136,
  1873 + number = 6,
  1874 + pages = {1781--1789}
2117 1875 }
2118   -
2119 1876 @article{czosnyka2001age,
2120   - title={Age dependence of cerebrospinal pressure—volume compensation in patients with hydrocephalus},
2121   - author={Czosnyka, Marek and Czosnyka, Zofia H and Whitfield, Peter C and Donovan, Tim and Pickard, John D},
2122   - journal={Journal of neurosurgery},
2123   - volume={94},
2124   - number={3},
2125   - pages={482--486},
2126   - year={2001},
2127   - publisher={Journal of Neurosurgery Publishing Group}
  1877 + title = {Age dependence of cerebrospinal pressure—volume compensation in patients with hydrocephalus},
  1878 + author = {Czosnyka, Marek and Czosnyka, Zofia H and Whitfield, Peter C and Donovan, Tim and Pickard, John D},
  1879 + year = 2001,
  1880 + journal = {Journal of neurosurgery},
  1881 + publisher = {Journal of Neurosurgery Publishing Group},
  1882 + volume = 94,
  1883 + number = 3,
  1884 + pages = {482--486}
2128 1885 }
2129   -
2130 1886 @article{tans1989relationship,
2131   - title={Relationship between compliance and resistance to outflow of CSF in adult hydrocephalus},
2132   - author={Tans, Joseph TJ and Poortvliet, Dick CJ},
2133   - journal={Journal of neurosurgery},
2134   - volume={71},
2135   - number={1},
2136   - pages={59--62},
2137   - year={1989},
2138   - publisher={Journal of Neurosurgery Publishing Group}
  1887 + title = {Relationship between compliance and resistance to outflow of CSF in adult hydrocephalus},
  1888 + author = {Tans, Joseph TJ and Poortvliet, Dick CJ},
  1889 + year = 1989,
  1890 + journal = {Journal of neurosurgery},
  1891 + publisher = {Journal of Neurosurgery Publishing Group},
  1892 + volume = 71,
  1893 + number = 1,
  1894 + pages = {59--62}
2139 1895 }
2140   -
2141 1896 @inproceedings{kiening2005assessment,
2142   - title={Assessment of the relationship between age and continuous intracranial compliance},
2143   - author={Kiening, KL and Schoening, W and Unterberg, AW and Stover, JF and Citerio, G and Enblad, Per and Nilsson, Pelle and Brain-IT Group},
2144   - booktitle={Intracranial Pressure and Brain Monitoring XII},
2145   - pages={293--297},
2146   - year={2005},
2147   - organization={Springer}
  1897 + title = {Assessment of the relationship between age and continuous intracranial compliance},
  1898 + author = {Kiening, KL and Schoening, W and Unterberg, AW and Stover, JF and Citerio, G and Enblad, Per and Nilsson, Pelle and Brain-IT Group},
  1899 + year = 2005,
  1900 + booktitle = {Intracranial Pressure and Brain Monitoring XII},
  1901 + pages = {293--297},
  1902 + organization = {Springer}
2148 1903 }
2149   -
2150 1904 @article{zarrinkoob2016aging,
2151   - title={Aging alters the dampening of pulsatile blood flow in cerebral arteries},
2152   - author={Zarrinkoob, Laleh and Ambarki, Khalid and W{\aa}hlin, Anders and Birgander, Richard and Carlberg, Bo and Eklund, Anders and Malm, Jan},
2153   - journal={Journal of Cerebral Blood Flow \& Metabolism},
2154   - volume={36},
2155   - number={9},
2156   - pages={1519--1527},
2157   - year={2016},
2158   - publisher={SAGE Publications Sage UK: London, England}
  1905 + title = {Aging alters the dampening of pulsatile blood flow in cerebral arteries},
  1906 + author = {Zarrinkoob, Laleh and Ambarki, Khalid and W{\aa}hlin, Anders and Birgander, Richard and Carlberg, Bo and Eklund, Anders and Malm, Jan},
  1907 + year = 2016,
  1908 + journal = {Journal of Cerebral Blood Flow \& Metabolism},
  1909 + publisher = {SAGE Publications Sage UK: London, England},
  1910 + volume = 36,
  1911 + number = 9,
  1912 + pages = {1519--1527}
2159 1913 }
2160   -
2161 1914 @article{hayashi1980stiffness,
2162   - title={Stiffness and elastic behavior of human intracranial and extracranial arteries},
2163   - author={Hayashi, K and Handa, H and Nagasawa, S and Okumura, A and Moritake, K},
2164   - journal={Journal of biomechanics},
2165   - volume={13},
2166   - number={2},
2167   - pages={175--184},
2168   - year={1980},
2169   - publisher={Elsevier}
  1915 + title = {Stiffness and elastic behavior of human intracranial and extracranial arteries},
  1916 + author = {Hayashi, K and Handa, H and Nagasawa, S and Okumura, A and Moritake, K},
  1917 + year = 1980,
  1918 + journal = {Journal of biomechanics},
  1919 + publisher = {Elsevier},
  1920 + volume = 13,
  1921 + number = 2,
  1922 + pages = {175--184}
2170 1923 }
2171   -
2172   -
2173 1924 @article{brasil2021intracranial,
2174   - title={Intracranial compliance assessed by intracranial pressure pulse waveform},
2175   - author={Brasil, S{\'e}rgio and Solla, Davi Jorge Fontoura and Nogueira, Ricardo de Carvalho and Jacobsen Teixeira, Manoel and Malbouisson, Luiz Marcelo S{\'a} and Paiva, Wellingson Silva},
2176   - journal={Brain Sciences},
2177   - volume={11},
2178   - number={8},
2179   - pages={971},
2180   - year={2021},
2181   - publisher={Multidisciplinary Digital Publishing Institute}
  1925 + title = {Intracranial compliance assessed by intracranial pressure pulse waveform},
  1926 + author = {Brasil, S{\'e}rgio and Solla, Davi Jorge Fontoura and Nogueira, Ricardo de Carvalho and Jacobsen Teixeira, Manoel and Malbouisson, Luiz Marcelo S{\'a} and Paiva, Wellingson Silva},
  1927 + year = 2021,
  1928 + journal = {Brain Sciences},
  1929 + publisher = {Multidisciplinary Digital Publishing Institute},
  1930 + volume = 11,
  1931 + number = 8,
  1932 + pages = 971
2182 1933 }
2183   -
2184 1934 @article{dias2014post,
2185   - title={Post-traumatic multimodal brain monitoring: response to hypertonic saline},
2186   - author={Dias, Celeste and Silva, Maria Joao and Pereira, Eduarda and Silva, Sofia and Cerejo, Ant{\'o}nio and Smielewski, Peter and Rocha, Ana Paula and Gaio, A Rita and Paiva, Jos{\'e}-Artur and Czosnyka, Marek},
2187   - journal={Journal of neurotrauma},
2188   - volume={31},
2189   - number={22},
2190   - pages={1872--1880},
2191   - year={2014},
2192   - publisher={Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA}
  1935 + title = {Post-traumatic multimodal brain monitoring: response to hypertonic saline},
  1936 + author = {Dias, Celeste and Silva, Maria Joao and Pereira, Eduarda and Silva, Sofia and Cerejo, Ant{\'o}nio and Smielewski, Peter and Rocha, Ana Paula and Gaio, A Rita and Paiva, Jos{\'e}-Artur and Czosnyka, Marek},
  1937 + year = 2014,
  1938 + journal = {Journal of neurotrauma},
  1939 + publisher = {Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA},
  1940 + volume = 31,
  1941 + number = 22,
  1942 + pages = {1872--1880}
2193 1943 }
2194   -
2195 1944 @article{khasiyev2024safety,
2196   - title={Safety and Effect on Intracranial pressure of 3\% hypertonic saline Bolus Via Peripheral Intravenous catheter for neurological emergencies},
2197   - author={Khasiyev, Farid and Hakoun, Abdullah and Christopher, Kara and Braun, James and Wang, Fajun},
2198   - journal={Neurocritical Care},
2199   - volume={41},
  1945 + title = {Safety and Effect on Intracranial pressure of 3\% hypertonic saline Bolus Via Peripheral Intravenous catheter for neurological emergencies},
  1946 + author = {Khasiyev, Farid and Hakoun, Abdullah and Christopher, Kara and Braun, James and Wang, Fajun},
  1947 + year = 2024,
  1948 + journal = {Neurocritical Care},
  1949 + publisher = {Springer},
  1950 + volume = 41,
  1951 + number = 1,
  1952 + pages = {202--207}
  1953 +}
  1954 +@article{park2024should,
  1955 + title = {Should Hypertonic Saline Be Considered for the Treatment of Intracranial Hypertension? A Review of Current Evidence and Clinical Practices},
  1956 + author = {Park, Moowan and Shim, Youngbo and Choo, Yoon-Hee and Kim, Hye Seon and Kim, Jungook and Ha, Eun Jin},
  1957 + year = 2024,
  1958 + journal = {Korean journal of neurotrauma},
  1959 + volume = 20,
  1960 + number = 3,
  1961 + pages = 146
  1962 +}
  1963 +@article{suasti2021regulation,
  1964 + title = {Regulation and Intervention of Intracranial Pressure},
  1965 + author = {Suasti, Ni Wayan Lisa},
  1966 + year = 2021,
  1967 + journal = {Bioscientia Medicina: Journal of Biomedicine and Translational Research},
  1968 + publisher = {HM Publisher},
  1969 + volume = 5,
  1970 + number = 10,
  1971 + pages = {981--987}
  1972 +}
  1973 +
  1974 +@article{bakdash2017repeated,
  1975 + title={Repeated measures correlation},
  1976 + author={Bakdash, Jonathan Z and Marusich, Laura R},
  1977 + journal={Frontiers in psychology},
  1978 + volume={8},
  1979 + pages={456},
  1980 + year={2017},
  1981 + publisher={Frontiers Media SA}
  1982 +}
  1983 +
  1984 +@article{kasprowicz2025impact,
  1985 + title={Impact of age and mean intracranial pressure on the morphology of intracranial pressure waveform and its association with mortality in traumatic brain injury},
  1986 + author={Kasprowicz, Magdalena and Mataczy{\'n}ski, Cyprian and Uryga, Agnieszka and Pelah, Adam I and Schmidt, Eric and Czosnyka, Marek and Kazimierska, Agnieszka},
  1987 + journal={Critical Care},
  1988 + volume={29},
2200 1989 number={1},
2201   - pages={202--207},
2202   - year={2024},
  1990 + pages={1--12},
  1991 + year={2025},
2203 1992 publisher={Springer}
2204 1993 }
2205 1994  
2206   -@article{park2024should,
2207   - title={Should Hypertonic Saline Be Considered for the Treatment of Intracranial Hypertension? A Review of Current Evidence and Clinical Practices},
2208   - author={Park, Moowan and Shim, Youngbo and Choo, Yoon-Hee and Kim, Hye Seon and Kim, Jungook and Ha, Eun Jin},
2209   - journal={Korean journal of neurotrauma},
2210   - volume={20},
2211   - number={3},
2212   - pages={146},
2213   - year={2024}
2214   -}
2215 1995  
2216   -@article{suasti2021regulation,
2217   - title={Regulation and Intervention of Intracranial Pressure},
2218   - author={Suasti, Ni Wayan Lisa},
2219   - journal={Bioscientia Medicina: Journal of Biomedicine and Translational Research},
2220   - volume={5},
2221   - number={10},
2222   - pages={981--987},
2223   - year={2021},
2224   - publisher={HM Publisher}
  1996 +@article{ballestero2023can,
  1997 + title={Can a new noninvasive method for assessment of intracranial pressure predict intracranial hypertension and prognosis?},
  1998 + author={Ballestero, Matheus and Dias, Celeste and Gomes, In{\^e}s Catarina Neves and Grisi, Luca Soares and Cardoso, Rodrigo Augusto Monteiro and J{\'u}nior, Edson Luis Zucoloto and de Oliveira, Ricardo Santos},
  1999 + journal={Acta Neurochirurgica},
  2000 + volume={165},
  2001 + number={6},
  2002 + pages={1495--1503},
  2003 + year={2023},
  2004 + publisher={Springer}
2225 2005 }
chapters/HTS.tex View file @ 06e210b
1   -Ce chapitre constitue une ré-analyse de l'étude rétrospective menée par Dias \textit{et al.}~\cite{dias2014post} portant sur l'injection solution saline hypertonique (SSH) pour le traitement de l'hypertension intracrânienne (HTIC) de patients atteints de traumatisme crânien(TC). L'objectif est d'approfondir les recherches effectuées en se concentrant sur les changements dans la morphologie du signal de PIC, et ainsi d'étudier la relation entre injection de SSH et compliance cérébrale.
  1 +Ce chapitre constitue une ré-analyse de l'étude rétrospective menée par Dias \textit{et al.}~\cite{dias2014post} portant sur l'injection solution saline hypertonique (SSH) pour le traitement de l'hypertension intracrânienne (HTIC) de patients atteints de traumatisme crânien (TC). L'objectif est d'approfondir les recherches effectuées en se concentrant sur les changements dans la morphologie du signal de PIC, et ainsi d'étudier les effets de l'injection de SSH sur la compliance cérébrale du patient.
2 2  
3 3 \section{Introduction}
4   -Les thérapies à base de solutions hyper-osmolaires font partie des solutions cliniques de routine pour le traitement d'hypertension intracrânienne. Les solutions utilisées contiennent généralement du mannitol ou du NaCl en concentration variable, de 1.8\% à 23.4\%~\cite{khasiyev2024safety}. Si ce dernier traitement ne comporte que peu de risques et permet effectivement une baisse passagère de la PIC~\cite{khasiyev2024safety}, aucune association n'a pu être établie avec le devenir neurologique à long terme des patients traités~\cite{bernhardt2024hypertonic}. Les mécanismes d'actions sont pas complètement identifiés, et ne peuvent être résumés au drainage osmotique du liquide interstitiel cérébral dans la circulation sanguine~\cite{park2024should}. L'injection de SSH provoque également une augmentation de volume sanguin induisant un déplacement d'eau de l'intérieur vers l'extérieur de la membrane des globules rouges. Le débit sanguin cérébral est alors augmenté par la conjonction de trois effets : hémodilution, augmentation du diamètre de la lumière endothéliale et diminution du diamètre des globules rouges (). Les mécanismes d'autorégulation cérébrale sont alors mis en jeu et causent une vasoconstriction réflexe, menant finalement à une baisse du volume sanguin cérébral et donc de la PIC (). Ces effets ne sont cependant par immédiats ; il faut compter 20 à 30 minutes après l'injection de SSH avant la formation du gradient osmotique~\cite{park2024should}. Cette modification induite du volume sanguin cérébral constitue donc un contexte utile à l'étude de la compliance cérébrale des patients traités par injection de SSH. L'objectif de la ré-analyse est d'étudier les changements dans la morphologie des pulsations cardiaques sur le signal de PIC lors de l'augmentation des réserves de compliance cérébrale induite par l'injection de SSH.
  4 +Les thérapies à base de solutions hyper-osmolaires font partie des solutions cliniques de routine pour le traitement d'hypertension intracrânienne. Les solutions utilisées contiennent généralement du mannitol ou du NaCl en concentration variable, de 1.8\% à 23.4\%~\cite{khasiyev2024safety}. Si ce dernier traitement ne comporte que peu de risques et permet effectivement une baisse passagère de la PIC~\cite{khasiyev2024safety}, aucune association n'a pu être établie avec le devenir neurologique à long terme des patients traités~\cite{bernhardt2024hypertonic}. Les mécanismes d'actions sont pas complètement identifiés, et ne peuvent être résumés au drainage osmotique du liquide interstitiel cérébral dans la circulation sanguine~\cite{park2024should}. L'injection de SSH provoque également une augmentation de volume sanguin induisant un déplacement d'eau de l'intérieur vers l'extérieur de la membrane des globules rouges. Le débit sanguin cérébral est alors augmenté par la conjonction de trois effets : hémodilution, augmentation du diamètre de la lumière endothéliale et diminution du diamètre des globules rouges (). Les mécanismes d'autorégulation cérébrale sont alors mis en jeu et causent une vasoconstriction réflexe, menant finalement à une baisse du volume sanguin cérébral et donc de la PIC (). Ces effets ne sont cependant par immédiats ; il faut compter 20 à 30 minutes après l'injection de SSH avant la formation du gradient osmotique~\cite{park2024should}. Cette modification induite du volume sanguin cérébral constitue donc un contexte utile à l'étude de la compliance cérébrale des patients traités par injection de SSH. L'objectif de la ré-analyse est d'étudier les changements dans la morphologie des pulsations cardiaques sur le signal de PIC lors de l'augmentation des réserves de compliance cérébrale induite par l'injection de SSH. En d'autres termes, la diminution du volume cérébral induite par l'injection de SSH est utilisée comme référence pour identifier les aspects de la compliance cérébrales captés par la morphologie de la composante cardiaque du signal de PIC.
5 5  
6 6 \section{Matériel et méthodes}
7 7  
8 8 \subsection{Collecte des données}
9   -Comme décrit dans la première publication~\cite{dias2014post}, les patients inclus dans l'étude souffraient d'un traumatisme crânien associé à un \textit{Glasgow Coma Scale} inférieur à 8 à l'admission en unité de neuro-réanimation. Les patients étaient traités avec une élévation de la tête de 30°. Le niveau de PPC visé était dans la mesure du possible défini en cherchant à minimiser le PRx, et maintenu $>$ 60 mmHg sinon. La PIC était monitorée au moyen d'un capteur intraparenchymateux (Codman) à une fréquence d'échantillonnage de 250 Hz. En plus de la PIC elle-même, quatre indicateurs de la forme des pulsations cardiaques sont étudiés ici : l'amplitude des pulsations cardiaques (AMP), le ratio P2/P1, le \textit{pulse shape index} (PSI) et le \textit{time-to-peak} (TTP), correspondant au temps en ms entre le début et le maximum d'une pulsation cardiaque.
  9 +Les enregistrements de PIC de dix patients adultes atteints de TC, admis en unité de soins intensifs à l'hôpital de São Jão (Porto, Portugal), ont été ré-analysés. Comme décrit dans la publication originale~\cite{dias2014post}, les patients inclus dans l'étude souffraient d'un TC associé à un \textit{Glasgow Coma Scale} inférieur à 8 à l'admission en unité de neuro-réanimation. Tout au long du traitement, les patients étaient maintenus en position semi-assise avec une élévation de la tête de 30°. Le niveau de PPC visé était dans la mesure du possible défini en cherchant à minimiser le PRx, et maintenu $>$ 60 mmHg sinon. La PIC était monitorée au moyen d'un capteur intraparenchymateux (Codman) à une fréquence d'échantillonnage de 250 Hz. Un bolus de solution saline concentrée à 20\% était administré à raison de 0.5 mL/kg durant 30 min pour traiter les épisodes d'HIC (PIC $>$ 20 mmHg) réfractaires aux traitements de première intension visant le pH sanguin, la ventilation, la PA et la température systémique. Au total, les monitorages de 89 bolus répartis sur les dix patients (minimum: 1, maximum: 29, médiane: 5.5) ont pu être ré-analysés. En plus de la PIC elle-même, quatre indicateurs de la forme des pulsations cardiaques sont étudiés ici : l'amplitude des pulsations cardiaques (AMP), le ratio P2/P1, le \textit{pulse shape index} (PSI) et le \textit{time-to-peak} (TTP), correspondant au temps en ms entre le début et le maximum d'une pulsation cardiaque.
10 10  
11 11 \subsection{Modèles statistiques}
12   -La PIC ainsi que les différents descripteurs morphologiques sont moyennées par sections d'une demi-heure et calculées sur une durée de 4h30, de manière à ce que l'injection de SSH soit située au bout d'une heure de suivi. À partir du temps d'injection de SSH, les évolutions de ces quatre indicateurs, ainsi que celle de la PIC, sont modélisées par un modèle mixte quadratique. La colinéarité entre le temps et carré du temps est éliminée par une orthogonalisation de Gram-Schmidt. Les effets aléatoires sont hiérarchisés sur deux niveaux, de façon à considérer l'effet bolus et l'effet patient. La décision de conserver un effet fixe dans le modèle est prise sur la base d'un \textit{t-test} de non-nullité. Les effets aléatoires sont sélectionnés selon la procédure suivante :
  12 +La PIC ainsi que les différents descripteurs morphologiques sont moyennées par sections d'un quart d'heure et calculées sur une durée de 4h30, de manière à ce que l'injection de SSH soit située au bout d'une heure de suivi. Les évolutions de la PIC et des quatre indicateurs de compliance cérébrale sont modélisées par un modèle mixte quadratique couvrant les deux heures suivant l'injection de SSH. La variable temps est centrée avant l'élévation au carré de façon à limiter les effets de colinéarité. Les effets aléatoires sont hiérarchisés sur deux niveaux, de façon à considérer l'effet bolus et l'effet patient. La décision de conserver un effet fixe dans le modèle est prise sur la base d'un \textit{t-test} de non-nullité. Les effets aléatoires sont sélectionnés selon la procédure suivante :
13 13 \begin{enumerate}
14 14 \item Un premier modèle de référence est entraîné en incluant tous les effets aléatoires possibles.
15 15 \item Un second modèle est entraîné en retirant un effet aléatoire. Ses performances sont comparées à celles du premier modèle sur la base d'un test de ratio de vraisemblance (\textit{likelihood ratio test}). Si le second modèle n'est pas significativement (\textit{p-value} $<$ 0.05) moins prédictif que le modèle de référence, celui devient le modèle de référence.
16 16  
17 17  
18 18  
19 19  
20 20  
21 21  
22 22  
23 23  
24 24  
25 25  
26 26  
... ... @@ -25,54 +25,108 @@
25 25 \begin{figure}[h!]
26 26 \centering
27 27 \includegraphics[width=1\linewidth]{HTS/exemple.jpg}
28   - \caption{Exemple d'évolution du signal de PIC après injection de SSH. L'injection est pratiquée à \textit{t} = 0.}
  28 + \caption{Exemple d'évolution du signal de PIC après injection de SSH. Le début de l'injection est effectué à \textit{t} = 0.}
29 29 \label{fig:HTS-exemple}
30 30 \end{figure}
31 31  
  32 +L'évolution des différents descripteurs du signal de PIC est présentée figure~\ref{HTS-boxplots}. Les effets fixes des modèles retenus sont représentés sur les deux heures suivant l'injection de SSH.
  33 +
  34 +\begin{figure}[h!]
  35 + \centering
  36 + \includegraphics[width=1\linewidth]{HTS/boxplots.png}
  37 + \caption{Évolution des différents descripteurs du signal de PIC au cours du temps. Le début de l'injection est effectué à \textit{t }= 0.}
  38 + \label{fig:HTS-boxplots}
  39 +\end{figure}
  40 +
  41 +
32 42 \subsection{Modélisation mixte quadratique}
33   -Les coefficients des modèles retenus sont présentés dans le tableau~\ref{hts-tab:coefs}. Concernant les effets fixes, la PIC, l'AMP et le ratio P2/P1 décrivent une trajectoire quadratique. Les coefficients fixes des autres descripteurs de forme (TPP et PSI) ne sont pas significativement non-nuls. Les effets aléatoires au niveau de l'individu ne sont pas conservés pour la PIC et l'AMP. La variance sur la réponse à l'injection, décrite par les effets aléatoires sur le temps et le carré du temps, est principalement captée au niveau "bolus". En revanche, une dichotomie s'observe sur les variations de ligne de base, captées par les écarts types des effets aléatoires sur les intercepts. Ces écarts types sont plus importants au niveau "bolus" pour la PIC et pour l'amplitude, mais plus importants au niveau "individu" pour les trois indicateurs de morphologie (PSI, TTP, P2/P1).
34 43  
  44 +
  45 +Les coefficients des modèles retenus sont présentés dans le tableau~\ref{hts-tab:coefs}. Au niveau des effets fixes, l'ensemble des descripteurs décrivent une trajectoire quadratique. Concernant les effets aléatoires, la variabilité de la réponse à l'injection de SSH (décrite par l'écart type des coefficients liés au temps et à son carré) est beaucoup moins marquée à l'échelle de l'individu qu'à l'échelle du bolus ; les modèles du ratio et du PSI n'incluent d'ailleurs pas ces effets aléatoires au niveau "individu". En revanche, une dichotomie s'observe sur les variations de ligne de base, captées par les effets aléatoires sur les intercepts. Les écarts types associés sont plus importants au niveau "bolus" pour la PIC et pour l'amplitude, mais plus importants au niveau "individu" pour les trois indicateurs de morphologie (PSI, TTP, P2/P1). En particulier, le modèle de la PIC ne comporte pas d'intercept aléatoire au niveau de l'individu.
  46 +
35 47 \begin{table}[h!]
36 48 \centering
37 49 \resizebox{\columnwidth}{!}{%
38   - \begin{tabular}{|c|ccc|ccc|ccc|}\toprule
39   - & \multicolumn{3}{|c}{coefficients}& \multicolumn{6}{|c|}{écarts types}\\
40   - \midrule
41   - & \multicolumn{3}{|c}{effets fixes} & \multicolumn{3}{|c|}{aléatoire --- individu} & \multicolumn{3}{c|}{aléatoire --- bolus} \\
42   - \hline
43   - & intercept & temps & temps² & intercept & temps & temps² & intercept & temps & temps² \\
  50 + \begin{tabular}{|c||ccc|ccc|ccc|}\toprule
  51 + & \multicolumn{3}{c|}{effets fixes}& \multicolumn{3}{c}{aléatoire --- individu}& \multicolumn{3}{|c|}{aléatoire --- bolus}\\\midrule
  52 + & intercept& temps& temps²& intercept& temps& temps²& intercept& temps& temps²\\
44 53 \hline
45   -
46   - PIC (mmHg) & 18.45 & -48.76 & 73.72 & 2.93 & - & - & 3.34 & 71.16 & 76.31 \\
47   - Amplitude (mmHg) & 8.07 & -18.12 & 25.42 & 2.21 & - & - & 2.58 & 31.02 & 28.03 \\
48   - PSI & 2.94 & - & - & 0.80 & 2.26 & 1.34 & 0.38 & 4.32 & 4.22 \\
49   - time-to-peak (sec) & 0.225 & - & - & 0.072 & 0.71 & 0.35 & 0.051 & 0.50 & 0.61 \\
50   - P2/P1 & 1.47 & -0.97 & 2.05 & 0.50 & 1.60 & 0.64 & 0.24 & 3.9 & 2.28 \\
51   - \bottomrule
52   - \end{tabular}
  54 + PIC (mmHg)& 17.28& -0.80& 0.42& -& 0.26& 0.22& 7.48& 1.38& 0.38\\
  55 + Amplitude (mmHg)& 7.5& -0.28& 0.15& 2.04& 0.14& 0.08& 4.16& 0.59& 0.16\\
  56 + PSI& 2.64& -0.0032& 0.0012& 0.75& -& -& 0.56& 0.058& 0.031\\
  57 + time-to-peak (sec)& 0.22& -0.0010& 0.0018& 0.090& 0.0066& 0.00055& 0.064& 0.0088&0.0036\\
  58 + P2/P1& 1.38& -0.012& 0.016& 0.49& -& -& 0.32& 0.058&0.021\\ \bottomrule
  59 + \end{tabular}
53 60 }
54 61 \caption{Modèles mixtes quadratiques retenus. Les effets fixes sont décrits par les coefficients correspondants, les effets aléatoires par les écarts types associés.}
55 62 \label{hts-tab:coefs}
56 63 \end{table}
57 64  
58   -\subsection{Réponse à l'injection de HTS selon la PIC et le ratio P2/P1 initiaux}
59   -Les modifications du signal de PIC induites par l'injection de HTS sont mesurées en calculant la différence des indicateurs entre la demi-heure précédant l'injection et le niveau le plus bas observé parmi les sections moyennées d'une demi-heure suivant l'injection. En particulier, la figure~\ref{fig:HTS-baseline} présente les baisses de PIC et de ratio P2/P1 induites en fonction des niveaux de PIC et de ratio P2/P1 observés au moment de l'injection.
  65 +\subsection{Réponses à l'injection de de SSH}
  66 +Les trajectoires quadratiques des différents indicateurs modélisées pour chaque bolus sont utilisées pour quantifier les réponses à l'injection de SSH. Selon les cas, il n'est pas systématiquement possible d'identifier un minimum local dans la trajectoire des prédicteurs. Ces proportions sont reportées dans la table~\ref{hts-tab:kept}. Probablement du fait de sa nature discrète, le PSI propose le moins de trajectoires exploitables avec seulement 64 minima locaux identifiés suite aux 89 injections.
60 67  
  68 +\begin{table}[h!]
  69 + \centering
  70 + \begin{tabular}{|c|c|c|}
  71 + \hline
  72 + Descripteur& Minima identifiés& Pourcentage \\
  73 + \hline
  74 + PIC& 83& 93.25 \%\\
  75 + Amplitude& 83& 93.25 \%\\
  76 + PSI& 64& 71.89 \%\\
  77 + time-to-peak& 69& 77.52\%\\
  78 + P2/P1& 75& 84.27\%\\
  79 + \hline
  80 + \end{tabular}
  81 + \caption{Proportions de minima locaux identifiés dans les trajectoires des différents indicateurs.}
  82 + \label{hts-tab:kept}
  83 +\end{table}
  84 +
  85 +Pour chaque bolus, la différence entre le temps d'arrivée du minimum local de la PIC et des différents indicateurs est modélisée par un modèle d'intercept aléatoire prenant en compte l'effet individu. Les effets fixes sont reportés dans la table~\ref{hts-tab:delay}. Aucune différence significative ne peut être mise en évidence entre le temps d'arrivée du minimum de PIC et le temps d'arrivée du minimum des différents indicateurs, suggérant une cinétique commune.
  86 +
  87 +\begin{table}[h!]
  88 + \centering
  89 + \begin{tabular}{|c|c|c|}
  90 + \hline
  91 + Différence& Effet fixe& \textit{p}-value\\
  92 + \hline
  93 + Amplitude - PIC& -1.37& 0.40\\
  94 + PSI - PIC& 3.08& 0.25\\
  95 + TTP - PIC& 3.8& 0.67\\
  96 + P2/P1 - PIC& 0.5& 0.81\\
  97 +\hline
  98 + \end{tabular}
  99 + \caption{Différence entre le temps d'arrivée du minimum de PIC et des différents indicateurs de compliance cérébrale. PSI --- \textit{Pulse shape index}, TTP --- \textit{Time-to-peak}}
  100 + \label{hts-tab:delay}
  101 +\end{table}
  102 +
  103 +La baisse de la PIC ainsi que des différents indicateurs peut également être étudiée en calculant la différence entre l'état initial et le minimum observé pour chacun des indicateurs. La figure~\ref{fig:HTS-exemple} présente l'exemple des états initiaux et des baisses observées pour la PIC et le ratio P2/P1.
  104 +
61 105 \begin{figure}[h!]
62 106 \centering
63   - \includegraphics[width=1\linewidth]{HTS/full.png}
64   - \caption{Baisses du niveau de PIC et de ratio P2/P1 observés en fonction du niveau initial de PIC et de ratio P2/P1.}
65   - \label{fig:HTS-baseline}
  107 + \includegraphics[width=1\linewidth]{HTS/ir.png}
  108 + \caption{Réponse de la PIC moyenne et du ratio P2/P1 à l'injection de SSH, en fonction des niveaux de PIC et des ratios P2/P1 initiaux.}
  109 + \label{fig:HTS-exemple}
66 110 \end{figure}
67 111  
68   -De même que pour la PIC moyenne, le ratio P2/P1 moyen est fortement corrélé à la baisse de ratio P2/P1 observée. Si les PIC initiales élevées tendent à être associés à une plus forte de baisse de ratio P2/P1(r=0.24), la morphologie initiale des pulsations cardiaques n'est pas du tout prédictive de la réponse de la PIC moyenne à l'injection de SSH. La carte des corrélation entre l'ensemble des descripteurs utilisés est présentée figure~\ref{fig:HTS-heatmap}.
  112 +De forts effets individuels sont visibles sur les exemples de la PIC et du ratio P2/P1. La matrice complète des corrélations entre les différents descripteurs est calculée en corrigeant l'effet "patient" des coefficients calculés. Pour ce faire, la méthodologie des corrélations de mesures répétées (\textit{repeated measures correlation}, rmcorr) est utilisée. Celle-ci se base sur les coefficients d'un modèle d'ANCOVA~\cite{bakdash2017repeated}. La matrice de corrélation complète est présentée figure~\ref{fig:HTS-corr}. Les baisses de PIC, d'amplitude et de ratio P2/P1 sont sensiblement proportionnelles à leurs niveaux initiaux respectifs, affichant des corrélations de 0.83, 0.9 et 0.79. L'amplitude et la PIC suivent des trajectoires très similaires, avec des corrélations très élevées ($>0.8$) entre leurs niveaux initiaux et leurs baisses respectives. Une séparation s'observe entre les descripteurs purement morphologiques (PSI, P2/P1, TTP) et les valeurs en mmHg (PIC, amplitude) au niveau des lignes de base. Il convient de mentionner que la PIC initiale est un relativement bon prédicteur des changements de morphologie observés sur le PSI, le ratio P2/P1 et le TTP (les corrélations respectives sont de 0.54, 0.37 et 0.19), tandis que la morphologie initiale du signal de PIC est un indicateur beaucoup moins fiable de la baisse de la PIC (les corrélations respectives sont de 0.14, 0.21 et - 0.04). Le même raisonnement peut être tenu en considérant l'amplitude au lieu de la PIC moyenne.
69 113  
70 114 \begin{figure}[h!]
71 115 \centering
72   - \includegraphics[width=1\linewidth]{HTS/heatmap.png}
73   - \caption{Carte des corrélations entre les différents descripteurs du signal de PIC. PIC --- pression intracrânienne, AMP --- amplitude des pulsations cardiaques, PSI --- \textit{pulse shape index}}
74   - \label{fig:HTS-heatmap}
  116 + \includegraphics[width=1\linewidth]{HTS/correlation.png}
  117 + \caption{Matrice de corrélation entre les réponses des différents indicateurs à l'injection de HTS, en fonction des niveaux initiaux observés. Les corrélations sont calculées en corrigeant les effets individuels.}
  118 + \label{fig:HTS-corr}
75 119 \end{figure}
76 120  
77   -Les descripteurs du signal de PIC se répartissent en deux groupes, avec d'un côté les indices purement morphologiques (ratio P2/P1, PSI, TTP) et de l'autre la PIC moyenne et l'amplitude. Cette séparation est très marquée dans les corrélations deux à deux entre lignes de base, mais moins dans les différences induites par l'injection de SSH. À l'exception du PSI, il existe une bonne corrélation positive entre les niveaux initiaux des indicateurs et leur baisse induite par l'injection de SSH.
  121 +\section{Discussion}
  122 +L'étude initiale avait pu mettre en évidence différents effets de l'injection de HTS : baisse de la PIC (moyenne = 6.2 mmHg), augmentation de la PPC (moyenne = 3.1 mmHg), augmentation du débit sanguin cérébral (moyenne = 7.8 mL/min/100g). De plus, des effets bénéfiques sur l'autorégulation sur des indices de corrélation tels que le PRx avaient été observés. Concernant la compliance cérébrale, des modifications de ratio P2/P1 et d'amplitude avaient été mentionnés, sans pour autant faire l'object d'études quantitatives. Pour compléter l'étude morphologique du signal de PIC, deux indicateurs ont été ajoutés : le PSI et le TTP.
  123 +\subsection{Signification clinique de la morphologie du signal de PIC}
  124 +\par L'évolution du signal de PIC ainsi que des quatre indicateurs suivent une trajectoire quadratique au cours des deux heures suivant le début de l'injection de SSH. En plus de la baisse de la PIC, les quatre indicateurs de compliance cérébrale tendent également vers des valeurs plus physiologiques, avec des minima atteints entre une heure et une heure et quart. Cette première observation peut s'expliquer par la libération de réserves de compliance provoquée par l'injection de SSH, menant à une diminution du volume sanguin cérébral. Pour les cinq séries temporelles, la variance des trajectoires observées est principalement captée par les effets aléatoires au niveau du bolus, suggérant une forte hétérogénéité intra-patient de la réponse à l'injection de SSH. En revanche, en regardant les effets aléatoires sur les intercepts, une séparation peut être effectuée entre la PIC et l'amplitude d'un côté, et le PSI, le TTP et le P2/P1 et de l'autre. En effet, dans le premier groupe, la variance est surtout captée à l'échelle du bolus (le modèle de la PIC n'intégrant d'ailleurs pas d'intercept aléatoire au niveau ''patient''). En revanche, dans le second groupe, la variance des intercepts aléatoires est davantage captée à l'échelle de l'individu. Par exemple dans le cas du ratio P2/P1, l'écart type des intercepts aléatoires est de 0.49 au niveau individuel et de 0.32 au niveau bolus. Cela suggère qu'indépendemment du temps, le signal de PIC tend vers certaines morphologies propres à chaque patient. Ces résultats peuvent être expliqués en considérant que la morphologie du signal de PIC, quantifiée par le ratio P2/P1, est largement influencée par certaines propriétés mécaniques de l'arbre vasculaire cérébral, et en particulier l'élastance des artères cérébrales~\cite{domogo2023mechanistic}. Au contraire, l'amplitude est principalement liée aux réserves de volume disponibles~\cite{kasprowicz2025impact}. Ainsi, les indicateurs purement morphologiques (PSI, P2/P1, TTP) sont plus stables dans le temps pour un patient donné.
  125 +\par Cette interprétation peut être confirmée en s'appuyant sur la relation existant entre les niveaux initiaux des différents indicateurs et leurs baisses causées par le bolus de SSH. En particulier, l'injection provoque une baisse de PIC proportionnelle au niveau initial observé. En revanche, les effets individuels sont davantage marqués lorsque la modification de la morphologie est tracée en fonction de la PIC initiale (voir figure ~\ref{fig:HTS-exemple}). Ainsi, la morphologie du signal de PIC doit être interprétée en regard de ses deux déterminants : l'effet volume, expliquant que le ratio P2/P1 peut être utilisé comme marqueur d'HTIC~\cite{ballestero2023can}, et l'effet de propriétés mécanique des artères cérébrales. Ainsi, les niveaux initiaux de PIC (ou d'amplitude) sont des bons prédicteurs de l'ampleur des changements observés sur le PSI (corrélation = 0.54) ou le ratio P2/P1 (corrélation = 0.37) après injection de SSH (voir figure~\ref{fig:HTS-corr}), dans la mesure où le soulagement d'une forte HTIC libère des espaces de compliance et impacte donc la morphologie de la PIC en jouant sur son déterminant volumique. En revanche, les niveaux initiaux du PSI et du ratio P2/P1 ne sont que faiblement prédictifs de la baisse de la PIC observés, avec des corrélations respectives de 0.14 et 0.21. En effet, des valeurs élevées peuvent autant être dues à des réserves volumiques épuisées qu'à une forte élastance des artères cérébrales.
  126 +
  127 +\subsection{Limites}
  128 +La principale limite de cette étude réside dans le faible nombre de patients (\textit{n}=10) et dans la forte hétérogénéité du nombre de bolus de SSH administrés. Les hypothèses posées dans la discussion sont limitées d'une part par la compréhension partielle des mécanismes d'action de l'injection de HTS, et d'une autre par l'impossibilité de suivre les changements volumiques au cours des deux heures d'analyse. Les résultats présentés ici doivent être validés sur une plus grande cohorte en séparant les déterminants volumiques et mécaniques de la morphologie du signal de PIC.
  129 +
  130 +\subsection{Conclusion}
  131 +La diminution du volume cérébral induite par l'injection de SSH permet d'étudier les différents aspects de la compliance cérébrale captés par la morphologie du signal de PIC. Cette dernière est un faible prédicteur de la baisse de PIC causée par l'osmothérapie. Le PSI et le ratio P2/P1 intègrent une première composante liée aux propriétés mécaniques des parois vasculaires cérébrales, et une seconde liée au volume de réserve. En revanche, l'amplitude, dont la trajectoire suit largement celle de la PIC, intègre principalement la composante liée au volume de réserve.
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61 60 \chapter*{Conclusion et perspectives}
62 61 \addcontentsline{toc}{chapter}{Conclusions et perspectives}
63 62  
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